Search Results - "Schreurs, Renée R. C. E."

Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine by Sagebiel, Adrian F., Steinert, Fenja, Lunemann, Sebastian, Körner, Christian, Schreurs, Renée R. C. E., Altfeld, Marcus, Perez, Daniel, Reinshagen, Konrad, Bunders, Madeleine J.

“…Innate lymphoid cells (ILC), including natural killer (NK) cells, are implicated in host-defense and tissue-growth. However, the composition and kinetics of NK…”
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Autophagy-enhancing ATG16L1 polymorphism is associated with improved clinical outcome and T-cell immunity in chronic HIV-1 infection by Schreurs, Renée R. C. E., Koulis, Athanasios, Booiman, Thijs, Boeser-Nunnink, Brigitte, Cloherty, Alexandra P. M., Rader, Anusca G., Patel, Kharishma S., Kootstra, Neeltje A., Ribeiro, Carla M. S.

“…Chronic HIV-1 infection is characterized by T-cell dysregulation that is partly restored by antiretroviral therapy. Autophagy is a critical regulator of T-cell…”
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Autophagy-enhancing drugs limit mucosal HIV-1 acquisition and suppress viral replication ex vivo by Cloherty, Alexandra P. M., van Teijlingen, Nienke H., Eisden, Tracy-Jane T. H. D., van Hamme, John L., Rader, Anusca G., Geijtenbeek, Teunis B. H., Schreurs, Renée R. C. E., Ribeiro, Carla M. S.

“…Current direct-acting antiviral therapies are highly effective in suppressing HIV-1 replication. However, mucosal inflammation undermines prophylactic…”
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Berbamine suppresses intestinal SARS-CoV-2 infection via a BNIP3-dependent autophagy blockade by Cloherty, Alexandra P. M., Rader, Anusca G., Patel, Kharishma S., Pérez-Vargas, Jimena, Thompson, Connor A. H., Ennis, Siobhan, Niikura, Masahiro, Wildenberg, Manon E., Muncan, Vanesa, Schreurs, Renée R. C. E., Jean, François, Ribeiro, Carla M. S.

“…SARS-CoV-2, the causative virus of COVID-19, continues to threaten global public health. COVID-19 is a multi-organ disease, causing not only respiratory…”
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Dengue virus exploits autophagy vesicles and secretory pathways to promote transmission by human dendritic cells by Cloherty, Alexandra P M, Rader, Anusca G, Patel, Kharishma S, Eisden, Tracy-Jane T H D, van Piggelen, Sterre, Schreurs, Renée R C E, Ribeiro, Carla M S

“…Dengue virus (DENV), transmitted by infected mosquitoes, is a major public health concern, with approximately half the world's population at risk for…”
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Enhanced Th17 responses in the appendix of children with complex compared to simple appendicitis are associated with microbial dysbiosis by The, Sarah-May M L, Schreurs, Renée R C E, Drewniak, Agata, Bakx, Roel, de Meij, Tim G J, Budding, Andries E, Poort, Linda, Cense, Huib A, Heij, Hugo A, van Heurn, L W Ernest, Gorter, Ramon R, Bunders, Madeleine J

“…Appendicitis is one of the most common causes of acute abdominal surgery in children. The clinical course of appendicitis ranges from simple to complex…”
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CXCR5+PD-1++ CD4+ T cells colonize infant intestines early in life and promote B cell maturation by Jordan-Paiz, Ana, Martrus, Glòria, Steinert, Fenja L., Kaufmann, Max, Sagebiel, Adrian F., Schreurs, Renée R. C. E., Rechtien, Anne, Baumdick, Martin E., Jung, Johannes M., Möller, Kimberly J., Wegner, Lucy, Grüttner, Cordula, Richert, Laura, Thünauer, Roland, Schroeder-Schwarz, Jennifer, van Goudoever, Johannes B., Geijtenbeek, Teunis B. H., Altfeld, Marcus, Pals, Steven T., Perez, Daniel, Klarenbeek, Paul L., Tomuschat, Christian, Sauter, Guido, Königs, Ingo, Schumacher, Udo, Friese, Manuel A., Melling, Nathaniel, Reinshagen, Konrad, Bunders, Madeleine J.

“…Gastrointestinal infections are a major cause for serious clinical complications in infants. The induction of antibody responses by B cells is critical for…”
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Expanded ILC2s in human infant intestines promote tissue growth by Möller, Kimberly J., Wegner, Lucy H.M., Malsy, Jakob, Baumdick, Martin E., Borggrewe, Malte, Jordan-Paiz, Ana, Jung, Johannes M., Martrus, Glòria, Kretschmer, Paul, Sagebiel, Adrian F., Schreurs, Renée R.C.E., Hagen, Sven H., Burmester, Gunter, Clauditz, Till S., Pals, Steven T., Boettcher, Michael, Melling, Nathaniel, Sauter, Guido, Tomuschat, Christian, Königs, Ingo, Schumacher, Udo, Altfeld, Marcus, Bernink, Jochem H., Perez, Daniel, Reinshagen, Konard, Bunders, Madeleine J.

“…[Display omitted] Early life is characterized by extraordinary challenges, including rapid tissue growth and immune adaptation to foreign antigens after birth…”
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In vitro co-culture of human intestinal organoids and lamina propria-derived CD4+ T cells by Schreurs, Renée R.C.E., Baumdick, Martin E., Drewniak, Agata, Bunders, Madeleine J.

“…Crosstalk between immune cells and intestinal stem cells (ISCs) in vivo plays a critical role in tissue homeostasis and inflammation; however, in vitro models…”
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Human Fetal TNF-α-Cytokine-Producing CD4+ Effector Memory T Cells Promote Intestinal Development and Mediate Inflammation Early in Life by Schreurs, Renée R.C.E., Baumdick, Martin E., Sagebiel, Adrian F., Kaufmann, Max, Mokry, Michal, Klarenbeek, Paul L., Schaltenberg, Nicola, Steinert, Fenja L., van Rijn, Jorik M., Drewniak, Agata, The, Sarah-May M.L., Bakx, Roel, Derikx, Joep P.M., de Vries, Niek, Corpeleijn, Willemijn E., Pals, Steven T., Gagliani, Nicola, Friese, Manuel A., Middendorp, Sabine, Nieuwenhuis, Edward E.S., Reinshagen, Konrad, Geijtenbeek, Teunis B.H., van Goudoever, Johannes B., Bunders, Madeleine J.

“…Although the fetal immune system is considered tolerogenic, preterm infants can suffer from severe intestinal inflammation, including necrotizing enterocolitis…”
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HIV‐1 exposure and immune activation enhance sexual transmission of Hepatitis C virus by primary Langerhans cells by Nijmeijer, Bernadien M, Sarrami‐Forooshani, Ramin, Steba, Gaby S, Schreurs, Renée RCE, Koekkoek, Sylvie M, Molenkamp, Richard, Schinkel, Janke, Reiss, Peter, Siegenbeek van Heukelom, Matthijs L, Valk, Marc, Ribeiro, Carla MS, Geijtenbeek, Teunis BH

“…Introduction The significant rise in incidence of Hepatitis C virus (HCV) infection among men‐who‐have‐sex‐with‐men (MSM) living with HIV‐1 suggests that HCV…”
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