Search Results - "Schrøder, Jacob M"

Assembly of primary cilia by Pedersen, Lotte B., Veland, Iben R., Schrøder, Jacob M., Christensen, Søren T.

“…Primary cilia are microtubule‐based, hair‐like sensory organelles present on the surface of most growth‐arrested cells in our body. Recent research has…”
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CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-β/BMP Signaling at the Primary Cilium by Mönnich, Maren, Borgeskov, Louise, Breslin, Loretta, Jakobsen, Lis, Rogowski, Michaela, Doganli, Canan, Schrøder, Jacob M., Mogensen, Johanne B., Blinkenkjær, Louise, Harder, Lea M., Lundberg, Emma, Geimer, Stefan, Christensen, Søren T., Andersen, Jens S., Larsen, Lars A., Pedersen, Lotte B.

“…The centrosome is the main microtubule-organizing center in animal cells and comprises a mother and daughter centriole surrounded by pericentriolar material…”
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Renal-retinal ciliopathy gene Sdccag8 regulates DNA damage response signaling by Airik, Rannar, Slaats, Gisela G, Guo, Zhi, Weiss, Anna-Carina, Khan, Naheed, Ghosh, Amiya, Hurd, Toby W, Bekker-Jensen, Simon, Schrøder, Jacob M, Elledge, Steve J, Andersen, Jens S, Kispert, Andreas, Castelli, Maddalena, Boletta, Alessandra, Giles, Rachel H, Hildebrandt, Friedhelm

“…Nephronophthisis-related ciliopathies (NPHP-RCs) are developmental and degenerative kidney diseases that are frequently associated with extrarenal pathologies…”
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EB1 and EB3 promote cilia biogenesis by several centrosome-related mechanisms by Schrøder, Jacob M, Larsen, Jesper, Komarova, Yulia, Akhmanova, Anna, Thorsteinsson, Rikke I, Grigoriev, Ilya, Manguso, Robert, Christensen, Søren T, Pedersen, Stine F, Geimer, Stefan, Pedersen, Lotte B

“…The microtubule (MT) plus-end-tracking protein EB1 is required for assembly of primary cilia in mouse fibroblasts, but the mechanisms involved and the roles of…”
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SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is Required for Hedgehog Signaling by Airik, Rannar, Schueler, Markus, Airik, Merlin, Cho, Jang, Ulanowicz, Kelsey A, Porath, Jonathan D, Hurd, Toby W, Bekker-Jensen, Simon, Schrøder, Jacob M, Andersen, Jens S, Hildebrandt, Friedhelm

“…Recessive mutations in the SDCCAG8 gene cause a nephronophthisis-related ciliopathy with Bardet-Biedl syndrome-like features in humans. Our previous…”
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EB1 Is Required for Primary Cilia Assembly in Fibroblasts by Schrøder, Jacob M., Schneider, Linda, Christensen, Søren T., Pedersen, Lotte B.

“…EB1 is a small microtubule (MT)-binding protein that associates preferentially with MT plus ends and plays a role in regulating MT dynamics. EB1 also targets…”
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The ciliary cytoskeleton by Pedersen, Lotte B, Schrøder, Jacob M, Satir, Peter, Christensen, Søren T

“…Cilia and flagella are surface-exposed, finger-like organelles whose core consists of a microtubule (MT)-based axoneme that grows from a modified centriole,…”
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EB1 and EB3 promote cilia biogenesis by several centrosome-related mechanisms by Schrøder, Jacob M., Larsen, Jesper, Komarova, Yulia, Akhmanova, Anna, Thorsteinsson, Rikke I., Grigoriev, Ilya, Manguso, Robert, Christensen, Søren T., Pedersen, Stine F., Geimer, Stefan, Pedersen, Lotte B.

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Durability of porcine and pericardial prostheses in tricuspid valve replacementCentral MessagePerspective by Brittany A. Zwischenberger, MD, MHSc, Carmelo Milano, MD, John Haney, MD, Jeffrey G. Gaca, MD, Jacob Schroder, MD, Keith Carr, BS, Donald D. Glower, MD

“…Objective: Biologic valves dominate tricuspid valve replacement, yet data on different valve types are lacking. We compare the survival and durability of…”
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The Risk of Acute Kidney Injury With Co-Occurrence of Anemia and Hypotension During Cardiopulmonary Bypass Relative to Anemia Alone by Sickeler, Robert, BS, Phillips-Bute, Barbara, PhD, Kertai, Miklos D., MD, PhD, Schroder, Jacob, MD, Mathew, Joseph P., MD, Swaminathan, Madhav, MD, Stafford-Smith, Mark, MD

