Search Results - "Schretlen, E D"

Morphology and incidence of the "posttherapeutic lymphoid cell" in the bone marrow of children with acute lymphoblastic leukemia by Schuurmans Stekhoven, JH, Langenhuysen, CA, Bakkeren, JA, Holland, R, Holler, I, De Vaan, GA, Schretlen, ED

“…In the posttherapeutic bone marrow of a group of 30 children with acute lymphoblastic leukemia (ALL), small numbers of a particular lymphoid cell with a…”
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6-mercaptopurine: pharmacokinetics in animals and preliminary results in children by Schouten, T J, De Abreu, R A, De Bruyn, C H, Van der Kleijn, E, Oosterbaan, M J, Schretlen, E D, De Vaan, G A

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6-Mercaptopurine: high-dose 24-h infusions in goats by SCHOUTEN, T. J, DE ABREU, R. A, SCHRETLEN, E. D. A. M, VANBAAL, J. M, VAN LEEUWEN, M. B, DEVAAN, G. A. M

“…In vitro investigations have indicated the need for both prolonged exposure to 6-mercaptopurine (6MP) and the use of high concentrations to achieve maximal…”
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Citrullinaemia with Rapidly Fatal Neonatal Course by Van Der Zee, S. P. M., Trijbels, J. M. F., Monnens, L. A. H., Hommes, F. A., Schretlen, E. D. A. M.

“…An infant with a deficiency of argininosuccinate synthetase in liver and brain developed rapidly increasing apathy, respiratory insufficiency, and convulsions…”
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Megaloblastic anaemia in the Lesch-Nyhan syndrome by van der Zee, S P, Schretlen, E D, Monnens, L A

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6-Mercaptopurine: total body autoradiograms and plasma concentration-time curves of 6MP and metabolites from marmoset monkeys by Schouten, T J, De Abreu, R A, Schretlen, E D, de Vaan, G A, van der Kleijn, E

“…To study the body distribution of 6-mercaptopurine (6MP), [8-14C]6MP was given by infusion to 2 marmoset monkeys at a dose rate of 5 mg/kg body weight/h for 1…”
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A patient with nonketotic hyperglycinemia: biochemical findings and therapeutic approaches by Trijbels, J M, Monnens, L A, van der Zee, S P, Vrenken, J A, Sengers, R C, Schretlen, E D

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The IMP dehydrogenase catalysed reaction in erythrocytes of normal individuals and patients with hypoxanthine guanine phosphoribosyltransferase deficiency by Lommen, E J, de Abreu, R A, Trijbels, J M, Schretlen, E D

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Effects of methotrexate on purine and pyrimidine metabolism and cell-kinetic parameters in human malignant lymphoblasts of different lineages by Bökkerink, J P, De Abreu, R A, Bakker, M A, Hulscher, T W, van Baal, J M, Schretlen, E D, De Bruijn, C H

“…MOLT-4 (T-), RAJI (B-), and KM-3 (non-B-non-T-, common ALL) malignant lymphoblasts demonstrated significant differences in their activities of purine de novo…”
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Sideroblastic anaemia. A review of seven paediatric cases by Hamel, B C, Schretlen, E D

“…Sideroblastic Anaemias are characterised by a) chronic hypochromic anemia, b) ringed sideroblasts in the bone marrow, c) an increase in total body iron, d)…”
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Synergy of methotrexate and 6-mercaptopurine on cell growth and clonogenicity of cultured human T-lymphoblasts by De Abreu, R A, Bökkerink, J P, Bakker, M A, Hulscher, T W, de Vaan, G A, de Bruijn, C H, Schretlen, E D

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Increased availability of phosphoribosyl pyrophosphate as the basis for enhanced 6-mercaptopurine incorporation by methotrexate, in cultured human lymphoblasts by Bökkerink, J P, de Abreu, R A, van Laarhoven, J P, Bakker, M A, Hulscher, T W, Schretlen, E D, de Bruijn, C H

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Enzymes of purine interconversions in subfractions of lymphocytes by van Laarhoven, J P, Spierenburg, G T, de Bruyn, C H, Schretlen, E D

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Influence of methotrexate on purine and pyrimidine pools and on cell phase distribution of cultured human lymphoblasts by De Abreu, R A, Bökkerink, J P, Bakker, M A, Hulscher, T W, van Baal, J M, de Bruijn, C H, Schretlen, E D

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Purine metabolism in childhood acute lymphoblastic leukemia: biochemical markers for diagnosis and chemotherapy by van Laarhoven, J P, Spierenburg, G T, Bakkeren, J A, Schouten, T J, De Bruyn, C H, Geerts, S J, Schretlen, E D

“…Adenosine deaminase (ADA), purine nucleoside phosphorylase (PNP), 5'nucleotidase (5'NT), ecto-5'NT, hypoxanthine-guanine phosphoribosyltransferase(HGPRT),…”
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Haemolytic-uraemic syndrome. Epidemiological and clinical study by van Wieringen, P M, Monnens, L A, Schretlen, E D

“…Between January 1965 and December 1970, 212 patients with the haemolytic-uraemic syndrome in the Netherlands were analysed in an epidemiological and clinical…”
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6-thioguanine: high-dose 2-H infusions in goats by SCHOUTEN, T. J, DE ABREU, R. A, SCHRETLEN, E. D. A. M, VAN LEEUWEN, M. B, VAN BAAL, J. M, DE VAAN, G. A. M

“…6-Thioguanine (6TG) is poorly absorbed after oral administration. Bolus injections of 6TG result in high peak concentrations with relatively short-lived plasma…”
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Haemolytic-uraemic syndrome by van Wieringen, P. M. V., Monnens, L. A. H., Schretlen, E. D. A. M.

“…Between January 1965 and December 1970, 212 patients with the haemolytic-uraemic syndrome in the Netherlands were analysed in an epidemiological and clinical…”
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Comparison of CNS-leukaemia in children with acute leukaemia, induced either with rubidomycin or L-asparaginase by de Vaan, G A, Marcar, J R, Schretlen, E D

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Glucosephosphate isomerase deficiency, a new variant in a Dutch family. Case report by Rotteveel, J J, de Vaan, G A, Staal, G E, van Biervliet, J P, Schretlen, E D

“…The clinical course and the biochemical findings are reported from a patient suffering from glucosephosphate isomerase (G.P.I EC 5.3.1.9) deficiency type…”
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