Search Results - "Schroeder, Lindsay"

MicroRNA-Mediated Downregulation of the Potassium Channel Kv4.2 Contributes to Seizure Onset by Gross, Christina, Yao, Xiaodi, Engel, Tobias, Tiwari, Durgesh, Xing, Lei, Rowley, Shane, Danielson, Scott W., Thomas, Kristen T., Jimenez-Mateos, Eva M., Schroeder, Lindsay M., Pun, Raymund Y.K., Danzer, Steve C., Henshall, David C., Bassell, Gary J.

“…Seizures are bursts of excessive synchronized neuronal activity, suggesting that mechanisms controlling brain excitability are compromised. The voltage-gated…”
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MicroRNA inhibition upregulates hippocampal A-type potassium current and reduces seizure frequency in a mouse model of epilepsy by Tiwari, Durgesh, Brager, Darrin H., Rymer, Jeffrey K., Bunk, Alexander T., White, Angela R., Elsayed, Nada A., Krzeski, Joseph C., Snider, Andrew, Schroeder Carter, Lindsay M., Danzer, Steve C., Gross, Christina

“…Epilepsy is often associated with altered expression or function of ion channels. One example of such a channelopathy is the reduction of A-type potassium…”
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Mechanisms for Alternaria alternata Function in the Skin During Induction of Peanut Allergy in Neonatal Mice With Skin Barrier Mutations by Buelow, Lauren M, Hoji, Akihiko, Tat, Kiet, Schroeder-Carter, Lindsay M, Carroll, Daniela J, Cook-Mills, Joan M

“…Neonatal mice with heterozygous mutations in genes encoding the skin barrier proteins filaggrin and mattrin (flaky tail mice [FT ]) exhibit oral peanut-induced…”
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Increased expression of the PI3K catalytic subunit p110δ underlies elevated S6 phosphorylation and protein synthesis in an individual with autism from a multiplex family by Poopal, Ashwini C, Schroeder, Lindsay M, Horn, Paul S, Bassell, Gary J, Gross, Christina

“…Dysfunctions in the PI3K/mTOR pathway have gained a lot of attention in autism research. This was initially based on the discovery of several monogenic autism…”
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The potassium channel Kv4.2 regulates dendritic spine morphology, electroencephalographic characteristics and seizure susceptibility in mice by Tiwari, Durgesh, Schaefer, Tori L., Schroeder-Carter, Lindsay M., Krzeski, Joseph C., Bunk, Alexander T., Parkins, Emma V., Snider, Andrew, Danzer, Reese, Williams, Michael T., Vorhees, Charles V., Danzer, Steve C., Gross, Christina

“…The voltage-gated potassium channel Kv4.2 is a critical regulator of dendritic excitability in the hippocampus and is crucial for dendritic signal integration…”
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Isoform-selective phosphoinositide 3-kinase inhibition ameliorates a broad range of fragile X syndrome-associated deficits in a mouse model by Gross, Christina, Banerjee, Anwesha, Tiwari, Durgesh, Longo, Francesco, White, Angela R, Allen, A G, Schroeder-Carter, Lindsay M, Krzeski, Joseph C, Elsayed, Nada A, Puckett, Rosemary, Klann, Eric, Rivero, Ralph A, Gourley, Shannon L, Bassell, Gary J

“…Defects in the phosphoinositide 3-kinase (PI3K) pathway are shared characteristics in several brain disorders, including the inherited intellectual disability…”
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Correction to: Isoform-selective phosphoinositide 3-kinase inhibition ameliorates a broad range of fragile X syndrome-associated deficits in a mouse model by Gross, Christina, Banerjee, Anwesha, Tiwari, Durgesh, Longo, Francesco, White, Angela R, Allen, A G, Schroeder-Carter, Lindsay M, Krzeski, Joseph C, Elsayed, Nada A, Puckett, Rosemary, Klann, Eric, Rivero, Ralph A, Gourley, Shannon L, Bassell, Gary J

