Search Results - "Schrenk, Sandra"

A transcription factor is the target of propranolol treatment in infantile hemangioma by Schrenk, Sandra, Boscolo, Elisa

“…Propranolol is a nonselective β-adrenergic receptor (AR) blocker that has been the first-line therapy for problematic infantile hemangioma (IH), the most…”
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Constitutive Active Mutant TIE2 Induces Enlarged Vascular Lumen Formation with Loss of Apico-basal Polarity and Pericyte Recruitment by Cai, Yuqi, Schrenk, Sandra, Goines, Jillian, Davis, George E., Boscolo, Elisa

“…Abnormalities in controlling key aspects of angiogenesis including vascular cell migration, lumen formation and vessel maturation are hallmarks of vascular…”
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MEK inhibition reduced vascular tumor growth and coagulopathy in a mouse model with hyperactive GNAQ by Schrenk, Sandra, Bischoff, Lindsay J., Goines, Jillian, Cai, Yuqi, Vemaraju, Shruti, Odaka, Yoshinobu, Good, Samantha R., Palumbo, Joseph S., Szabo, Sara, Reynaud, Damien, Van Raamsdonk, Catherine D., Lang, Richard A., Boscolo, Elisa

“…Activating non-inherited mutations in the guanine nucleotide-binding protein G(q) subunit alpha (GNAQ) gene family have been identified in childhood vascular…”
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Anti-inflammatory activity of Wnt signaling in enteric nervous system: in vitro preliminary evidences in rat primary cultures by Di Liddo, Rosa, Bertalot, Thomas, Schuster, Anne, Schrenk, Sandra, Tasso, Alessia, Zanusso, Ilenia, Conconi, Maria Teresa, Schäfer, Karl Herbert

“…In the last years, Wnt signaling was demonstrated to regulate inflammatory processes. In particular, an increased expression of Wnts and Frizzled receptors was…”
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STW 5 Herbal Preparation Modulates Wnt3a and Claudin 1 Gene Expression in Zebrafish IBS-like Model by Piccione, Monica, Facchinello, Nicola, Schrenk, Sandra, Gasparella, Marco, Pathak, Surajit, Ammar, Ramy M, Rabini, Sabine, Dalla Valle, Luisa, Di Liddo, Rosa

“…Irritable bowel syndrome (IBS) is a functional bowel disorder characterized by chronic abdominal pain and stool irregularities. STW 5 has proven clinical…”
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A transcription factor is the target of propranolol treatment in infantile hemangioma by Schrenk, Sandra, Boscolo, Elisa

“…Propranolol is a nonselective [beta]-adrenergic receptor (AR) blocker that has been the first-line therapy for problematic infantile hemangioma (IH), the most…”
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Protocol for three-dimensional whole-mount imaging of the vascular network in the intestinal muscle by Schrenk, Sandra, Bischoff, Lindsay J., Boscolo, Elisa

“…Three-dimensional (3D) imaging of vascular networks is essential for the investigation of vascular patterning and organization. Here, we present a step-by-step…”
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Structural and functional failure of fibrillin‑1 in human diseases (Review) by Schrenk, Sandra, Cenzi, Carola, Bertalot, Thomas, Conconi, Maria Teresa, Liddo, Rosa Di

“…Fibrillins (FBNs) are key relay molecules that form the backbone of microfibrils in elastic and non-elastic tissues. Interacting with other components of the…”
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Leucocyte and Platelet‐rich Fibrin: a carrier of autologous multipotent cells for regenerative medicine by Di Liddo, Rosa, Bertalot, Thomas, Borean, Alessio, Pirola, Ivan, Argentoni, Alberto, Schrenk, Sandra, Cenzi, Carola, Capelli, Stefano, Conconi, Maria Teresa, Parnigotto, Pier Paolo

“…The wound healing is a complex process wherein inflammation, proliferation and regeneration evolve according to a spatio‐temporal pattern from the activation…”
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NRASQ61R mutation in human endothelial cells causes vascular malformations by Boscolo, Elisa, Pastura, Patricia, Schrenk, Sandra, Goines, Jillian, Kang, Rachael, Pillis, Devin, Malik, Punam, Le Cras, Timothy D.

