Search Results - "Schramm, A"
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Microalgae–bacteria symbiosis in microalgal growth and biofuel production: a review
Published in Journal of applied microbiology (01-02-2019)“…Summary Photosynthetic microalgae can capture solar energy and convert it to bioenergy and biochemical products. In nature or industrial processes, microalgae…”
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Computer-assisted oral and maxillofacial surgery — what has become clinical routine after 20 years
Published in International journal of oral and maxillofacial surgery (01-03-2017)Get full text
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Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B cell Responses to Influenza Hemagglutinin
Published in Immunity (Cambridge, Mass.) (20-08-2019)“…Vaccine-induced memory B cell responses to evolving viruses like influenza A involve activation of pre-existing immunity and generation of new responses. To…”
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Beyond Hot Spots: Biases in Antibody Somatic Hypermutation and Implications for Vaccine Design
Published in Frontiers in immunology (14-08-2018)“…The evolution of antibodies in an individual during an immune response by somatic hypermutation (SHM) is essential for the ability of the immune system to…”
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The Membrane- and Soluble-Protein Helix-Helix Interactome: Similar Geometry via Different Interactions
Published in Structure (London) (03-03-2015)“…α Helices are a basic unit of protein secondary structure and therefore the interaction between helices is crucial to understanding tertiary and higher-order…”
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Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation
Published in Leukemia (01-09-2012)“…Lysine (K)-specific demethylase 1A (LSD1/KDM1A) has been identified as a potential therapeutic target in solid cancers and more recently in acute myeloid…”
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Determinants of Microscale pH in In Situ–Grown Dental Biofilms
Published in Journal of dental research (01-11-2023)“…Dental biofilm pH is the most important determinant of virulence for the development of caries lesions. Confocal microscopy–based pH ratiometry allows…”
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Comprehensive characterization of RB1 mutant and MYCN amplified retinoblastoma cell lines
Published in Experimental cell research (15-02-2019)“…In retinoblastoma research tumor-derived cell lines remain an important model to investigate tumorigenesis and new therapy options, due to limited tumor…”
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Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages
Published in mBio (26-02-2019)“…Influenza vaccines targeting the highly conserved stem of the hemagglutinin (HA) surface glycoprotein have the potential to protect against pandemic and…”
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Gene-Specific Substitution Profiles Describe the Types and Frequencies of Amino Acid Changes during Antibody Somatic Hypermutation
Published in Frontiers in immunology (10-05-2017)“…Somatic hypermutation (SHM) plays a critical role in the maturation of antibodies, optimizing recognition initiated by recombination of V(D)J genes. Previous…”
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MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cells
Published in Oncogene (21-02-2013)“…Neuroblastoma is an embryonal tumor with a heterogeneous clinical course. The tumor is presumed to be derived from the neural crest, but the cells of origin…”
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A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies
Published in Oncogene (01-06-2015)“…Neuroblastoma, a childhood cancer that originates from neural crest-derived cells, is the most common deadly solid tumor of infancy. Amplification of the MYCN…”
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SONAR: A High-Throughput Pipeline for Inferring Antibody Ontogenies from Longitudinal Sequencing of B Cell Transcripts
Published in Frontiers in immunology (21-09-2016)“…The rapid advance of massively parallel or next-generation sequencing technologies has made possible the characterization of B cell receptor repertoires in…”
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HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies
Published in Cell reports (Cambridge) (28-04-2020)“…Structural and functional studies of HIV envelope glycoprotein (Env) as a transmembrane protein have long been complicated by challenges associated with…”
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AIRR Community Standardized Representations for Annotated Immune Repertoires
Published in Frontiers in immunology (28-09-2018)“…Increased interest in the immune system's involvement in pathophysiological phenomena coupled with decreased DNA sequencing costs have led to an explosion of…”
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Interaction dynamics between innate and adaptive immune cells responding to SARS-CoV-2 vaccination in non-human primates
Published in Nature communications (02-12-2023)“…As SARS-CoV-2 variants continue evolving, testing updated vaccines in non-human primates remains important for guiding human clinical practice. To date, such…”
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Correction: Bone morphogenetic protein-7 is a MYC target with prosurvival functions in childhood medulloblastoma
Published in Oncogene (01-01-2023)Get full text
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Effectiveness of botulinum neurotoxin type A injections in naïve and previously-treated patients suffering from Torti- or Laterocollis or -caput: Results from a German-Austrian open-label prospective post-marketing surveillance study
Published in Journal of the neurological sciences (15-04-2019)“…AbobotulinumtoxinA (aboBoNT-A; Dysport®) is an effective treatment for cervical dystonia (CD) with a well-established safety profile. In this prospective,…”
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Modulation of neuroblastoma disease pathogenesis by an extensive network of epigenetically regulated microRNAs
Published in Oncogene (13-06-2013)“…MicroRNAs (miRNAs) contribute to the pathogenesis of many forms of cancer, including the pediatric cancer neuroblastoma, but the underlying mechanisms leading…”
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