Search Results - "Schreiber, Stefan"
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An ecophysiological and developmental perspective on variation in vessel diameter
Published in Plant, cell and environment (01-06-2017)“…Variation in xylem vessel diameter is one of the most important parameters when evaluating plant water relations. This review provides a synthesis of the…”
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2
Development and validation of the Nancy histological index for UC
Published in Gut (01-01-2017)“…We developed a validated index for assessing histological disease activity in UC and established its responsiveness. Two hundred biopsies were scored. The…”
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Certolizumab pegol for the treatment of Crohn’s disease
Published in Therapeutic Advances in Gastroenterology (01-11-2011)“…In this article we provide a contemporary overview of available clinical data on certolizumab pegol, a pegylated anti-tumor necrosis factor (TNF) alpha agent…”
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4
Reduced microbiome alpha diversity in young patients with ADHD
Published in PloS one (12-07-2018)“…ADHD is a psychiatric disorder which is characterized by hyperactivity, impulsivity and attention problems. Due to recent findings of microbial involvement in…”
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Variation of xylem vessel diameters across a climate gradient: insight from a reciprocal transplant experiment with a widespread boreal tree
Published in Functional ecology (01-11-2015)“…Summary Xylem vessel diameters represent an important plant hydraulic trait to ensure sufficient water supply from the roots to the leaves. The ability to…”
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Tofacitinib as Induction and Maintenance Therapy for Ulcerative Colitis
Published in The New England journal of medicine (04-05-2017)“…In three phase 3 trials involving patients with ulcerative colitis, tofacitinib (an oral, small-molecule Janus kinase inhibitor) was more effective as…”
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Clinical remission in patients with moderate-to-severe Crohn's disease treated with filgotinib (the FITZROY study): results from a phase 2, double-blind, randomised, placebo-controlled trial
Published in The Lancet (British edition) (21-01-2017)“…Summary Background Filgotinib (GLPG0634, GS-6034) is a once-daily, orally administered, Janus kinase 1 (JAK1)-selective inhibitor. The FITZROY study examined…”
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Foliar water uptake in Pinus species depends on needle age and stomatal wax structures
Published in Annals of botany (08-03-2023)“…Foliar water uptake (FWU) has been documented in many species and is increasingly recognized as a non-trivial factor in plant-water relationships. However, it…”
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Correlation Between the Crohn's Disease Activity and Harvey–Bradshaw Indices in Assessing Crohn's Disease Severity
Published in Clinical gastroenterology and hepatology (01-04-2010)“…Background & Aims Clinical trials of Crohn's disease generally use the Crohn's Disease Activity Index to assess disease activity; these calculations are…”
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Induction therapy with the selective interleukin-23 inhibitor risankizumab in patients with moderate-to-severe Crohn's disease: a randomised, double-blind, placebo-controlled phase 2 study
Published in The Lancet (British edition) (29-04-2017)“…Summary Background The interleukin-23 pathway is implicated genetically and biologically in the pathogenesis of Crohn's disease. We aimed to assess the…”
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Systematic review with meta-analysis: real-world effectiveness and safety of vedolizumab in patients with inflammatory bowel disease
Published in Journal of gastroenterology (01-09-2018)“…Background Selective patient recruitment can produce discrepancies between clinical trial results and real-world effectiveness. Methods A systematic literature…”
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Growth and survival of native upland and wetland species in shallow capped thickened tailings: a meso-scale greenhouse study
Published in Canadian Journal of Soil Science (01-12-2023)“…This 3 year meso-scale greenhouse study used 55 gallon columns to evaluate the survival and growth of boreal upland and wetland communities on thickened…”
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A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis
Published in Nature genetics (01-12-2015)“…Felix Stickel and colleagues report the results of a genome-wide association study of alcohol-related cirrhosis. They confirm PNPLA3 as a susceptibility locus…”
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Twin Study Indicates Loss of Interaction Between Microbiota and Mucosa of Patients With Ulcerative Colitis
Published in Gastroenterology (New York, N.Y. 1943) (01-07-2011)“…Background & Aims Interactions between genetic and environmental factors are believed to be involved in onset and initiation of inflammatory bowel disease. We…”
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Geographical patterns of the standing and active human gut microbiome in health and IBD
Published in Gut (01-02-2016)“…A global increase of IBD has been reported, especially in countries that previously had low incidence rates. Also, the knowledge of the human gut microbiome is…”
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Association of FOXO3A variation with human longevity confirmed in German centenarians
Published in Proceedings of the National Academy of Sciences - PNAS (24-02-2009)“…The human forkhead box O3A gene (FOXO3A) encodes an evolutionarily conserved key regulator of the insulin-IGF1 signaling pathway that is known to influence…”
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Paneth cells as a site of origin for intestinal inflammation
Published in Nature (London) (14-11-2013)“…Variation in ATG16L1, a protein involved in autophagy, confers risk for Crohn’s disease, but mice with hypomorphic ATG16L1 activity do not develop spontaneous…”
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Case report: Induction and maintenance of steroid-free remission with vedolizumab in a case of steroid-dependent autoimmune pancreatitis
Published in Frontiers in immunology (19-06-2023)“…Autoimmune pancreatitis responds well to corticosteroids in most instances. Additional immunosuppression or low-dose maintenance steroids may be necessary upon…”
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DNA Methylation Analysis in Nonalcoholic Fatty Liver Disease Suggests Distinct Disease-Specific and Remodeling Signatures after Bariatric Surgery
Published in Cell metabolism (06-08-2013)“…Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder in industrialized countries. Liver samples from morbidly obese patients (n =…”
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Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues From Patients
Published in Gastroenterology (New York, N.Y. 1943) (01-09-2016)“…Background & Aims Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder in industrialized countries. Mouse models of NAFLD have…”
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