Search Results - "Schröder, Rafael"

Curcumin-loaded lipid-core nanocapsules as a strategy to improve pharmacological efficacy of curcumin in glioma treatment by Zanotto-Filho, Alfeu, Coradini, Karine, Braganhol, Elizandra, Schröder, Rafael, de Oliveira, Cláudia Melo, Simões-Pires, André, Battastini, Ana Maria Oliveira, Pohlmann, Adriana Raffin, Guterres, Sílvia Stanisçuaski, Forcelini, Cassiano Mateus, Beck, Ruy Carlos Ruver, Moreira, José Cláudio Fonseca

“…Curcumin-loaded lipid-core nanocapsules reduce tumor size in animal model of glioma. In this study, we developed curcumin-loaded lipid-core nanocapsules…”
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Comparison between proliferative and neuron-like SH-SY5Y cells as an in vitro model for Parkinson disease studies by Lopes, Fernanda Martins, Schröder, Rafael, Júnior, Mário Luiz Conte da Frota, Zanotto-Filho, Alfeu, Müller, Carolina Beatriz, Pires, André Simões, Meurer, Rosalva Thereza, Colpo, Gabriela Delevati, Gelain, Daniel Pens, Kapczinski, Flávio, Moreira, José Cláudio Fonseca, Fernandes, Marilda da Cruz, Klamt, Fabio

“…Abstract The molecular mechanisms underlying the cellular lost found in the nigrostriatal pathway during the progression of Parkinson's disease (PD) are not…”
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The curry spice curcumin selectively inhibits cancer cells growth in vitro and in preclinical model of glioblastoma by Zanotto-Filho, Alfeu, Braganhol, Elizandra, Edelweiss, Maria Isabel, Behr, Guilherme A, Zanin, Rafael, Schröder, Rafael, Simões-Pires, André, Battastini, Ana Maria Oliveira, Moreira, José Cláudio Fonseca

“…Previous studies suggested that curcumin is a potential agent against glioblastomas (GBMs). However, the in vivo efficacy of curcumin in gliomas remains not…”
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Sphingosines Derived from Marine Sponge as Potential Multi-Target Drug Related to Disorders in Cancer Development by Biegelmeyer, Renata, Schröder, Rafael, Rambo, Douglas F, Dresch, Roger R, Carraro, João L F, Mothes, Beatriz, Moreira, José Cláudio F, Junior, Mário L C da Frota, Henriques, Amélia T

“…Haliclona tubifera, marine sponge species abundant in Brazilian coastline, presents only a few papers published in the literature. Recently, we have reported…”
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The pharmacological NFκB inhibitors BAY117082 and MG132 induce cell arrest and apoptosis in leukemia cells through ROS-mitochondria pathway activation by Zanotto-Filho, Alfeu, Delgado-Cañedo, Andrés, Schröder, Rafael, Becker, Matheus, Klamt, Fábio, Moreira, José Cláudio Fonseca

“…Abstract A growing body of evidence suggests the inhibition of NFκB as a strategy to induce cell death in tumor cells. In this work, we evaluated the effects…”
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Antinociceptive Activity and Redox Profile of the Monoterpenes (+)-Camphene, p-Cymene, and Geranyl Acetate in Experimental Models by Quintans-Júnior, Lucindo, Moreira, José C. F., Pasquali, Matheus A. B., Rabie, Soheyla M. S., Pires, André S., Schröder, Rafael, Rabelo, Thallita K., Santos, João P. A., Lima, Pollyana S. S., Cavalcanti, Sócrates C. H., Araújo, Adriano A. S., Quintans, Jullyana S. S., Gelain, Daniel P.

“…Objective. To evaluate antinocicpetive and redox properties of the monoterpenes (+)-camphene, p-cymene, and geranyl acetate in in vivo and in vitro…”
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Xanthine oxidase-dependent ROS production mediates vitamin A pro-oxidant effects in cultured Sertoli cells by Zanotto-Filho, Alfeu, Schröder, Rafael, Moreira, José Cláudio F

“…Several studies have suggested that vitamin A (retinol, ROH) presents pro-oxidant properties in biological systems. Recent studies point out that xantine…”
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Cytotoxic effects on tumour cell lines of fatty acids from the marine sponge Scopalina ruetzleri by Biegelmeyer, Renata, Schröder, Rafael, Rambo, Douglas F., Dresch, Roger R., Stout, E. Paige, Carraro, João L.F., Mothes, Beatriz, Moreira, José C.F., Molinski, Tadeusz F., da Frota Junior, Mário L.C., Henriques, Amélia T.