“…Somatic mutations in NRAS drive the pathogenesis of melanoma and other cancers but their role in vascular anomalies and specifically human endothelial cells is…”
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NRAS Q61R mutation in human endothelial cells causes vascular malformations by Boscolo, Elisa, Pastura, Patricia, Schrenk, Sandra, Goines, Jillian, Kang, Rachael, Pillis, Devin, Malik, Punam, Le Cras, Timothy D

“…Somatic mutations in NRAS drive the pathogenesis of melanoma and other cancers but their role in vascular anomalies and specifically human endothelial cells is…”
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Preliminary Discovery of Small Molecule Inhibitors of Epidermal Growth Factor Receptor (EGFR) That Bind to the Extracellular Domain by Di Liddo, Rosa, Verona, Marco, Vaccarin, Christian, Acquasaliente, Laura, Schrenk, Sandra, Piccione, Monica, Cenzi, Carola, De Franco, Michele, Dal Prà, Matteo, Ribaudo, Giovanni, Ferlin, Maria Grazia, Conconi, Maria Teresa, Chilin, Adriana, Gandin, Valentina, Marzaro, Giovanni

“…The Epidermal Growth Factor Receptor (EGFR) is a transmembrane glycoprotein belonging to the protein kinase superfamily. It is composed of an extracellular…”
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Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model by Di Liddo, Rosa, Valente, Sergio, Taurone, Samanta, Zwergel, Clemens, Marrocco, Biagina, Turchetta, Rosaria, Conconi, Maria Teresa, Scarpa, Carlotta, Bertalot, Thomas, Schrenk, Sandra, Mai, Antonello, Artico, Marco

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Maintenance of the enteric stem cell niche by bacterial lipopolysaccharides? Evidence and perspectives by Schuster, Anne, Klotz, Markus, Schwab, Tanja, Di Liddo, Rosa, Bertalot, Thomas, Schrenk, Sandra, Martin, Monika, Nguyen, The Duy, Nguyen, Thi Nha Quyen, Gries, Manuela, Faßbender, Klaus, Conconi, Maria Teresa, Parnigotto, Pier Paolo, Schäfer, Karl‐Herbert

“…The enteric nervous system (ENS) has to respond to continuously changing microenvironmental challenges within the gut and is therefore dependent on a neural…”
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Fluorescence-based gene reporter plasmid to track canonical Wnt signaling in ENS inflammation by Di Liddo, Rosa, Bertalot, Thomas, Schuster, Anne, Schrenk, Sandra, Müller, Oliver, Apfel, Johanna, Reischmann, Patricia, Rajendran, Senthilkumar, Sfriso, Riccardo, Gasparella, Marco, Parnigotto, Pier Paolo, Conconi, Maria Teresa, Schäfer, Karl Herbert

“…In several gut inflammatory or cancer diseases, cell-cell interactions are compromised, and an increased cytoplasmic expression of β-catenin is observed. Over…”
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Nanopatterned acellular valve conduits drive the commitment of blood-derived multipotent cells by Di Liddo, Rosa, Aguiari, Paola, Barbon, Silvia, Bertalot, Thomas, Mandoli, Amit, Tasso, Alessia, Schrenk, Sandra, Iop, Laura, Gandaglia, Alessandro, Parnigotto, Pier Paolo, Conconi, Maria Teresa, Gerosa, Gino

“…Considerable progress has been made in recent years toward elucidating the correlation among nanoscale topography, mechanical properties, and biological…”
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Vascular and neural stem cells in the gut: do they need each other? by Schrenk, Sandra, Schuster, Anne, Klotz, Markus, Schleser, Franziska, Lake, Jonathan, Heuckeroth, Robert O., Kim, Yoo-Jin, Laschke, Matthias W., Menger, Michael D., Schäfer, Karl-Herbert

“…Enteric neurons and blood vessels form intricate networks throughout the gastrointestinal tract. To support the hypothesis of a possible interaction of both…”
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Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model by Di Liddo, Rosa, Valente, Sergio, Taurone, Samanta, Zwergel, Clemens, Marrocco, Biagina, Turchetta, Rosaria, Conconi, Maria Teresa, Scarpa, Carlotta, Bertalot, Thomas, Schrenk, Sandra, Mai, Antonello, Artico, Marco

“…Among epigenetic enzymes, histone deacetylases (HDACs) are responsible for regulating the expression of an extensive array of genes by reversible deacetylation…”
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