Search Results - "Schriefer, Albert"

Serial Quantitative PCR Assay for Detection, Species Discrimination, and Quantification of Leishmania spp. in Human Samples by WEIRATHER, Jason L, JERONIMO, Selma M. B, DONELSON, John E, WILSON, Mary E, GAUTAM, Shalini, SUNDAR, Shyam, KANG, Mitchell, KURTZ, Melissa A, HAQUE, Rashidul, SCHRIEFER, Albert, TALHARI, Sinesio, CARVALHO, Edgar M

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Miltefosine in the treatment of cutaneous leishmaniasis caused by Leishmania braziliensis in Brazil: a randomized and controlled trial by Machado, Paulo R, Ampuero, Julia, Guimarães, Luiz H, Villasboas, Leonardo, Rocha, Ana T, Schriefer, Albert, Sousa, Rosana S, Talhari, Anette, Penna, Gerson, Carvalho, Edgar M

“…Cutaneous leishmaniasis (CL) is treated with parenteral drugs for decades with decreasing rate cures. Miltefosine is an oral medication with anti-leishmania…”
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Atypical Manifestations of Cutaneous Leishmaniasis in a Region Endemic for Leishmania braziliensis: Clinical, Immunological and Parasitological Aspects by Guimarães, Luiz Henrique, Queiroz, Adriano, Silva, Juliana A, Silva, Silvana C, Magalhães, Viviane, Lago, Ednaldo L, Machado, Paulo Roberto L, Bacellar, Olívia, Wilson, Mary E, Beverley, Stephen M, Carvalho, Edgar M, Schriefer, Albert

“…Atypical cutaneous leishmaniasis (ACL) has become progressively more frequent in Corte de Pedra, Northeast Brazil. Herein we characterize clinical…”
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Association between an Emerging Disseminated form of Leishmaniasis and Leishmania (Viannia) braziliensis Strain Polymorphisms by QUEIROZ, Adriano, SOUSA, Rosana, HEINE, Claudia, CARDOSO, Manuela, HENRIQUE GUIMARAES, Luiz, LIMA MACHADO, Paulo Roberto, CARVALHO, Edgar M, RILEY, Lee W, WILSON, Mary E, SCHRIEFER, Albert

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Leishmania braziliensis causing human disease in Northeast Brazil presents loci with genotypes in long-term equilibrium by Silva, Juliana A, Pinheiro, Ana Isabelle, Dourado, Maria Luiza, Medina, Lilian, Queiroz, Adriano, Guimarães, Luiz Henrique, Lessa, Marcus Miranda, Lago, Ednaldo L, Machado, Paulo Roberto L, Wilson, Mary E, Carvalho, Edgar M, Schriefer, Albert

“…Leishmaniases are neglected tropical diseases that inflict great burden to poor areas of the globe. Intense research has aimed to identify parasite genetic…”
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Clinical and histopathologic features of canine tegumentary leishmaniasis and the molecular characterization of Leishmania braziliensis in dogs by Lago, Jamile, Silva, Juliana A, Borja, Lairton, Fraga, Deborah B M, Schriefer, Albert, Arruda, Sergio, Lago, Ednaldo, Carvalho, Edgar M, Bacellar, Olívia

“…Cutaneous leishmaniasis (CL), caused by Leishmania braziliensis, is the most important presentation of tegumentary leishmaniasis (TL) in Latin American. While…”
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Dynamics of American tegumentary leishmaniasis in a highly endemic region for Leishmania (Viannia) braziliensis infection in northeast Brazil by Silva, Juliana, Queiroz, Adriano, Moura, Izabella, Sousa, Rosana S, Guimarães, Luiz Henrique, Machado, Paulo Roberto Lima, Lessa, Marcus, Lago, Ednaldo, Wilson, Mary E, Schriefer, Albert

“…American Tegumentary Leishmaniasis (ATL) caused by Leishmania braziliensis is endemic in Corte de Pedra, Northeast Brazil. Most L. braziliensis infections…”
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The gp63 Gene Cluster Is Highly Polymorphic in Natural Leishmania (Viannia) braziliensis Populations, but Functional Sites Are Conserved by Medina, Lilian S, Souza, Bruno Araújo, Queiroz, Adriano, Guimarães, Luiz Henrique, Lima Machado, Paulo Roberto, M Carvalho, Edgar, Wilson, Mary Edythe, Schriefer, Albert

“…GP63 or leishmanolysin is the major surface protease of Leishmania spp. involved in parasite virulence and host cell interaction. As such, GP63 is a potential…”
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The Influence of Infection by Different Leishmania (Viannia) braziliensis Isolates on the Pathogenesis of Disseminated Leishmaniasis by Oliveira, Walker N, Dórea, Andreza S, Carneiro, Pedro P, Nascimento, Maurício T, Carvalho, Lucas P, Machado, Paulo R L, Schriefer, Albert, Bacellar, Olívia, Carvalho, Edgar M

“…Disseminated Leishmaniasis (DL) is an emerging and severe form of infection defined by the presence of 10 and up to more than 1,000 skin lesions. The…”
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Detection of IgG Anti-Leishmania Antigen by Flow Cytometry as a Diagnostic Test for Cutaneous Leishmaniasis by Pedral-Sampaio, Geraldo, Alves, Jessé S, Schriefer, Albert, Magalhães, Andréa, Meyer, Roberto, Glesby, Marshall J, Carvalho, Edgar M, Carvalho, Lucas P

