Search Results - "Schreiber, Veronika"
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Liver and pancreatic-targeted interleukin-22 as a therapeutic for metabolic dysfunction-associated steatohepatitis
Published in Nature communications (29-05-2024)“…Metabolic dysfunction-associated steatohepatitis (MASH) is the most prevalent cause of liver disease worldwide, with a single approved therapeutic. Previous…”
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Male infants are at higher risk of neonatal mortality and severe morbidity
Published in Australian & New Zealand journal of obstetrics & gynaecology (01-08-2023)“…Background While a male infant is usually born with a higher birthweight than his female counterpart, he is more at risk of variety of adverse perinatal…”
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Perinatal antecedents of moderate and severe neonatal hypoxic ischaemic encephalopathy: An Australian birth cohort study
Published in Australian & New Zealand journal of obstetrics & gynaecology (01-06-2023)“…Background Neonatal hypoxic ischaemic encephalopathy (HIE) is the most common cause of encephalopathy in the neonatal period and carries a high risk of…”
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Predictive utility of the fetal cerebroplacental ratio for hypoxic ischaemic encephalopathy, severe neonatal morbidity and perinatal mortality in late‐preterm and term infants
Published in Australian & New Zealand journal of obstetrics & gynaecology (01-08-2023)“…Aims The aim of this study was to evaluate the association of a low cerebroplacental ratio (CPR) with hypoxic ischaemic encephalopathy (HIE), severe neonatal…”
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High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22
Published in Scientific reports (28-06-2016)“…Prolonged high fat diets (HFD) induce low-grade chronic intestinal inflammation in mice, and diets high in saturated fat are a risk factor for the development…”
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Assessment of Long-Term Macrolide Exposure on the Oropharyngeal Microbiome and Macrolide Resistance in Healthy Adults and Consequences for Onward Transmission of Resistance
Published in Antimicrobial agents and chemotherapy (19-04-2022)“…While the use of long-term macrolide therapy to prevent exacerbations in chronic respiratory diseases is widespread, its impact on the oropharyngeal microbiota…”
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Improved concordance of challenging human epidermal growth factor receptor 2 dual in-situ hybridisation cases with the use of a digital image analysis algorithm in breast cancer
Published in Histopathology (01-10-2023)“…Accurate assessment of human epidermal growth factor receptor 2 (HER2) expression by HER2 immunohistochemistry and in-situ hybridisation (ISH) is critical for…”
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Interleukin-22 suppresses major histocompatibility complex II in mucosal epithelial cells
Published in The Journal of experimental medicine (06-11-2023)“…Major histocompatibility complex (MHC) II is dynamically expressed on mucosal epithelial cells and is induced in response to inflammation and parasitic…”
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Secreted NF-κB suppressive microbial metabolites modulate gut inflammation
Published in Cell reports (Cambridge) (12-04-2022)“…Emerging evidence suggests that microbiome-host crosstalk regulates intestinal immune activity and predisposition to inflammatory bowel disease (IBD). NF-κB is…”
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MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity
Published in Oncogene (28-11-2019)“…Many adenocarcinomas, including colorectal cancer (CRC), overexpress the MUC13 cell surface mucin, but the functional significance and mechanisms are unknown…”
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The magnitude rather than the rate of decline in fetal growth is a stronger risk factor for perinatal mortality in term infants
Published in American journal of obstetrics & gynecology MFM (01-02-2023)“…•Of note, ≥50th percentile fetal growth decline is associated with late fetal growth restrictions.•Of note, ≥50th percentile fetal growth decline is strongly…”
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100: EXOME SEQUENCING OF A FAMILY WITH A SEVERE COLITIS PHENOTYPE IDENTIFIES A RARE MISSENSE MUTATION IN A NOVEL IBD GENE
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2022)Get full text
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Facile synthesis of dendrimer like mesoporous silica nanoparticles to enhance targeted delivery of interleukin-22
Published in Biomaterials science (09-11-2021)“…Interleukin (IL)-22 is a multifunctional cytokine with a very short half-life that activates STAT3 and can elicit strong anti-inflammatory effects in the…”
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Factors Associated with Increased Risk of Early Severe Neonatal Morbidity in Late Preterm and Early Term Infants
Published in Journal of clinical medicine (23-03-2021)“…Although the risk of neonatal mortality is generally low for late preterm and early term infants, they are still significantly predisposed to severe neonatal…”
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Tu1898 Thiopurine Mediated Chemoprevention of Colitis-Associated Colorectal Dysplasia
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2016)Get full text
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Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages
Published in PLoS pathogens (01-01-2022)“…A hallmark of Listeria (L.) monocytogenes pathogenesis is bacterial escape from maturing entry vacuoles, which is required for rapid bacterial replication in…”
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Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages
Published in PLoS pathogens (01-01-2022)“…A hallmark of Listeria (L.) monocytogenes pathogenesis is bacterial escape from maturing entry vacuoles, which is required for rapid bacterial replication in…”
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Impact of co-administered drugs on drug monitoring of capecitabine in patients with advanced colorectal cancer
Published in Anticancer research (01-07-2014)“…Drug monitoring is a useful tool for obtaining detailed information about the disposition of a drug in an individual patient during chemotherapy. According to…”
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Development of potential selective and reversible pyrazoline based MAO-B inhibitors as MAO-B PET tracer precursors and reference substances for the early detection of Alzheimer’s disease
Published in Bioorganic & medicinal chemistry letters (15-09-2014)“…Since high MAO-B levels are present in early stages of AD, the MAO-B system can be designated as an appropriate and prospective tracer target of molecular…”
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