“…Objectives Marine sponges are among the most promising sources of chemically diversified fatty acids (FAs). In addition, several studies have shown the effect…”
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NFκB inhibitors induce cell death in glioblastomas by Zanotto-Filho, Alfeu, Braganhol, Elizandra, Schröder, Rafael, de Souza, Luís Henrique T., Dalmolin, Rodrigo J.S., Pasquali, Matheus A. Bittencourt, Gelain, Daniel Pens, Battastini, Ana Maria Oliveira, Moreira, José Cláudio Fonseca

“…Identification of novel target pathways in glioblastoma (GBM) remains critical due to poor prognosis, inefficient therapies and recurrence associated with…”
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pH-dependent cytotoxic effects of extracts of the marine sponge Polymastia janeirensis on cancer cell lines by Biegelmeyer, Renata, Schröder, Rafael, Rambo, Douglas F., Dresch, Roger R., Carraro, João L. F., Mothes B, Beatriz, Moreira, José Cláudio F., da Frota Junior, Mario L. C., Henriques, Amélia T.

“…The purpose of this work was to study the cytotoxic effects of marine sponge Polymastia janeirensis, which has been observed in the field to release an orange…”
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Differential effects of retinol and retinoic acid on cell proliferation: a role for reactive species and redox-dependent mechanisms in retinol supplementation by Zanotto-Filho, Alfeu, Schröder, Rafael, Moreira, José Cláudio F

“…While some authors suggest that retinoids are potential anti-proliferative and antioxidant agents, evidence has suggested those present pro-oxidant properties,…”
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Cytotoxic effects on tumour cell lines of fatty acids from the marine sponge S copalina ruetzleri by Biegelmeyer, Renata, Schröder, Rafael, Rambo, Douglas F, Dresch, Roger R, Stout, E Paige, Carraro, João L F, Mothes, Beatriz, Moreira, José C F, Molinski, Tadeusz F, da Frota Junior, Mário L C, Henriques, Amélia T

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The pharmacological NF[kappa]B inhibitors BAY117082 and MG132 induce cell arrest and apoptosis in leukemia cells through ROS-mitochondria pathway activation by Zanotto-Filho, Alfeu, Delgado-Cañedo, Andrés, Schröder, Rafael, Becker, Matheus, Klamt, Fábio, Moreira, José Cláudio Fonseca

“…A growing body of evidence suggests the inhibition of NFκB as a strategy to induce cell death in tumor cells. In this work, we evaluated the effects of the…”
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The NFκB-mediated control of RS and JNK signaling in vitamin A-treated cells: Duration of JNK–AP-1 pathway activation may determine cell death or proliferation by Zanotto-Filho, Alfeu, Gelain, Daniel P., Schröder, Rafael, Souza, Luís F., Pasquali, Matheus A.B., Klamt, Fábio, Moreira, José Cláudio F.

“…Nuclear factor kappa B (NFκB) has emerged as a crucial regulator of cell survival, playing important functions in cellular resistance to oxidants and…”
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Changes in lymphocyte HSP70 levels in women handball players throughout 1 year of training: the role of estrogen levels by Weber, Maria Helena, da Rocha, Ricardo Fagundes, Schnorr, Carlos Eduardo, Schröder, Rafael, Moreira, José Cláudio Fonseca

“…Heat shock protein 70 (HSP70) is a chaperone that maintains protein conformation during heat stress. It has recently been observed that HSP70 may be released…”
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NFKB inhibitors induce cell death in glioblastomas by ZANOTTO, Alfeu, BRAGANHOL, Elizandra, SCHRÖDER, Rafael, DE SOUZA, Luís Henrique T, DALMOLIN, Rodrigo J. S, BITTENCOURT PASQUALI, Matheus A, PENS GELAIN, Daniel, BATTASTINI, Ana Maria Oliveira, FONSECA MOREIRA, José Cláudio

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The NFKB-mediated control of RS and JNK signaling in vitamin A-treated cells : Duration of JNK-AP-1 pathway activation may determine cell death or proliferation by ZANOTTO, Alfeu, GELAIN, Daniel P, SCHRÖDER, Rafael, SOUZA, Lufs F, PASQUALI, Matheus A. B, KLAMT, Fdbio, MOREIRA, José Claudio F

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First Fatal Cases due to Escherichia coli O157 and Campylobacter jejuni subsp. jejuni Outbreak Occurred in Southern Brazil by W Bartz, Felipe, Teixeira, Lilian B, Schroder, Rafael, Das Mercês Santos, André Felipe, Trindade, Priscila, Tondo, Eduardo Cesar

“…In December 2019, four children of the same school were hospitalized due to severe diarrhea, vomiting, and fever, and the mother of one child was diagnosed…”
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The pharmacological NFkappaB inhibitors BAY117082 and MG132 induce cell arrest and apoptosis in leukemia cells through ROS-mitochondria pathway activation by Zanotto-Filho, Alfeu, Delgado-Cañedo, Andrés, Schröder, Rafael, Becker, Matheus, Klamt, Fábio, Moreira, José Cláudio Fonseca

“…A growing body of evidence suggests the inhibition of NFkappaB as a strategy to induce cell death in tumor cells. In this work, we evaluated the effects of the…”
Get full text