Search Results - "Schreiner, Silke"

Exon Circularization Requires Canonical Splice Signals by Starke, Stefan, Jost, Isabelle, Rossbach, Oliver, Schneider, Tim, Schreiner, Silke, Hung, Lee-Hsueh, Bindereif, Albrecht

“…Circular RNAs (circRNAs), an abundant class of noncoding RNAs in higher eukaryotes, are generated from pre-mRNAs by circularization of adjacent exons. Using a…”
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CircRNA-protein complexes: IMP3 protein component defines subfamily of circRNPs by Schneider, Tim, Hung, Lee-Hsueh, Schreiner, Silke, Starke, Stefan, Eckhof , Heinrich, Rossbach, Oliver, Reich, Stefan, Medenbach, Jan, Bindereif , Albrecht

“…Circular RNAs (circRNAs) constitute a new class of noncoding RNAs in higher eukaryotes generated from pre-mRNAs by alternative splicing. Here we investigated…”
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DEAD-box ATPase Dbp2 is the key enzyme in an mRNP assembly checkpoint at the 3’-end of genes and involved in the recycling of cleavage factors by Aydin, Ebru, Schreiner, Silke, Böhme, Jacqueline, Keil, Birte, Weber, Jan, Žunar, Bojan, Glatter, Timo, Kilchert, Cornelia

“…mRNA biogenesis in the eukaryotic nucleus is a highly complex process. The numerous RNA processing steps are tightly coordinated to ensure that only fully…”
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Selective release of circRNAs in platelet-derived extracellular vesicles by Preußer, Christian, Hung, Lee-Hsueh, Schneider, Tim, Schreiner, Silke, Hardt, Martin, Moebus, Anna, Santoso, Sentot, Bindereif, Albrecht

“…Circular RNAs (circRNAs) are a novel class of noncoding RNAs present in all eukaryotic cells investigated so far and generated by a special mode of alternative…”
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Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3 by Schneider, Tim, Hung, Lee-Hsueh, Aziz, Masood, Wilmen, Anna, Thaum, Stephanie, Wagner, Jacqueline, Janowski, Robert, Müller, Simon, Schreiner, Silke, Friedhoff, Peter, Hüttelmaier, Stefan, Niessing, Dierk, Sattler, Michael, Schlundt, Andreas, Bindereif, Albrecht

“…How multidomain RNA-binding proteins recognize their specific target sequences, based on a combinatorial code, represents a fundamental unsolved question and…”
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Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage by Finzsch, Markus, Schreiner, Silke, Kichko, Tatjana, Reeh, Peter, Tamm, Ernst R, Bösl, Michael R, Meijer, Dies, Wegner, Michael

“…Mutations in the transcription factor SOX10 cause neurocristopathies, including Waardenburg-Hirschsprung syndrome and peripheral neuropathies in humans. This…”
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Activation of Krox20 gene expression by Sox10 in myelinating Schwann cells by Reiprich, Simone, Kriesch, Jana, Schreiner, Silke, Wegner, Michael

“…J. Neurochem. (2010) 112, 744-754. The high-mobility group domain transcription factor Sox10 is believed to influence myelination in Schwann cells by directly…”
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Auto- and Cross-Regulation of the hnRNP L Proteins by Alternative Splicing by Rossbach, Oliver, Hung, Lee-Hsueh, Schreiner, Silke, Grishina, Inna, Heiner, Monika, Hui, Jingyi, Bindereif, Albrecht

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Diverse roles of hnRNP L in mammalian mRNA processing: a combined microarray and RNAi analysis by Hung, Lee-Hsueh, Heiner, Monika, Hui, Jingyi, Schreiner, Silke, Benes, Vladimir, Bindereif, Albrecht

“…Alternative mRNA splicing patterns are determined by the combinatorial control of regulator proteins and their target RNA sequences. We have recently…”
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Crosslinking-immunoprecipitation (iCLIP) analysis reveals global regulatory roles of hnRNP L by Rossbach, Oliver, Hung, Lee-Hsueh, Khrameeva, Ekaterina, Schreiner, Silke, König, Julian, Curk, Tomaž, Zupan, Blaž, Ule, Jernej, Gelfand, Mikhail S, Bindereif, Albrecht

