Search Results - "Schowalter, David B."

Biochemical Correction of Very Long–chain Acyl-CoA Dehydrogenase Deficiency Following Adeno-associated Virus Gene Therapy by Merritt, J. Lawrence, Nguyen, Tien, Daniels, Jan, Matern, Dietrich, Schowalter, David B.

“…We report the development of a gene replacement strategy for very long–chain acyl-CoA dehydrogenase (VLCAD) deficiency. VLCAD is a mitochondrial enzyme…”
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The kinetics of rAAV integration in the liver by Miao, Carol H, Snyder, Richard O, Schowalter, David B, Patijn, Gijsbert A, Donahue, Brian, Winther, Brian, Kay, Mark A

“…Recombinant AAV vectors have been developed which lack all viral coding sequences, thus eliminating the potential of immune responses toward viral proteins…”
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Prairie dogs, cattle subsidies and alternative prey: seasonal and spatial variation in coyote diet in a temperate grassland by Lingle, Susan, Breiter, C‐Jae, Schowalter, David B., Wilmshurst, John F.

“…As the dominant predator on North America's grasslands, coyotes Canis latrans have a large influence on biodiversity, both on working ranches and in protected…”
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Congenital and Idiopathic Scoliosis: Clinical and Genetic Aspects by Giampietro, Philip F, Blank, Robert D, Raggio, Cathleen L, Merchant, Sajid, Jacobsen, F Stig, Faciszewski, Thomas, Shukla, Sanjay K, Greenlee, Anne R, Reynolds, Cory, Schowalter, David B

“…Genetic and environmental factors influencing spinal development in lower vertebrates are likely to play a role in the abnormalities associated with human…”
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In vitro correction of medium chain acyl CoA dehydrogenase deficiency with a recombinant adenoviral vector by Schowalter, David B., Matern, Dietrich, Vockley, Jerry

“…Defects of mitochondrial β-oxidation are a growing group of disorders with variable clinical presentations ranging from mild hypotonia to sudden infant death…”
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Subtelomeric deletions of chromosome 9q: A novel microdeletion syndrome by Stewart, Douglas R., Huang, Alina, Faravelli, Francesca, Anderlid, Britt-Marie, Medne, Livija, Ciprero, Karen, Kaur, Maninder, Rossi, Elena, Tenconi, Romano, Nordenskjöld, Magnus, Gripp, Karen W., Nicholson, Linda, Meschino, Wendy S., Capua, Esther, Quarrell, Oliver W.J., Flint, Jonathon, Irons, Mira, Giampietro, Philip F., Schowalter, David B., Zaleski, Christina A., Malacarne, Michela, Zackai, Elaine H., Spinner, Nancy B., Krantz, Ian D.

“…Fluorescent in situ hybridization (FISH) screening of subtelomeric rearrangements has resulted in the identification of previously unrecognized chromosomal…”
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In vitro characterization and in vivo expression of human very-long chain acyl-CoA dehydrogenase by Merritt, J. Lawrence, Matern, Dietrich, Vockley, Jerry, Daniels, Jan, Nguyen, Tien V., Schowalter, David B.

“…Very long-chain acyl-CoA dehydrogenase (VLCAD) deficiency is a disorder of fatty acid beta-oxidation that can present at any age with cardiomyopathy,…”
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232. Short_Term, In Vivo Correction of VLCAD Deficiency in Mice: Steps toward a Gene Therapy for Cardiomyopathy by Nguyen, Tien, Daniels, Jan, Merritt, Lawrence, Matern, Dietrich, Vockley, Jerry, Wood, Philip A., Schowalter, David B.

“…Cardiomyopathy is an important cause of morbidity and mortality in children. Deficiency of very-long-chain acyl-CoA dehydrogenase (VLCAD), one of several…”
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Implication of Interfering Antibody Formation and Apoptosis as Two Different Mechanisms Leading to Variable Duration of Adenovirus-Mediated Transgene Expression in Immune-Competent Mice by Schowalter, D B, Himeda, C L, Winther, B L, Wilson, C B, Kay, M A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Role of Immune Response and Immune Tolerization in Long-Term In Vivo Gene Expression Mediated by the Sleeping Beauty Transposon System by Podetz-Pedersen, Kelly M, Russell, Stephen J, Schowalter, David B, Somia, Nikunj V, McIvor, R Scott

“…The Sleeping Beauty (SB) transposon system in conjunction with rapid, high volume (hydrodynamic) DNA delivery has been demonstrated to achieve long-term gene…”
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Gene therapy: a status report by Schowalter, D B, Kay, M A

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Hepatocyte growth factor induces hepatocyte proliferation in vivo and allows for efficient retroviral‐mediated gene transfer in mice by Patijn, Gijsbert A., Lieber, Andre, Schowalter, David B., Schwall, Ralph, Kay, Mark A.

“…Recombinant retroviral vectors are an attractive means of transferring genes into the liver because they integrate into the host cell genome and result in…”
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108. In Vitro Down-Regulation of Transgene Expression with Cre/loxP Mediated Recombination by Ii, J Lawrence Merritt, Daniels, Jan, Schowalter, David B

“…Safe and durable transgene expression for the treatment of hepatic diseases has been reported utilizing several different viral vector systems. Following gene…”
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Chemical and catalytic properties of the peroxisomal acyl-coenzyme A oxidase from Candida tropicalis by Coudron, P E, Frerman, F E, Schowalter, D B

“…The peroxisomal acyl-CoA oxidase has been purified from extracts of the yeast Candida tropicalis grown with alkanes as the principal energy source. The enzyme…”
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438. In Vitro Studies Towards the Development of a Recombinant Adeno-Associated Virus for the Treatment of Medium-Chain Acyl-CoA Dehydrogenase Deficiency by Merritt, J Lawrence, Matern, Dietrich, Vockley, Jerry, Huey, Joeseph, Schowalter, David B

“…Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency is the most commonly diagnosed inborn error of metabolism. Clinical presentation ranges from mild…”
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The generation of radiolabeled DNA and RNA probes with polymerase chain reaction by Schowalter, D B, Sommer, S S

“…By including a radioactive triphosphate during polymerase chain reaction (PCR), probes of very high specific activity can be generated. The advantages of PCR…”
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A field and laboratory evaluation of capture biases of two small mammal live traps by Schowalter, David B

“…Sherman and Ugglan small mammal live traps are widely used in North America and Europe. The success of the two types of trap, which has not been previously…”
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Reconstitution of progesterone receptor with heat shock proteins by Smith, D F, Schowalter, D B, Kost, S L, Toft, D O

“…Nonactivated chick progesterone receptor from hypotonic tissue extracts exists in a large complex containing the heat shock proteins hsp90 and hsp70 plus…”
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Characterization of progesterone receptor binding to the 90- and 70-kDa heat shock proteins by Schowalter, D.B., Sullivan, W.P., Maihle, N.J., Dobson, A.D., Conneely, O.M., O'Malley, B.W., Toft, D.O.

“…In this study a model system for expression of the chicken progesterone receptor in cultured cells was developed using a quail fibroblast cell line, QT6. The…”
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Swarming, Reproduction, and Early Hibernation of Myotis lucifugus and M. volans in Alberta, Canada by Schowalter, David B.

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