Search Results - "Schreck, Ilona"

In vivo multiple metabolic pathways for a novel G protein-coupled receptor 119 agonist DS-8500a in rats: involvement of the 1,2,4-oxadiazole ring-opening reductive reaction in livers under anaerobic conditions by Makino, Chie, Watanabe, Akiko, Deguchi, Tsuneo, Shiozawa, Hideyuki, Schreck, Ilona, Rozehnal, Veronika, Ishizuka, Tomoko, Watanabe, Nobuaki, Ando, Osamu, Murayama, Norie, Yamazaki, Hiroshi

“…A 1,2,4-oxadiazole ring-containing compound DS-8500a was developed as a novel G protein-coupled receptor 119 agonist. In vivo metabolic fates of [ 14…”
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Differential p38-dependent signalling in response to cellular stress and mitogenic stimulation in fibroblasts by Faust, Dagmar, Schmitt, Christina, Oesch, Franz, Oesch-Bartlomowicz, Barbara, Schreck, Ilona, Weiss, Carsten, Dietrich, Cornelia

“…p38 MAP kinase is known to be activated by cellular stress finally leading to cell cycle arrest or apoptosis. Furthermore, a tumour suppressor role of p38 MAPK…”
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The Alternaria mycotoxins alternariol and alternariol methyl ether induce cytochrome P450 1A1 and apoptosis in murine hepatoma cells dependent on the aryl hydrocarbon receptor by Schreck, Ilona, Deigendesch, Ute, Burkhardt, Britta, Marko, Doris, Weiss, Carsten

“…The Alternaria mycotoxins alternariol (AOH) and alternariol methyl ether (AME) are potential carcinogens. As planar compounds, AOH and AME are preferentially…”
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Role and interaction of p53, BAX and the stress-activated protein kinases p38 and JNK in benzo(a)pyrene-diolepoxide induced apoptosis in human colon carcinoma cells by Donauer, Julia, Schreck, Ilona, Liebel, Urban, Weiss, Carsten

“…Polycyclic aromatic hydrocarbons are ubiquitous environmental pollutants formed during incomplete combustion of organic material. For example benzo[a]pyrene…”
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Enhancer cooperativity as a novel mechanism underlying the transcriptional regulation of E-cadherin during mesenchymal to epithelial transition by Alotaibi, Hani, Basilicata, M. Felicia, Shehwana, Huma, Kosowan, Tyler, Schreck, Ilona, Braeutigam, Christien, Konu, Ozlen, Brabletz, Thomas, Stemmler, Marc P.

“…Epithelial–mesenchymal transition (EMT) and mesenchymal–epithelial transition (MET) highlight crucial steps during embryogenesis and tumorigenesis. Induction…”
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Chk1 Targeting Reactivates PP2A Tumor Suppressor Activity in Cancer Cells by KHANNA, Anchit, KAUKO, Otto, POKHAREL, Yuba R, PIMANDA, John, RUSSEL, Mike R, HAGLUND, Caj, COLE, Kristina A, KLEFSTRÖM, Juha, AITTOKALLIO, Tero, WEISS, Carsten, RISTIMÄKI, Ari, VISAKORPI, Tapio, BÖCKELMAN, Camilla, WESTERMARCK, Jukka, LAINE, Anni, SCHRECK, Ilona, PARTANEN, Johanna I, SZWAJDA, Agnieszka, BORMANN, Stefanie, BILGEN, Turker, HELENIUS, Merja

“…Checkpoint kinase Chk1 is constitutively active in many cancer cell types and new generation Chk1 inhibitors show marked antitumor activity as single agents…”
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c-Jun localizes to the nucleus independent of its phosphorylation by and interaction with JNK and vice versa promotes nuclear accumulation of JNK by Schreck, Ilona, Al-Rawi, Marco, Mingot, José-Manuel, Scholl, Christine, Diefenbacher, Markus Elmar, O’Donnell, Paul, Bohmann, Dirk, Weiss, Carsten

“…► HSP70, Ku70 and 80 as well as importin 8 are novel interactors of c-Jun. ► Nuclear accumulation of c-Jun does not require its functions as a transcription…”
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Abstract 4194: Constitutive DNA-damage signaling promotes cancer cell proliferation through Chk1-CIP2A pathway independent of ATM-ATR by Khanna, Anchit, Böckelman, Camilla, Schreck, Ilona, Weiss, Carsten, Visakorpi, Tapio, Ristimäki, Ari, Westermarck, Jukka

“…Abstract DNA damage is a hallmark of malignantly transformed cells. Accordingly, overexpression of the DNA damage activated kinases has been observed in…”
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Influence of aryl hydrocarbon- (Ah) receptor and genotoxins on DNA repair gene expression and cell survival of mouse hepatoma cells by Schreck, Ilona, Chudziak, Doreen, Schneider, Sandra, Seidel, Albrecht, Platt, Karl L, Oesch, Franz, Weiss, Carsten

“…Abstract The aryl hydrocarbon receptor (AhR) mediates toxicity of a variety of environmental pollutants such as polycyclic aromatic hydrocarbons (PAHs) and…”
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