Search Results - "Schreiber, Joerg"

Model‐guided combinatorial optimization of complex synthetic gene networks by Schreiber, Joerg, Arter, Meret, Lapique, Nicolas, Haefliger, Benjamin, Benenson, Yaakov

“…Constructing gene circuits that satisfy quantitative performance criteria has been a long‐standing challenge in synthetic biology. Here, we show a strategy for…”
Get full text

Transplantation of prokaryotic two-component signaling pathways into mammalian cells by Hansen, Jonathan, Mailand, Erik, Swaminathan, Krishna Kumar, Schreiber, Joerg, Angelici, Bartolomeo, Benenson, Yaakov

“…Signaling pathway engineering is a promising route toward synthetic biological circuits. Histidine–aspartate phosphorelays are thought to have evolved in…”
Get full text

A laser-driven nanosecond proton source for radiobiological studies by Bin, Jianhui, Allinger, Klaus, Assmann, Walter, Dollinger, Guenther, Drexler, Guido A, Friedl, Anna A, Habs, Dieter, Hilz, Peter, Hoerlein, Rainer, Humble, Nicole

“…Ion beams are relevant for radiobiological studies and for tumor therapy. In contrast to conventional accelerators, laser-driven ion acceleration offers a…”
Get full text

Coordinated Binding of NF-κB Family Members in the Response of Human Cells to Lipopolysaccharide by Schreiber, Joerg, Jenner, Richard G., Murray, Heather L., Gerber, Georg K., Gifford, David K., Young, Richard A.

“…The NF-κB family of transcription factors plays a critical role in numerous cellular processes, particularly the immune response. Our understanding of how the…”
Get full text

Rescue bedside laparotomy in the intensive care unit in patients too unstable for transport to the operating room by Schreiber, Joerg, Nierhaus, Axel, Vettorazzi, Eik, Braune, Stephan A, Frings, Daniel P, Vashist, Yogesh, Izbicki, Jakob R, Kluge, Stefan

“…The prognoses of critically ill patients with a requirement for emergency laparotomy and severe respiratory and/or hemodynamic instability precluding transport…”
Get full text

An AAV gene therapy computes over multiple cellular inputs to enable precise targeting of multifocal hepatocellular carcinoma in mice by Angelici, Bartolomeo, Shen, Linling, Schreiber, Joerg, Abraham, Anthony, Benenson, Yaakov

“…Clinical translation of multi-input biomolecular computing systems holds potential to lead to disease-tailored, data-driven rational design of next-generation…”
Get more information

O09 Long-term safety of ustekinumab in paediatric patients with moderate-to-severe plaque psoriasis: results from an ongoing observational study by Mahé, Emmanuel, Geldhof, Anja, Movshovich, Evgenia, Schreiber, Joerg, Malynn, Sandra, Efficace, Michela, Seyger, Marieke M B

“…Abstract The European Medicines Agency approved ustekinumab for psoriasis treatment in adolescents (12–17 years) in 2015 (CADMUS trial), and children (6–11…”
Get full text

On the robustness of multilateration of ionoacoustic signals for localization of the Bragg peak at pre-clinical proton beam energies in water by Kalunga, Ronaldo, Wieser, Hans-Peter, Dash, Pratik, Würl, Matthias, Riboldi, Marco, Schreiber, Jörg, Assmann, Walter, Parodi, Katia, Lascaud, Julie

“…The energy deposited in a medium by a pulsed proton beam results in the emission of thermoacoustic waves, also called ionoacoustics (IA). The proton beam…”
Get more information

A feasibility study of zebrafish embryo irradiation with laser-accelerated protons by Rösch, Thomas F, Szabó, Zoltán, Haffa, Daniel, Bin, Jianhui, Brunner, Szilvia, Englbrecht, Franz S, Friedl, Anna A, Gao, Ying, Hartmann, Jens, Hilz, Peter, Kreuzer, Christian, Lindner, Florian H, Ostermayr, Tobias M, Polanek, Róbert, Speicher, Martin, Szabó, Emília R, Taray, Derya, Tőkés, Tünde, Würl, Matthias, Parodi, Katia, Hideghéty, Katalin, Schreiber, Jörg

“…The development from single shot basic laser plasma interaction research toward experiments in which repetition rated laser-driven ion sources can be applied…”
Get more information

Analyses of sphingosine‐1‐phosphate in the context of transfusion: how much is in stored blood products and in patient blood? by Poppe, Annika, Moritz, Eileen, Geffken, Maria, Schreiber, Joerg, Greiwe, Gillis, Amschler, Katharina, Wruck, Marie‐Louise, Schwedhelm, Edzard, Daum, Günter, Kluge, Stefan, Peine, Sven, Winkler, Martin Sebastian

“…BACKGROUND Sphingosine‐1‐phosphate (S1P) is a bloodborne lipid that regulates vascular tone and endothelial permeability. S1P concentrations are reduced in…”
Get full text

Preoperative autologous blood donation versus intraoperative blood salvage: intraindividual analyses and modeling of efficacy in 1103 patients by Singbartl, Guenter, Schreiber, Joerg, Singbartl, Kai

“…BACKGROUND: Preoperative autologous blood donation (PABD) and intraoperative blood salvage (IBS) represent established blood conservation measures. However,…”
Get full text