“…Heterogeneous nuclear ribonucleoprotein L (hnRNP L) is a multifunctional RNA-binding protein that is involved in many different processes, such as regulation…”
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HnRNP L and L-like cooperate in multiple-exon regulation of CD45 alternative splicing by Preussner, Marco, Schreiner, Silke, Hung, Lee-Hsueh, Porstner, Martina, Jäck, Hans-Martin, Benes, Vladimir, Rätsch, Gunnar, Bindereif, Albrecht

“…CD45 encodes a trans-membrane protein-tyrosine phosphatase expressed in diverse cells of the immune system. By combinatorial use of three variable exons 4-6,…”
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Intronic CA-repeat and CA-rich elements: a new class of regulators of mammalian alternative splicing by Hui, Jingyi, Hung, Lee-Hsueh, Heiner, Monika, Schreiner, Silke, Neumüller, Norma, Reither, Gregor, Haas, Stefan A, Bindereif, Albrecht

“…We have recently identified an intronic polymorphic CA‐repeat region in the human endothelial nitric oxide synthase (eNOS) gene as an important determinant of…”
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Hoxa9 and Meis1 Are Key Targets for MLL-ENL-Mediated Cellular Immortalization by Zeisig, Bernd B., Milne, Tom, García-Cuéllar, María-Paz, Schreiner, Silke, Martin, Mary-Ellen, Fuchs, Uta, Borkhardt, Arndt, Chanda, Sumit K., Walker, John, Soden, Richard, Hess, Jay L., Slany, Robert K.

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Hypomorphic Sox10 alleles reveal novel protein functions and unravel developmental differences in glial lineages by Schreiner, Silke, Cossais, François, Fischer, Kerstin, Scholz, Stefanie, Bösl, Michael R., Holtmann, Bettina, Sendtner, Michael, Wegner, Michael

“…The transcription factor Sox10 regulates early neural crest development, specification of neural crest-derived lineages and terminal differentiation of…”
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SoxE proteins are differentially required in mouse adrenal gland development by Reiprich, Simone, Stolt, C Claus, Schreiner, Silke, Parlato, Rosanna, Wegner, Michael

“…Sry-box (Sox)8, Sox9, and Sox10 are all strongly expressed in the neural crest. Here, we studied the influence of these closely related transcription factors…”
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Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence by Kellerer, Susanne, Schreiner, Silke, Stolt, C Claus, Scholz, Stefanie, Bösl, Michael R, Wegner, Michael

“…Sox8 and Sox10 are two closely related transcription factors of the Sox protein family with overlapping expression patterns during development. They are…”
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HnRNP L-mediated regulation of mammalian alternative splicing by interference with splice site recognition by Heiner, Monika, Hui, Jingyi, Schreiner, Silke, Hung, Lee-Hsueh, Bindereif, Albrecht

“…Heterogeneous nuclear ribonucleoprotein (hnRNP) L can regulate alternative mRNA splicing in diverse ways, binding to exonic or intronic sites and acting as…”
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Regulation of Boundary Cap Neural Crest Stem Cell Differentiation After Transplantation by Aldskogius, Hakan, Berens, Christian, Kanaykina, Nadezda, Liakhovitskaia, Anna, Medvinsky, Alexander, Sandelin, Martin, Schreiner, Silke, Wegner, Michael, Hjerling‐Leffler, Jens, Kozlova, Elena N.

“…Success of cell replacement therapies for neurological disorders will depend largely on the optimization of strategies to enhance viability and control the…”
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Human U4/U6 snRNP Recycling Factor p110: Mutational Analysis Reveals the Function of the Tetratricopeptide Repeat Domain in Recycling by Medenbach, Jan, Schreiner, Silke, Liu, Sunbin, Lührmann, Reinhard, Bindereif, Albrecht

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Design and application of circular RNAs with protein-sponge function by Schreiner, Silke, Didio, Anna, Hung, Lee-Hsueh, Bindereif, Albrecht

“…Abstract Circular RNAs (circRNAs) are a class of noncoding RNAs, generated from pre-mRNAs by circular splicing of exons and functionally largely…”
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