Search Results - "Schreiner, Patrick A."

PAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors by Searcy, Madeline B., Larsen, Randolph K., Stevens, Bradley T., Zhang, Yang, Jin, Hongjian, Drummond, Catherine J., Langdon, Casey G., Gadek, Katherine E., Vuong, Kyna, Reed, Kristin B., Garcia, Matthew R., Xu, Beisi, Kimbrough, Darden W., Adkins, Grace E., Djekidel, Nadhir, Porter, Shaina N., Schreiner, Patrick A., Pruett-Miller, Shondra M., Abraham, Brian J., Rehg, Jerold E., Hatley, Mark E.

“…Fusion-positive rhabdomyosarcoma (FP-RMS) driven by the expression of the PAX3-FOXO1 (P3F) fusion oncoprotein is an aggressive subtype of pediatric…”
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Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma identity by Langdon, Casey G., Gadek, Katherine E., Garcia, Matthew R., Evans, Myron K., Reed, Kristin B., Bush, Madeline, Hanna, Jason A., Drummond, Catherine J., Maguire, Matthew C., Leavey, Patrick J., Finkelstein, David, Jin, Hongjian, Schreiner, Patrick A., Rehg, Jerold E., Hatley, Mark E.

“…PTEN promoter hypermethylation is nearly universal and PTEN copy number loss occurs in ~25% of fusion-negative rhabdomyosarcoma (FN-RMS). Here we show Pten…”
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Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair by Aditi, Downing, Susanna M., Schreiner, Patrick A., Kwak, Young Don, Li, Yang, Shaw, Timothy I., Russell, Helen R., McKinnon, Peter J.

“…Aicardi-Goutières syndrome (AGS) is a monogenic type I interferonopathy characterized by neurodevelopmental defects and upregulation of type I interferon…”
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Abstract 1667: Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma identity by Langdon, Casey G., Gadek, Katherine E., Garcia, Matthew R., Evans, Myron K., Reed, Kristin B., Bush, Madeline, Hanna, Jason A., Drummond, Catherine J., Maguire, Matthew C., Leavey, Patrick J., Finkelstein, David, Jin, Hongjian, Schreiner, Patrick A., Rehg, Jerold E., Hatley, Mark E.

“…Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children with no improvements in treatment options for RMS patients over the past four…”
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A Genomic Exploration of Transposable Element and piRNA Occupancy, Abundance, and Functionality by Schreiner, Patrick A

“…The research herein aims to promote a better understanding of the occupancy, architecture, and diversity of transposable elements and piRNA clusters across…”
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