“…Diagnosis of cutaneous leishmaniasis (CL) relies on clinical presentation, parasite isolation, histopathologic evaluation and positive Montenegro skin test…”
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Up-Regulation of Th1-Type Responses in Mucosal Leishmaniasis Patients by BACELLAR, Olivia, LESSA, Helio, SCHRIEFER, Albert, MACHADO, Paulo, RIBEIRO DE JESUS, Amélia, DUTRA, Walderez O, GOLLOB, Kenneth J, CARVALHO, Edgar M

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Early Suppression of Macrophage Gene Expression by Leishmania braziliensis by Sousa, Rosana, Andrade, Viviane M, Bair, Thomas, Ettinger, Nicholas A, Guimarães, Luana, Andrade, Laura, Guimarães, Luiz H, Machado, Paulo R L, Carvalho, Edgar M, Wilson, Mary E, Schriefer, Albert

“…is an intracellular parasite that resides mostly in macrophages. Both the parasite genome and the clinical disease manifestations show considerable…”
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Decreased In Situ Expression of Interleukin-10 Receptor Is Correlated with the Exacerbated Inflammatory and Cytotoxic Responses Observed in Mucosal Leishmaniasis by Faria, Daniela R, Gollob, Kenneth J, Barbosa, José, Schriefer, Albert, Machado, Paulo R. L, Lessa, Hélio, Carvalho, Lucas P, Romano-Silva, Marco Aurélio, Jesus, Amélia R. de, Carvalho, Edgar M, Dutra, Walderez O

“…Human infection with Leishmania braziliensis can lead to cutaneous leishmaniasis (CL) or mucosal leishmaniasis (ML). We hypothesize that the intense tissue…”
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Investigation of the pathways related to intrinsic miltefosine tolerance in Leishmania (Viannia) braziliensis clinical isolates reveals differences in drug uptake by Espada, Caroline R., Magalhães, Rubens M., Cruz, Mario C., Machado, Paulo R., Schriefer, Albert, Carvalho, Edgar M., Hornillos, Valentín, Alves, João M., Cruz, Angela K., Coelho, Adriano C., Uliana, Silvia R.B.

“…In Brazil, cutaneous leishmaniasis is caused predominantly by L. (V.) braziliensis. The few therapeutic drugs available exhibit several limitations, mainly…”
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Forecasting temporal dynamics of cutaneous leishmaniasis in Northeast Brazil by Lewnard, Joseph A, Jirmanus, Lara, Júnior, Nivison Nery, Machado, Paulo R, Glesby, Marshall J, Ko, Albert I, Carvalho, Edgar M, Schriefer, Albert, Weinberger, Daniel M

“…Cutaneous leishmaniasis (CL) is a vector-borne disease of increasing importance in northeastern Brazil. It is known that sandflies, which spread the causative…”
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Leishmania -Induced Dendritic Cell Migration and Its Potential Contribution to Parasite Dissemination by Rebouças, Amanda, Silva, Thaílla S, Medina, Lilian S, Paredes, Bruno D, Aragão, Luciana S, Souza, Bruno S F, Borges, Valéria M, Schriefer, Albert, Veras, Patricia S T, Brodskyn, Claudia I, de Menezes, Juliana P B

“…, an intracellular parasite species, causes lesions on the skin and in the mucosa and internal organs. The dissemination of infected host cells containing is…”
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Geographic clustering of leishmaniasis in northeastern Brazil by Schriefer, Albert, Guimarães, Luiz H, Machado, Paulo R L, Lessa, Marcus, Lessa, Hélio A, Lago, Ednaldo, Ritt, Guilherme, Góes-Neto, Aristóteles, Schriefer, Ana L F, Riley, Lee W, Carvalho, Edgar M

“…To determine whether disease outcomes and clades of Leishmania braziliensis genotypes are associated, we studied geographic clustering of clades and most…”
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Molecular epidemiology of hepatitis B and hepatitis delta viruses circulating in the Western Amazon region, North Brazil by Crispim, Myuki Alfaia Esashika, Fraiji, Nelson Abrahim, Campello, Sonia Cordeiro, Schriefer, Nicolaus Albert, Stefani, Mariane Martins Araújo, Kiesslich, Dagmar

“…Hepatitis B virus (HBV) and hepatitis D virus (HDV) represent important public health problems in the Western Amazon region with reported cases of fulminant…”
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Differential effects of antigens from L. braziliensis isolates from disseminated and cutaneous leishmaniasis on in vitro cytokine production by Leopoldo, Paulo T G, Machado, Paulo R L, Almeida, Roque P, Schriefer, Albert, Giudice, Angela, de Jesus, Amélia Ribeiro, Ho, John L, Guimarães, Luiz Henrique, Bacellar, Olívia, Carvalho, Edgar M

“…Disseminated leishmaniasis is an emerging infectious disease, mostly due to L. braziliensis, which has clinical and histopathological features distinct from…”
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Frequency of Infection of Lutzomyia Phlebotomines with Leishmania braziliensis in a Brazilian Endemic Area as Assessed by Pinpoint Capture and Polymerase Chain Reaction by Miranda, J C, Reis, E, Schriefer, A, Goncalves, M, Reis, M G, Carvalho, L, Fernandes, O, Barral-Netto, M, Barral, A

“…Leishmania infected of Lutzomyia spp. are rare in endemic areas. We tested the hypothesis that there is clustering of infected vectors by combining pinpoint…”
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