Search Results - "Schroeter, D."

Olfactory deposition of inhaled nanoparticles in humans by Garcia, Guilherme J. M., Schroeter, Jeffry D., Kimbell, Julia S.

“…Context: Inhaled nanoparticles can migrate to the brain via the olfactory bulb, as demonstrated in experiments in several animal species. This route of…”
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Effects of surface smoothness on inertial particle deposition in human nasal models by Schroeter, Jeffry D., Garcia, Guilherme J.M., Kimbell, Julia S.

“…Computational fluid dynamics (CFD) predictions of inertial particle deposition have not compared well with data from nasal replicas due to effects of surface…”
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Physiologically Based Pharmacokinetic Modeling of Fetal and Neonatal Manganese Exposure in Humans: Describing Manganese Homeostasis during Development by Yoon, Miyoung, Schroeter, Jeffry D., Nong, Andy, Taylor, Michael D., Dorman, David C., Andersen, Melvin E., Clewell, Harvey J.

“…Concerns for potential vulnerability to manganese (Mn) neurotoxicity during fetal and neonatal development have been raised due to increased needs for Mn for…”
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Hall Effect and Resistivity in Epitaxial MnSi Thin Films Under Ambient and High Pressure by Menzel, D., Schroeter, D., Steinki, N., Sullow, S., Fernandez Scarioni, Alexander, Schumacher, H. W., Okuyama, H., Hidaka, H.

“…Thin film MnSi has been epitaxially grown on Si(111) substrate and investigated in terms of magnetoresistance and Hall measurements under applied hydrostatic…”
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Electronic transport properties of nanostructured MnSi-films by Schroeter, D., Steinki, N., Scarioni, A. Fernández, Schumacher, H.W., Süllow, S., Menzel, D.

“…MnSi, which crystallizes in the cubic B20 structure, shows intriguing magnetic properties involving the existence of skyrmions in the magnetic phase diagram…”
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Assessing standards of evidence in evidence-based program registers for behavioral health treatments by Magura, Stephen, Burkhardt, J, Schroeter, D, Means, S, Vladimirovna, Y, Coryn, C

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Computational fluid dynamics simulations of inhaled nano- and microparticle deposition in the rhesus monkey nasal passages by Schroeter, Jeffry D., Asgharian, Bahman, Price, Owen T., McClellan, Gene E.

“…Abstract Anatomically accurate computational fluid dynamics (CFD) models of the nasal passages of an infant (6 months old, 1.3 kg) and adult (7 years old, 11.9…”
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Electronic transport in high magnetic fields of thin film MnSi by Steinki, N, Schroeter, D, Wächter, N, Menzel, D, Schumacher, H W, Sheikin, I, Süllow, S

“…We present a study of the magnetoresistivity of thin film MnSi in high magnetic fields. We establish that the magnetoresistivity can be understood in terms of…”
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Application of Physiological Computational Fluid Dynamics Models to Predict Interspecies Nasal Dosimetry of Inhaled Acrolein by Schroeter, Jeffry D., Kimbell, Julia S., Gross, Elizabeth A., Willson, Gabrielle A., Dorman, David C., Tan, Yu-Mei, Clewell, Harvey J.

“…Acrolein is a highly soluble and reactive aldehyde and is a potent upper-respiratory-tract irritant. Acrolein-induced nasal lesions in rodents include…”
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Use of a Pharmacokinetic-Driven Computational Fluid Dynamics Model to Predict Nasal Extraction of Hydrogen Sulfide in Rats and Humans by Schroeter, Jeffry D., Kimbell, Julia S., Andersen, Melvin E., Dorman, David C.

“…Hydrogen sulfide (H2S) is a naturally occurring and industrially generated gas. Human exposure to H2S results in dose-related neurological, respiratory, and…”
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Fundamental effects of particle morphology on lung delivery: Predictions of stokes' law and the particular relevance to dry powder inhaler formulation and development by CROWDER, Timothy M, ROSATI, Jacky A, SCHROETER, Jeffry D, HICKEY, Anthony J, MARTONEN, Ted B

“…Key factors that contribute to the aerodynamic properties of aerosol particles are found in Stokes' law. These factors may be monitored or controlled to…”
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Tissue distribution of inhaled micro- and nano-sized cerium oxide particles in rats: results from a 28-day exposure study by Geraets, Liesbeth, Oomen, Agnes G, Schroeter, Jeffry D, Coleman, Victoria A, Cassee, Flemming R

“…In order to obtain more insight into the tissue distribution, accumulation, and elimination of cerium oxide nanoparticles after inhalation exposure, blood and…”
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3D in silico modeling of the human respiratory system for inhaled drug delivery and imaging analysis by Martonen, T B, Schroeter, J D, Fleming, J S

“…The efficacies of inhaled pharmacologic drugs could be improved if drugs could be targeted to appropriate sites within the human respiratory system. The…”
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Update on a Pharmacokinetic-Centric Alternative Tier II Program for MMT-Part II: Physiologically Based Pharmacokinetic Modeling and Manganese Risk Assessment by Taylor, Michael D., Clewell, Harvey J., Andersen, Melvin E., Schroeter, Jeffry D., Yoon, Miyoung, Keene, Athena M., Dorman, David C.

“…Recently, a variety of physiologically based pharmacokinetic (PBPK) models have been developed for the essential element manganese. This paper reviews the…”
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Risk assessment dosimetry model for inhaled particulate matter: I. Human subjects by Martonen, Ted B, Schroeter, Jeffry D

“…Pollutant particulate matter (PM) is a serious global problem, presenting a threat to the health and well being of human subjects. Inhalation exposures tests…”
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Experimental measurements and computational predictions of regional particle deposition in a sectional nasal model by Schroeter, Jeffry D, Tewksbury, Earl W, Wong, Brian A, Kimbell, Julia S

“…Knowledge of the regional deposition of inhaled particles in the nose is important for drug delivery and assessment of the toxicity of inhaled materials. In…”
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Factors affecting the deposition of inhaled porous drug particles by Musante, Cynthia J, Schroeter, Jeffry D, Rosati, Jacky A, Crowder, Timothy M, Hickey, Anthony J, Martonen, Ted B

“…Recent findings indicate that the inhalation of large manufactured porous particles may be particularly effective for drug delivery. In this study, a…”
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Incorporation of Tissue Reaction Kinetics in a Computational Fluid Dynamics Model for Nasal Extraction of Inhaled Hydrogen Sulfide in Rats by Schroeter, Jeffry D., Kimbell, Julia S., Bonner, Anna M., Roberts, Kay C., Andersen, Melvin E., Dorman, David C.

“…Rodents exposed to hydrogen sulfide (H2S) develop olfactory neuronal loss. This lesion has been used by the risk assessment community to develop occupational…”
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Effects of endogenous formaldehyde in nasal tissues on inhaled formaldehyde dosimetry predictions in the rat, monkey, and human nasal passages by Schroeter, Jeffry D, Campbell, Jerry, Kimbell, Julia S, Conolly, Rory B, Clewell, Harvey J, Andersen, Melvin E

“…Formaldehyde is a nasal carcinogen in rodents at high doses and is an endogenous compound that is present in all living cells. Due to its high solubility and…”
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Self-electroporation as a Model for Fusion Pore Formation by Luitel, P., Schroeter, D. F., Powell, J. W.

“…The creation of a small opening called the fusion pore is a necessary prerequisite for neurotransmitter release from synaptic vesicles. It is known that high…”
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