Towards a novel small animal proton irradiation platform: the SIRMIO project by Parodi, Katia, Assmann, Walter, Belka, Claus, Bortfeldt, Jonathan, Clevert, Dirk-André, Dedes, George, Kalunga, Ronaldo, Kundel, Sonja, Kurichiyanil, Neeraj, Lämmer, Paulina, Lascaud, Julie, Lauber, Kirsten, Lovatti, Giulio, Meyer, Sebastian, Nitta, Munetaka, Pinto, Marco, Safari, Mohammad J, Schnürle, Katrin, Schreiber, Jörg, Thirolf, Peter G, Wieser, Hans-Peter, Würl, Matthias

“…Precision small animal radiotherapy research is a young emerging field aiming to provide new experimental insights into tumor and normal tissue models in…”
Get more information

Temporally Resolved Intensity Contouring (TRIC) for characterization of the absolute spatio-temporal intensity distribution of a relativistic, femtosecond laser pulse by Haffa, Daniel, Bin, Jianhui, Speicher, Martin, Allinger, Klaus, Hartmann, Jens, Kreuzer, Christian, Ridente, Enrico, Ostermayr, Tobias M., Schreiber, Jörg

“…Today’s high-power laser systems are capable of reaching photon intensities up to 10 22 W cm −2 , generating plasmas when interacting with material. The high…”
Get full text

MiR-133b targets antiapoptotic genes and enhances death receptor-induced apoptosis by Patron, Juan P, Fendler, Annika, Bild, Matthias, Jung, Ulrike, Müller, Henrik, Arntzen, Magnus Ø, Piso, Chloe, Stephan, Carsten, Thiede, Bernd, Mollenkopf, Hans-Joachim, Jung, Klaus, Kaufmann, Stefan H E, Schreiber, Jörg

“…Despite the importance of microRNAs (miRs) for regulation of the delicate balance between cell proliferation and death, evidence for their specific involvement…”
Get full text

Genome-wide profiling of the activity-dependent hippocampal transcriptome by Hermey, Guido, Mahlke, Claudia, Gutzmann, Jakob J, Schreiber, Jörg, Blüthgen, Nils, Kuhl, Dietmar

“…Activity-dependent gene expression is central for sculpting neuronal connectivity in the brain. Despite the importance for synaptic plasticity, a comprehensive…”
Get full text

Single-shot laser-induced damage threshold of free-standing nanometer-thin diamond-like carbon foils by Wang, Dahui, Ma, Wenjun, Bin, Jianhui, Alinger, Klaus, Shou, Yinren, Wang, Pengjie, Liu, Jianbo, Zhu, Jungao, Cao, Zhengxuan, Mei, Zhusong, Wang, Hongyong, Lu, Haiyang, Lin, Chen, Zhao, Yanying, Schreiber, Joerg, Yan, Xueqing

“…Single-shot laser-induced damage threshold (LIDT) of free-standing nanometer-thin diamond-like carbon (DLC) foils was measured in vacuum environment for pulse…”
Get full text

I-BEAT: Ultrasonic method for online measurement of the energy distribution of a single ion bunch by Haffa, Daniel, Yang, Rong, Bin, Jianhui, Lehrack, Sebastian, Brack, Florian-Emanuel, Ding, Hao, Englbrecht, Franz S., Gao, Ying, Gebhard, Johannes, Gilljohann, Max, Götzfried, Johannes, Hartmann, Jens, Herr, Sebastian, Hilz, Peter, Kraft, Stephan D., Kreuzer, Christian, Kroll, Florian, Lindner, Florian H., Metzkes-Ng, Josefine, Ostermayr, Tobias M., Ridente, Enrico, Rösch, Thomas F., Schilling, Gregor, Schlenvoigt, Hans-Peter, Speicher, Martin, Taray, Derya, Würl, Matthias, Zeil, Karl, Schramm, Ulrich, Karsch, Stefan, Parodi, Katia, Bolton, Paul R., Assmann, Walter, Schreiber, Jörg

“…The shape of a wave carries all information about the spatial and temporal structure of its source, given that the medium and its properties are known. Most…”
Get full text

Abstract 5799: Novel nanoparticle technology targets the delivery of polyIC to EGFR overexpressing cancers and induces a multimodal anti-tumor response by Broka, Derrick, De Feyter, Caroline, Klein, Shoshana, Saxena, Meera, Schreiber, Joerg, Shir, Alexei, Skowicki, Michal, Benenson, Yaakov, Levitzki, Alexander, Palivan, Cornelia G., Pombo-Villar, Esteban, Schade, Babette, Zigler, Maya

“…Abstract Aberrant activation of epidermal growth factor receptor (EGFR) signaling pathways is associated with tumor growth and progression. EGFR overexpression…”
Get full text

Mutation in the transcriptional regulator PhoP contributes to avirulence of Mycobacterium tuberculosis H37Ra strain by Lee, Jong Seok, Krause, Roland, Schreiber, Jörg, Mollenkopf, Hans-Joachim, Kowall, Jane, Stein, Robert, Jeon, Bo-Young, Kwak, Jeong-Yeon, Song, Min-Kyong, Patron, Juan Pablo, Jorg, Sabine, Roh, Kyoungmin, Cho, Sang-Nae, Kaufmann, Stefan H E

“…Attenuated strains of mycobacteria can be exploited to determine genes essential for their pathogenesis and persistence. To this goal, we sequenced the genome…”
Get full text

A Workflow for In Vivo Evaluation of Candidate Inputs and Outputs for Cell Classifier Gene Circuits by Dastor, Margaux, Schreiber, Joerg, Prochazka, Laura, Angelici, Bartolomeo, Kleinert, Jonathan, Klebba, Ina, Doshi, Jiten, Shen, Linling, Benenson, Yaakov

“…Cell classifier gene circuits that integrate multiple molecular inputs to restrict the expression of therapeutic outputs to cancer cells have the potential to…”
Get full text