Search Results - "Schroder, Heinz C"

Inorganic Polyphosphates As Storage for and Generator of Metabolic Energy in the Extracellular Matrix by Müller, Werner E.G, Schröder, Heinz C, Wang, Xiaohong

“…Inorganic polyphosphates (polyP) consist of linear chains of orthophosphate residues, linked by high-energy phosphoanhydride bonds. They are evolutionarily old…”
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Polyphosphate as a donor of high-energy phosphate for the synthesis of ADP and ATP by Müller, Werner E G, Wang, Shunfeng, Neufurth, Meik, Kokkinopoulou, Maria, Feng, Qingling, Schröder, Heinz C, Wang, Xiaohong

“…Here, we studied the potential role of inorganic polyphosphate (polyP) as an energy source for ADP and ATP formation in the extracellular space. In SaOS-2…”
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Disulfide- and Multisulfide-Containing Metabolites from Marine Organisms by Jiang, Cheng-Shi, Müller, Werner E. G, Schröder, Heinz C, Guo, Yue-Wei

“…An examination of marine organisms with disulfide- and multisulfide-containing metabolites is presented. Polysulfides from various marine organisms exhibit…”
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Engineering a morphogenetically active hydrogel for bioprinting of bioartificial tissue derived from human osteoblast-like SaOS-2 cells by Neufurth, Meik, Wang, Xiaohong, Schröder, Heinz C, Feng, Qingling, Diehl-Seifert, Bärbel, Ziebart, Thomas, Steffen, Renate, Wang, Shunfeng, Müller, Werner E.G

“…Abstract Sodium alginate hydrogel, stabilized with gelatin, is a suitable, biologically inert matrix that can be used for encapsulating and 3D bioprinting of…”
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Bioactive and biodegradable silica biomaterial for bone regeneration by Wang, Shunfeng, Wang, Xiaohong, Draenert, Florian G, Albert, Olga, Schröder, Heinz C, Mailänder, Volker, Mitov, Gergo, Müller, Werner E.G

“…Abstract Biosilica, a biocompatible, natural inorganic polymer that is formed by an enzymatic, silicatein-mediated reaction in siliceous sponges to build up…”
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Enzyme-based biosilica and biocalcite: biomaterials for the future in regenerative medicine by Wang, Xiaohong, Schröder, Heinz C, Müller, Werner E.G

“…Highlights • Results from biomineralization studies caused a paradigm shift – not only organic but also inorganic polymers are synthesized enzymatically. •…”
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Inorganic polyphosphate induces accelerated tube formation of HUVEC endothelial cells by Müller, Werner E. G., Ackermann, Maximilian, Wang, Shunfeng, Neufurth, Meik, Muñoz-Espí, Rafael, Feng, Qingling, Schröder, Heinz C., Wang, Xiaohong

“…In this study, the effect of inorganic polyphosphate (polyP) on the initial phase of angiogenesis and vascularization was investigated, applying the HUVEC cell…”
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Polyphosphate: A Morphogenetically Active Implant Material Serving as Metabolic Fuel for Bone Regeneration by Müller, Werner E. G., Tolba, Emad, Schröder, Heinz C., Wang, Xiaohong

“…The initial mineralization centers during human bone formation onto osteoblasts are composed of CaCO3. Those bioseeds are enzymatically formed via carbonic…”
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Effect of bioglass on growth and biomineralization of SaOS-2 cells in hydrogel after 3D cell bioprinting by Wang, Xiaohong, Tolba, Emad, Schröder, Heinz C, Neufurth, Meik, Feng, Qingling, Diehl-Seifert, Bärbel, Müller, Werner E G

“…We investigated the effect of bioglass (bioactive glass) on growth and mineralization of bone-related SaOS-2 cells, encapsulated into a printable and…”
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Amorphous Ca²⁺ polyphosphate nanoparticles regulate the ATP level in bone-like SaOS-2 cells by Müller, Werner E G, Tolba, Emad, Feng, Qingling, Schröder, Heinz C, Markl, Julia S, Kokkinopoulou, Maria, Wang, Xiaohong

“…Polyphosphate (polyP) is a physiologically occurring polyanion that is synthesized especially in bone-forming osteoblast cells and blood platelets. We used…”
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Isoquercitrin and polyphosphate co-enhance mineralization of human osteoblast-like SaOS-2 cells via separate activation of two RUNX2 cofactors AFT6 and Ets1 by Wang, Xiaohong, Schröder, Heinz C., Feng, Qingling, Diehl-Seifert, Bärbel, Grebenjuk, Vladislav A., Müller, Werner E.G.