“…Background Postoperative acute kidney injury (AKI) is a common serious consequence of cardiac surgery. One recent study found higher AKI rates when anemia and…”
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Value of nutritional indices in predicting survival free from pump replacement and driveline infections in centrifugal left ventricular assist devicesCentral MessagePerspective by Fabian Jimenez Contreras, MD, Bret L. Pinsker, MD, Jason N. Katz, MD, MHS, Stuart D. Russell, MD, Jacob Schroder, MD, Benjamin Bryner, MD, Alexander H. Gunn, MD, Krunal Amin, MD, Carmelo Milano, MD

“…Objective: There is a paucity of data assessing the impact of nutritional status on outcomes in patients supported with the HeartMate 3 (HM3) left ventricular…”
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Simultaneous transcarotid artery revascularization with flow reversal and coronary artery bypass grafting: A novel hybrid technique by Williams, Zachary F., Olivere, Lindsey A., Schroder, Jacob, Cox, Mitchell W., Long, Chandler A., Southerland, Kevin W.

“…Optimal management of concomitant coronary artery disease and carotid artery stenosis remains unknown. Current treatment strategies for patients with…”
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Noninvasive electrocardiographic mapping of ventricular tachycardia in a patient with a left ventricular assist device by Rehorn, Michael R., Koontz, Jason, Barnett, Adam S., Black-Maier, Eric, Piccini, Jonathan P., Loring, Zak, Schroder, Jacob, Sun, Albert Y.

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Regional variation in donation after circulatory death heart allograft utilizationCentral MessagePerspective by Oliver K. Jawitz, MD, MHS, Adam D. Devore, MD, Chetan B. Patel, MD, Jeffrey E. Keenan, MD, Carmelo A. Milano, MD, Jacob N. Schroder, MD

“…Objective: Randomized data support transplantation of hearts from donors after circulatory death. This may lead to a sizeable increase in the donor pool…”
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Heart transplant advances: Ex vivo organ-preservation systemsCentral Message by Benjamin S. Bryner, MD, Jacob N. Schroder, MD, Carmelo A. Milano, MD

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Trends and outcomes of patients with adult congenital heart disease and pulmonary hypertension listed for orthotopic heart transplantation in the United States by Krishnamurthy, Yamini, BA, Cooper, Lauren B., MD, Lu, Di, MS, Schroder, Jacob N., MD, Daneshmand, Mani A., MD, Rogers, Joseph G., MD, Milano, Carmelo A., MD, Hernandez, Adrian F., MD, MHS, Patel, Chetan B., MD

“…Background Heart transplantation is increasing in patients with adult congenital heart disease (ACHD). In this population, the association of pulmonary…”
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Improved Early Survival With a Nonsternotomy Approach for Continuous-Flow Left Ventricular Assist Device Replacement by Schechter, Matthew A., MD, Patel, Chetan B., MD, Blue, Laura J., NP, Welsby, Ian, MD, Rogers, Joseph G., MD, Schroder, Jacob N., MD, Milano, Carmelo A., MD

“…Background Even in the modern era of continuous-flow left ventricular assist devices (CF LVADs), device replacement may be required. Nonsternotomy (NS)…”
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Prolonged pulmonary support after cardiac surgery: incidence, risk factors and outcomes: a retrospective cohort study by Bartz, Raquel R., MD, MMCi, Ferreira, Renata G., MD, Schroder, Jacob N., MD, Davies, John, BSc, Liu, Wen-Wei, BSc, Camara, Andre, MD, Welsby, Ian J., MD

“…Abstract Background Post–cardiac surgery pulmonary dysfunction may be underreported. Therefore, we evaluated associated risk factors for prolonged pulmonary…”
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Variation among organ procurement organizations in experience and practice of heart donation after circulatory deathCentral Message by Austin Ayer, BS, Benjamin S. Bryner, MD, MS, Chetan B. Patel, MD, Jacob N. Schroder, MD, Carmelo A. Milano, MD, Muath A. Bishawi, MD, PhD, Sarah Casalinova, BS, Adam D. DeVore, MD, MHS

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Usefulness of two Centrifugal Ventricular Assist Devices in a Total Artificial Heart Configuration: A Preliminary Report by Mulvihill, Michael S., MD, Joseph, Jeremy T, MS, Daneshmand, Mani A., MD, Patel, Chetan B., MD, Milano, Carmelo A., MD, Schroder, Jacob N., MD

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