Search Results - "Schröder, Markus"
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Genefu: an R/Bioconductor package for computation of gene expression-based signatures in breast cancer
Published in Bioinformatics (01-04-2016)“…Breast cancer is one of the most frequent cancers among women. Extensive studies into the molecular heterogeneity of breast cancer have produced a plethora of…”
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survcomp: an R/Bioconductor package for performance assessment and comparison of survival models
Published in Bioinformatics (15-11-2011)“…The survcomp package provides functions to assess and statistically compare the performance of survival/risk prediction models. It implements state-of-the-art…”
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3
Multiple Origins of the Pathogenic Yeast Candida orthopsilosis by Separate Hybridizations between Two Parental Species
Published in PLoS genetics (02-11-2016)“…Mating between different species produces hybrids that are usually asexual and stuck as diploids, but can also lead to the formation of new species. Here, we…”
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PnB Designer: a web application to design prime and base editor guide RNAs for animals and plants
Published in BMC bioinformatics (02-03-2021)“…The rapid expansion of the CRISPR toolbox through tagging effector domains to either enzymatically inactive Cas9 (dCas9) or Cas9 nickase (nCas9) has led to…”
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Genus-Wide Comparative Genomics of Malassezia Delineates Its Phylogeny, Physiology, and Niche Adaptation on Human Skin
Published in PLoS genetics (01-11-2015)“…Malassezia is a unique lipophilic genus in class Malasseziomycetes in Ustilaginomycotina, (Basidiomycota, fungi) that otherwise consists almost exclusively of…”
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Comparative phenotypic analysis of the major fungal pathogens Candida parapsilosis and Candida albicans
Published in PLoS pathogens (01-09-2014)“…Candida parapsilosis and Candida albicans are human fungal pathogens that belong to the CTG clade in the Saccharomycotina. In contrast to C. albicans,…”
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The coupling of the hydrated proton to its first solvation shell
Published in Nature communications (18-10-2022)“…The Zundel ( H 5 O 2 + ) and Eigen ( H 9 O 4 + ) cations play an important role as intermediate structures for proton transfer processes in liquid water. In…”
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Bassoon Specifically Controls Presynaptic P/Q-type Ca2+ Channels via RIM-Binding Protein
Published in Neuron (Cambridge, Mass.) (01-04-2014)“…Voltage-dependent Ca2+channels (CaVs) represent the principal source of Ca2+ions that trigger evoked neurotransmitter release from presynaptic boutons…”
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Comparative genome analysis and gene finding in Candida species using CGOB
Published in Molecular biology and evolution (01-06-2013)“…The Candida Gene Order Browser (CGOB) was developed as a tool to visualize and analyze synteny relationships in multiple Candida species, and to provide an…”
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10
On the human consumption of the red seaweed dulse (Palmaria palmata (L.) Weber & Mohr)
Published in Journal of applied phycology (01-12-2013)“…The red seaweed dulse (Palmaria palmata) is one of the more popular seaweed species for human consumption in the Western world. With a documented historical…”
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The GenomeAsia 100K Project enables genetic discoveries across Asia
Published in Nature (London) (01-12-2019)“…The underrepresentation of non-Europeans in human genetic studies so far has limited the diversity of individuals in genomic datasets and led to reduced…”
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State-resolved infrared spectrum of the protonated water dimer: revisiting the characteristic proton transfer doublet peak
Published in Chemical science (Cambridge) (28-09-2022)“…The infrared (IR) spectra of protonated water clusters encode precise information on the dynamics and structure of the hydrated proton. However, the strong…”
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Identification of Non-Coding RNAs in the Candida parapsilosis Species Group
Published in PloS one (01-09-2016)“…The Candida CTG clade is a monophyletic group of fungal species that translates CTG as serine, and includes the pathogens Candida albicans and Candida…”
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High-Dimensional Quantum Dynamics Study on Excitation-Specific Surface Scattering Including Lattice Effects of a Five-Atom Surface Cell
Published in Journal of chemical theory and computation (11-05-2021)“…In this work, high-dimensional (21D) quantum dynamics calculations on the mode-specific surface scattering of a carbon monoxide molecule on a copper(100)…”
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15
Epitope-engineered human hematopoietic stem cells are shielded from CD123-targeted immunotherapy
Published in The Journal of experimental medicine (04-12-2023)“…Targeted eradication of transformed or otherwise dysregulated cells using monoclonal antibodies (mAb), antibody-drug conjugates (ADC), T cell engagers (TCE),…”
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Sodium butyrate protects mice from the development of the early signs of non-alcoholic fatty liver disease: role of melatonin and lipid peroxidation
Published in British journal of nutrition (28-11-2016)“…Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases worldwide with universally accepted treatments still lacking. Oral…”
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The Indian cobra reference genome and transcriptome enables comprehensive identification of venom toxins
Published in Nature genetics (01-01-2020)“…Snakebite envenoming is a serious and neglected tropical disease that kills ~100,000 people annually. High-quality, genome-enabled comprehensive…”
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Investigation of unsaponifiable matter of plant oils and isolation of eight phytosterols by means of high-speed counter-current chromatography
Published in Journal of Chromatography A (11-05-2012)“…► The unsaponifiable matter of rapeseed, olive and linseed oil was thoroughly analyzed by HSCCC. ► The HSCCC was operated in normal phase mode (tail-to-head)…”
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Recursive Editing improves homology-directed repair through retargeting of undesired outcomes
Published in Nature communications (05-08-2022)“…CRISPR-Cas induced homology-directed repair (HDR) enables the installation of a broad range of precise genomic modifications from an exogenous donor template…”
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Effect of progesterone on Candida albicans biofilm formation under acidic conditions: A transcriptomic analysis
Published in International journal of medical microbiology (01-04-2020)“…Vulvovaginal candidiasis (VVC) caused by Candida albicans is a common disease worldwide. A very important C. albicans virulence factor is its ability to form…”
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