Search Results - "Schrank, Sean"

Human-Induced Neurons from Presenilin 1 Mutant Patients Model Aspects of Alzheimer's Disease Pathology by Schrank, Sean, McDaid, John, Briggs, Clark A, Mustaly-Kalimi, Sarah, Brinks, Deanna, Houcek, Aiden, Singer, Oded, Bottero, Virginie, Marr, Robert A, Stutzmann, Grace E

“…Traditional approaches to studying Alzheimer's disease (AD) using mouse models and cell lines have advanced our understanding of AD pathogenesis. However, with…”
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Viral tools for mapping and modulating neural networks after spinal cord injury by Schrank, Sean, Satkunendrarajah, Kajana

“…Repairing the damaged neural networks in traumatic spinal cord injury presents a difficult challenge for neuroscientists. While significant progress has been…”
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Calcium-Handling Defects and Neurodegenerative Disease by Schrank, Sean, Barrington, Nikki, Stutzmann, Grace E

“…Calcium signaling is critical to neuronal function and regulates highly diverse processes such as gene transcription, energy production, protein handling, and…”
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Neuropathological signaling in AD human induced neurons by Stutzmann, Grace E, Marr, Robert, Mustaly, Sarah H, Schrank, Sean

“…Background Neurons and other CNS‐based cells derived from human AD patients are increasingly used for investigating cellular and molecular mechanisms of AD,…”
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Liposaccharide-induced sustained mild inflammation fragments social behavior and alters basolateral amygdala activity by Loh, Maxine K., Stickling, Courtney, Schrank, Sean, Hanshaw, Madison, Ritger, Alexandra C., Dilosa, Naijila, Finlay, Joshua, Ferrara, Nicole C., Rosenkranz, J. Amiel

“…Rationale Conditions with sustained low-grade inflammation have high comorbidity with depression and anxiety and are associated with social withdrawal. The…”
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Lysosome‐autophagosome defects mediate proteinopathy in early stages of Alzheimer’s disease by Mustaly, Sarah H, Beaman, Kenneth D, Gilman‐Sachs, Alice, Schrank, Sean, Marr, Robert, Stutzmann, Grace E

“…Background Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by abnormal protein aggregation and synaptic deficits. To regulate normal…”
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Lysosome‐autophagosome defects mediate proteinopathy in early stages of Alzheimer’s disease: Developing topics by Mustaly, Sarah H, Beaman, Kenneth D, Gilman‐Sachs, Alice, Schrank, Sean, Marr, Robert, Stutzmann, Grace E

“…Abstract Background Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by abnormal protein aggregation and synaptic deficits. To regulate…”
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Binge ethanol consumption can be attenuated by systemic administration of minocycline and is associated with enhanced neuroinflammation in the central amygdala by Schrank, Sean, Sevigny, Joshua P., Yunus, N. Ika, Vetter, Katherine R., Aguilar, Oscar D., Ily, Vivek, Valchinova, Mikaela, Keinath, Alexandra T., Sparta, Dennis R.

“…Alcohol use disorder (AUD) has a complicated pathophysiology. Binge ethanol intoxication may produce long-lasting changes throughout extended amygdala…”
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HUMAN INDUCED NEURONS MODEL HALLMARKS OF ALZHEIMER’S DISEASE by Schrank, Sean, Briggs, Clark, McDaid, John, Maigler, Kathleen, Marr, Robert, Stutzmann, Grace E.

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P3‐074: HUMAN INDUCED NEURONS MODEL HALLMARKS OF ALZHEIMER'S DISEASE by Schrank, Sean, Briggs, Clark, McDaid, John, Maigler, Kathleen, Marr, Robert, Stutzmann, Grace E.

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Advancements in Neurodegenerative Disease Models: Human Induced Neurons Can Be Used to Elucidate Complex Disease Pathologies by Schrank, Sean Crispin

“…Advancements in stem cell technology and progress in genetic manipulation techniques involving viral vectors have revolutionized our ability to study…”
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P1‐216: LYSOSOME‐AUTOPHAGOSOME DEFECTS MEDIATE PROTEINOPATHY AND SYNAPTIC PATHOPHYSIOLOGY IN EARLY STAGES OF ALZHEIMER'S DISEASE by Mustaly, Sarah H., Garstka, Megan, Kapecki, Nicolas, Beaman, Kenneth D., Gilman-Sachs, Alice, McDaid, John, Schrank, Sean, Marr, Robert, Stutzmann, Grace E.

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LYSOSOME-AUTOPHAGOSOME DEFECTS MEDIATE PROTEINOPATHY AND SYNAPTIC PATHOPHYSIOLOGY IN EARLY STAGES OF ALZHEIMER’S DISEASE by Mustaly, Sarah H., Garstka, Megan, Kapecki, Nicolas, Beaman, Kenneth D., Gilman-Sachs, Alice, McDaid, John, Schrank, Sean, Marr, Robert, Stutzmann, Grace E.

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