Search Results - "Schreiber, Anne"
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Substrate recognition in selective autophagy and the ubiquitin-proteasome system
Published in Biochimica et biophysica acta (01-01-2014)“…Dynamic protein turnover through regulated protein synthesis and degradation ensures cellular growth, proliferation, differentiation and adaptation. Eukaryotic…”
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Diabetic neuropathic pain: Physiopathology and treatment
Published in World journal of diabetes (15-04-2015)“…Diabetic neuropathy is a common complication of bothtype 1 and type 2 diabetes, which affects over 90% ofthe diabetic patients. Although pain is one of the…”
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Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery
Published in Nature cell biology (01-11-2016)“…The endoplasmic reticulum (ER) is a site of protein biogenesis in eukaryotic cells. Perturbing ER homeostasis activates stress programs collectively called the…”
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Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase
Published in Nature structural & molecular biology (01-01-2022)“…Loading of the eukaryotic replicative helicase onto replication origins involves two MCM hexamers forming a double hexamer (DH) around duplex DNA. During S…”
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Autophagosome membrane expansion is mediated by the N-terminus and cis -membrane association of human ATG8s
Published in eLife (08-06-2023)“…Autophagy is an essential catabolic pathway which sequesters and engulfs cytosolic substrates via autophagosomes, unique double-membraned structures. ATG8…”
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Depression Associated with Diabetes: From Pathophysiology to Treatment
Published in Current diabetes reviews (01-09-2016)“…Diabetes is a chronic and progressive syndrome commonly associated with several neuropsychiatric comorbities, of which depression is the most studied. The…”
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Structural basis for the subunit assembly of the anaphase-promoting complex
Published in Nature (London) (10-02-2011)“…The anaphase-promoting complex or cyclosome (APC/C) is an unusually large E3 ubiquitin ligase responsible for regulating defined cell cycle transitions…”
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Chlorpyrifos induces anxiety-like behavior in offspring rats exposed during pregnancy
Published in Neuroscience letters (22-02-2017)“…•Chlorpyrifos induces anxiogenic-like effects in male offspring.•Chlorpyrifos did not induces depressive-like effects in male offspring.•Fetal neurodevelopment…”
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Structural Basis for a Reciprocal Regulation between SCF and CSN
Published in Cell reports (Cambridge) (27-09-2012)“…Skp1-Cul1-Fbox (SCF) E3 ligases are activated by ligation to the ubiquitin-like protein Nedd8, which is reversed by the deneddylating Cop9 signalosome (CSN)…”
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Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle
Published in eLife (31-03-2016)“…The COP9-Signalosome (CSN) regulates cullin-RING ubiquitin ligase (CRL) activity and assembly by cleaving Nedd8 from cullins. Free CSN is autoinhibited, and it…”
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Effect of omega-3 polyunsaturated fatty acid treatment over mechanical allodynia and depressive-like behavior associated with experimental diabetes
Published in Behavioural brain research (01-02-2016)“…•Fish oil prevents the mechanical allodynia in diabetic rats.•Fish oil exerts an antidepressant-like effect in diabetic rats.•Fish oil restores the BDNF levels…”
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A non-canonical role: The Hippo pathway regulator MAP4K2 controls autophagy and cell survival upon energy stress
Published in Molecular cell (07-09-2023)Get full text
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13
Peripheral antinociceptive effect of anandamide and drugs that affect the endocannabinoid system on the formalin test in normal and streptozotocin-diabetic rats
Published in Neuropharmacology (01-12-2012)“…Diabetes is often associated with painful neuropathy. The current treatments are symptomatic and ineffective. Cannabinoids have been proposed as promising…”
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Comparative study of cold hyperalgesia and mechanical allodynia in two animal models of neuropathic pain: different etiologies and distinct pathophysiological mechanisms
Published in Brazilian Journal of Pharmaceutical Sciences (01-01-2022)“…Abstract Neuropathic pain (NP) affects more than 8% of the global population. The proposed action of the transient receptor potential ankyrin 1 (TRPA1) as a…”
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Meet the authors: Anne Schreiber and Ben C. Collins
Published in Molecular cell (16-12-2021)“…Here, we talk to Anne Schreiber and Ben C. Collins about their collaboration, which started during their postdoc time in Zurich and endured as they both…”
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Erratum: Corrigendum: Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery
Published in Nature cell biology (01-01-2017)Get full text
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Organisation durch Kommunikation Medien des Managements in den USA Anfang des 20. Jahrhunderts
Published in Zeitschrift für Medienwissenschaft (01-03-2018)Get full text
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Multilayered regulation of autophagy by the Atg1 kinase orchestrates spatial and temporal control of autophagosome formation
Published in Molecular cell (16-12-2021)“…Autophagy is a conserved intracellular degradation pathway exerting various cytoprotective and homeostatic functions by using de novo double-membrane vesicle…”
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Methamphetamine withdrawal and the restoration of cognitive functions – a study over a course of 6 months abstinence
Published in Psychiatry research (01-11-2019)“…•Long-term MA intake was identified as indicator of poorer cognitive performance.•declines in general neurophysiological functioning with ongoing years of…”
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Deep Molecular Response Is Reached by the Majority of Patients Treated With Imatinib, Predicts Survival, and Is Achieved More Quickly by Optimized High-Dose Imatinib: Results From the Randomized CML-Study IV
Published in Journal of clinical oncology (10-02-2014)“…Deep molecular response (MR(4.5)) defines a subgroup of patients with chronic myeloid leukemia (CML) who may stay in unmaintained remission after treatment…”
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