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β-Glucosylceramide From Allergic Mothers Enhances Offspring Responsiveness to Allergen by Walker, Matthew T, Ferrie, Ryan P, Hoji, Aki, Schroeder-Carter, Lindsay M, Cohen, Jacob D, Schnaar, Ronald L, Cook-Mills, Joan M

“…In animals and humans, offspring of allergic mothers have increased responsiveness to allergen and the allergen-specificity of the offspring can be different…”
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A Prospective Intervention to Increase Goals of Care Conversations with Hospitalized Patients Suffering Severe Stroke (Sci204) by Comer, Amber R., Sinha, Shilpee, Tormoehlen, Laura, Fettig, Lyle, Bartlett, Stephanie L., D'Cruz, Lynn E., Kassab, Veronica R., Rivera-Cordova, Xochitl G., Anderson, Leigh, Schroeder, Lindsay, Slaven, James, Torke, Alexia

“…1. Through analyzing the process and results of an intervention to increase documented goals-of-care conversations, participants will self-report the ability…”
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Abstract 12136: Bag-mask Ventilation Without Lung Inflation is Common During Out-of-Hospital 30: 2 Cardiopulmonary Resuscitation by Fredericks, Andrew, Lu, Yuanzheng, Schroeder, Lindsay, Cooper, Thomas, Floyd, Lawson, Chang, Mary, Idris, Ahamed H

“…IntroductionAmerican Heart Association guidelines for cardiopulmonary resuscitation (CPR) recommend recurring cycles of 30 chest compressions interrupted by a…”
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Immune cells encounter with α-synuclein fuels neurodegeneration in Parkinson’s disease by Pandey, Manoj K, Gross, Christina, Caballero, Madison, McKay, Mary A, Tiwari, Durgesh, Schroeder, Lindsay M, Gurtler, Michael A, Burrow, Thomas A

“…GBA1 mutations and increases of neuronal α-synulcein protein (α-syn) are the hallmark of Parkinson’s disease (PD). However, the mechanism, by which Gba1…”
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Immune cells attack and neurodegeneration in Gaucher disease by Pandey, Manoj K., Caballero, Madison, Tinch, Stuart L., Schroeder, Lindsay M., Gross, Christina, Vorhees, Charles, Burrow, Thomas A., Grabowski, Gregory A.

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Reliability Of The Bruininks-Oseretsky Test Of Motor Proficiency In Children And Adolescents With Prader-Willi Syndrome by White, Elizabeth, Schroeder, Lindsay, Wright, Pamela, Rubin, Daniela, Rose, Debra J, Wiersma, Lenny

“…Individuals with Prader-Willi Syndrome (PWS) present with overall motor deficiency, but the specific areas have yet to be identified in youth. To determine…”
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Increased expression of the PI3K catalytic subunit p110Delta underlies elevated S6 phosphorylation and protein synthesis in an individual with autism from a multiplex family by Poopal, Ashwini C, Schroeder, Lindsay M, Horn, Paul S, Bassell, Gary J, Gross, Christina

“…The PI3K/mTOR pathway regulates a variety of functions throughout the body, including fundamental processes such as cell growth, differentiation and survival…”
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Functions of an Environmental Allergen in Induction of Food Allergy by Buelow, Lauren M, Tat, Kiet, Schroeder-Carter, Lindsay, Carroll, Daniela, Hoji, Aki, Cook-Mills, Joan M

“…Food allergy can be induced in neonatal mice with heterozygous skin barrier mutations and skin co-exposure to detergent, food allergen and a ubiquitous…”
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Maternal Alpha-tocopherol Inhibits Development of Food Allergy Early in Life by Cook-Mills, Joan M, Schroeder-Carter, Lindsay M, Ramos-Solís, Nicole

“…Food allergy can be life-threatening and has had a marked recent increase in prevalence. Interventions are critical to limit the development of food allergy…”
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