Search Results - "Schrumpf, Holger"
-
1
The pruritus- and TH2-associated cytokine IL-31 promotes growth of sensory nerves
Published in Journal of allergy and clinical immunology (01-08-2016)“…Pruritus is a cardinal symptom of atopic dermatitis, and an increased cutaneous sensory network is thought to contribute to pruritus. Although the immune…”
Get full text
Journal Article -
2
Epidermal EGFR controls cutaneous host defense and prevents inflammation
Published in Science translational medicine (21-08-2013)“…The epidermal growth factor receptor (EGFR) plays an important role in tissue homeostasis and tumor progression. However, cancer patients treated with EGFR…”
Get more information
Journal Article -
3
EGFR/Ras-induced CCL20 production modulates the tumour microenvironment
Published in British journal of cancer (15-09-2020)“…Background The activation of the EGFR/Ras-signalling pathway in tumour cells induces a distinct chemokine repertoire, which in turn modulates the tumour…”
Get full text
Journal Article -
4
Standardized in vitro analysis of the degradability of hyaluronic acid fillers by hyaluronidase
Published in European journal of medical research (20-08-2018)“…Hyaluronidase is a hyaluronic acid (HA) metabolizing enzyme, which is approved as an adjuvant for infiltration anesthesia. The "off-label" use of hyaluronidase…”
Get full text
Journal Article -
5
Correction to: EGFR/Ras-induced CCL20 production modulates the tumour microenvironment
Published in British journal of cancer (01-10-2021)Get full text
Journal Article -
6
Transcanalicular laser dacryocystorhinostomy for acquired nasolacrimal duct obstruction: an audit of 104 patients
Published in European journal of medical research (16-11-2018)“…External dacryocystorhinostomy (DCR) is considered as the gold standard in the treatment of acquired nasolacrimal duct obstruction. However, many advances have…”
Get full text
Journal Article -
7
Systematic identification and characterization of novel human skin-associated genes encoding membrane and secreted proteins
Published in PloS one (20-06-2013)“…Through bioinformatics analyses of a human gene expression database representing 105 different tissues and cell types, we identified 687 skin-associated genes…”
Get full text
Journal Article -
8
Ingenol mebutate induces a tumor cell-directed inflammatory response and antimicrobial peptides thereby promoting rapid tumor destruction and wound healing
Published in European journal of medical research (28-09-2018)“…Ingenol mebutat (IM)-gel is effective for the topical treatment of epithelial tumors, including actinic keratoses (AKs) or anogenital warts (AGW). AK patients…”
Get full text
Journal Article -
9
Influence of a Calcium Phosphate Coating (BONIT®) on the Proliferation and Differentiation Potential of Human Mesenchymal Stroma Cells in the Early Phase of Bone Healing
Published in Journal of functional biomaterials (06-10-2022)“…When implanting osteosynthetic materials or orthopedic implants, the surface condition plays a decisive role for mid- to long-term osseointegration. BONIT®, an…”
Get full text
Journal Article -
10
The role of oxidative and nitrosative stress in the pathology of osteoarthritis: Novel candidate biomarkers for quantification of degenerative changes in the knee joint
Published in Orthopedic Reviews (14-06-2018)“…Osteoarthritis (OA) is the most frequently diagnosed joint disorder worldwide with increasing prevalence and crucial impact on the quality of life of affected…”
Get full text
Journal Article -
11
Treatment of melasma in Caucasian patients using a novel 694-nm Q-switched ruby fractional laser
Published in European journal of medical research (14-11-2013)“…Melasma is a common hypermelanosis of the face. The use of a classical Q-switched ruby laser (QSRL) to treat melasma is discussed controversially and is…”
Get full text
Journal Article -
12
Management of EGFR-inhibitor associated rash: a retrospective study in 49 patients
Published in European journal of medical research (23-02-2012)“…In recent years inhibitors directed against the epidermal growth factor receptor (EGFR) have evolved as effective targeting cancer drugs. Characteristic…”
Get full text
Journal Article -
13
-
14
Hyaluronidase: from clinical applications to molecular and cellular mechanisms
Published in European journal of medical research (13-02-2016)“…Over the past 60 years, hyaluronidase has been successfully utilized in ophthalmic surgery and is now being implemented in dermatosurgery as well as in other…”
Get full text
Journal Article -
15
The top skin-associated genes: a comparative analysis of human and mouse skin transcriptomes
Published in Biological chemistry (01-06-2014)“…The mouse represents a key model system for the study of the physiology and biochemistry of skin. Comparison of skin between mouse and human is critical for…”
Get more information
Journal Article -
16
Clinical Applications of Hyaluronidase
Published in Advances in experimental medicine and biology (01-01-2019)“…Hyaluronidases are enzymes that degrade hyaluronic acid, which constitutes an essential part of the extracellular matrix. Initially discovered in bacteria,…”
Get more information
Journal Article -
17
Time- and Dose-Dependent Effects of Hyaluronidase on the Degradation of Different Hyaluronan-Based Fillers In Vitro
Published in Plastic and reconstructive surgery (1963) (01-03-2023)“…Hyaluronidase (HYAL) is regarded as the standard for the management of complications associated with hyaluronan (HA)-based fillers. Therefore, the…”
Get full text
Journal Article -
18
METEORIN-LIKE is a cytokine associated with barrier tissues and alternatively activated macrophages
Published in Clinical immunology (Orlando, Fla.) (01-02-2015)“…Abstract Cytokines are involved in many functions of the immune system including initiating, amplifying and resolving immune responses. Through bioinformatics…”
Get full text
Journal Article -
19
Tensiomyography parameters and serum biomarkers after eccentric exercise of the elbow flexors
Published in European journal of applied physiology (01-02-2019)“…Purpose The tensiomyography (TMG) technique is increasingly used to determine muscle contractile properties in exercise and injury management. The present…”
Get full text
Journal Article -
20
Dose- and time-dependent effects of hyaluronidase on structural cells and the extracellular matrix of the skin
Published in European journal of medical research (23-11-2020)“…Abstract Introduction Hyaluronic acid (hyaluronan; HA) is an essential component of the extracellular matrix (ECM) of the skin. The HA-degrading enzyme…”
Get full text
Journal Article