Search Results - "Schreiber, S. S"
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1
Superspreading and the effect of individual variation on disease emergence
Published in Nature (17-11-2005)“…Population-level analyses often use average quantities to describe heterogeneous systems, particularly when variation does not arise from identifiable groups…”
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2
Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome activity
Published in Oncogene (03-10-2013)“…Evidence accumulates that the transcription factor nuclear factor E2-related factor 2 (Nrf2) has an essential role in cancer development and chemoresistance,…”
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3
Vedolizumab induction therapy for inflammatory bowel disease in clinical practice – a nationwide consecutive German cohort study
Published in Alimentary pharmacology & therapeutics (01-05-2016)“…Summary Background Vedolizumab (VDZ) is a humanised monoclonal IgG1 antibody targeting α4β7 integrin. Aim To investigate the real‐world efficacy of vedolizumab…”
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4
Social information drives ecological outcomes among competing species
Published in Ecology (Durham) (01-11-2019)“…Through its behavior, an organism intentionally or unintentionally produces information. Use of this “social information” by surrounding conspecifics or…”
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5
Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target
Published in The American journal of gastroenterology (01-09-2015)“…The Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) program was initiated by the International Organization for the Study of Inflammatory…”
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6
Target-Oriented and Diversity-Oriented Organic Synthesis in Drug Discovery
Published in Science (American Association for the Advancement of Science) (17-03-2000)“…Modern drug discovery often involves screening small molecules for their ability to bind to a preselected protein target. Target-oriented syntheses of these…”
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7
Adalimumab for the treatment of fistulas in patients with Crohn's disease
Published in Gut (01-07-2009)“…To evaluate the efficacy of adalimumab in the healing of draining fistulas in patients with active Crohn's disease (CD). A phase III, multicentre, randomised,…”
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8
Printing Proteins as Microarrays for High-Throughput Function Determination
Published in Science (American Association for the Advancement of Science) (08-09-2000)“…Systematic efforts are currently under way to construct defined sets of cloned genes for high-throughput expression and purification of recombinant proteins…”
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9
Anti-TNF biosimilars in chronic inflammatory bowel disease. What can rheumatologists learn from it?
Published in Zeitschrift für Rheumatologie (01-10-2015)“…The expiry of the patent for tumor necrosis factor (TNF)-binding antibodies allowed the approval of biosimilars. Assessment and discussion of specific aspects…”
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10
Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau
Published in The Journal of neuroscience (05-11-2008)“…Memory loss is the signature feature of Alzheimer's disease, and therapies that prevent or delay its onset are urgently needed. Effective preventive strategies…”
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11
Nod2 is essential for temporal development of intestinal microbial communities
Published in Gut (01-10-2011)“…The mammalian commensal gut microbiota is highly diverse and displays an individual-specific composition determined by host genotype and environmental factors…”
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12
Recovery time of a plasma-wakefield accelerator
Published in Nature (London) (03-03-2022)“…The interaction of intense particle bunches with plasma can give rise to plasma wakes 1 , 2 capable of sustaining gigavolt-per-metre electric fields 3 , 4 ,…”
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13
Doppler and Duplex Sonography for the Diagnosis of the Irreversible Cessation of Brain Function ("Brain Death"): Current Guidelines in Germany and Neighboring Countries
Published in Ultraschall in der Medizin (01-12-2016)“…Extra- and transcranial sonography of brain-supplying arteries is accepted worldwide in brain death protocols as a valid "ancillary" method of proving brain…”
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14
Microgliosis and neuronal proteinopathy in brain persist beyond viral clearance in SARS-CoV-2 hamster model
Published in EBioMedicine (01-05-2022)“…Neurological symptoms such as cognitive decline and depression contribute substantially to post-COVID-19 syndrome, defined as lasting symptoms several weeks…”
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15
Do Disease Stories Need a Hero? Effects of Human Protagonists on a Narrative Visualization about Cerebral Small Vessel Disease
Published in Computer graphics forum (01-06-2023)“…Authors use various media formats to convey disease information to a broad audience, from articles and videos to interviews or documentaries. These media often…”
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16
Experimental demonstration of novel beam characterization using a polarizable X-band transverse deflection structure
Published in Scientific reports (11-02-2021)“…The PolariX TDS (Polarizable X-Band Transverse Deflection Structure) is an innovative TDS-design operating in the X-band frequency-range. The design gives full…”
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17
Antibiotic use among twelve Canadian First Nations communities: a retrospective chart review of skin and soft tissue infections
Published in BMC infectious diseases (10-02-2020)“…Previous publications indicated an emerging issue with community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA), particularly skin and soft…”
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Vedolizumab in the treatment of chronic, antibiotic‐dependent or refractory pouchitis
Published in Alimentary pharmacology & therapeutics (01-03-2018)“…Summary Background The most common complication after ileal pouch anal anastomosis in up to 50% of patients is an acute pouchitis. The majority of patients…”
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19
Trazodone and mirtazapine: A possible opioid involvement in their use (at low dose) for sleep?
Published in Medical hypotheses (01-03-2020)“…The efficacy of each antidepressant available has been found equal to that of amitriptyline in double-blind studies. However, a few of them are being…”
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20
Hope for the best or prepare for the worst? Towards a spatial cognitive bias test for mice
Published in PloS one (19-08-2014)“…Cognitive bias, the altered information processing resulting from the background emotional state of an individual, has been suggested as a promising new…”
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