“…Isoquercitrin, a dietary phytoestrogen, is a potential stimulator of bone mineralization used for prophylaxis of osteoporotic disorders. Here we studied the…”
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Biomimetic Alginate/Gelatin Cross-Linked Hydrogels Supplemented with Polyphosphate for Wound Healing Applications by Wang, Shunfeng, Wang, Xiaohong, Neufurth, Meik, Tolba, Emad, Schepler, Hadrian, Xiao, Shichu, Schröder, Heinz C, Müller, Werner E G

“…In the present study, the fabrication of a biomimetic wound dressing that mimics the extracellular matrix, consisting of a hydrogel matrix composed of…”
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Inorganic polymeric phosphate/polyphosphate as an inducer of alkaline phosphatase and a modulator of intracellular Ca²⁺ level in osteoblasts (SaOS-2 cells) in vitro by Müller, Werner E.G, Wang, Xiaohong, Diehl-Seifert, Bärbel, Kropf, Klaus, Schloßmacher, Ute, Lieberwirth, Ingo, Glasser, Gunnar, Wiens, Matthias, Schröder, Heinz C

“…Inorganic polymeric phosphate is a physiological polymer that accumulates in bone cells. In the present study osteoblast-like SaOS-2 cells were exposed to this…”
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Morphogenetic (Mucin Expression) as Well as Potential Anti-Corona Viral Activity of the Marine Secondary Metabolite Polyphosphate on A549 Cells by Müller, Werner E G, Neufurth, Meik, Wang, Shunfeng, Tan, Rongwei, Schröder, Heinz C, Wang, Xiaohong

“…The mucus layer of the nasopharynx and bronchial epithelium has a barrier function against inhaled pathogens such as the coronavirus SARS-CoV-2. We recently…”
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Silicateins-A Novel Paradigm in Bioinorganic Chemistry: Enzymatic Synthesis of Inorganic Polymeric Silica by Müller, Werner E. G., Schröder, Heinz C., Burghard, Zaklina, Pisignano, Dario, Wang, Xiaohong

“…The inorganic matrix of the siliceous skeletal elements of sponges, that is, spicules, is formed of amorphous biosilica. Until a decade ago, it remained…”
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Nanoparticle-directed and ionically forced polyphosphate coacervation: a versatile and reversible core–shell system for drug delivery by Müller, Werner E. G., Tolba, Emad, Wang, Shunfeng, Neufurth, Meik, Lieberwirth, Ingo, Ackermann, Maximilian, Schröder, Heinz C., Wang, Xiaohong

“…A drug encapsulation/delivery system using a novel principle is described that is based on an intra-particle migration of calcium ions between a central Ca 2+…”
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Cell migration, DNA fragmentation and antibacterial properties of novel silver doped calcium polyphosphate nanoparticles by Ekram, Basma, Tolba, Emad, El-Sayed, Ahmed F., Müller, Werner E. G., Schröder, Heinz C., Wang, Xiaohong, Abdel-Hady, Bothaina M.

“…To combat infections, silver was used extensively in biomedical field but there was a need for a capping agent to eliminate its cytotoxic effects. In this…”
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The Physiological Inorganic Polymers Biosilica and Polyphosphate as Key Drivers for Biomedical Materials in Regenerative Nanomedicine by Müller, Werner E G, Neufurth, Meik, Wang, Shunfeng, Schröder, Heinz C, Wang, Xiaohong

“…There is a need for novel nanomaterials with properties not yet exploited in regenerative nanomedicine. Based on lessons learned from the oldest metazoan…”
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The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor by Müller, Werner E G, Neufurth, Meik, Schepler, Hadrian, Wang, Shunfeng, Tolba, Emad, Schröder, Heinz C, Wang, Xiaohong

“…The effect of the polyanionic polymer of inorganic polyphosphate (polyP) involved in innate immunity on the binding of the receptor-binding domain (RBD) of the…”
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The role of biosilica in the osteoprotegerin/RANKL ratio in human osteoblast-like cells by Wiens, Matthias, Wang, Xiaohong, Schröder, Heinz C, Kolb, Ute, Schloßmacher, Ute, Ushijima, Hiroshi, Müller, Werner E.G

“…Abstract Earlier studies have demonstrated that biosilica, synthesized by the enzyme silicatein, induces hydroxyapatite formation in osteoblast-like SaOS-2…”
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