Search Results - "Schouten, P C"

BRCA1-like profile is not significantly associated with survival benefit of non-myeloablative intensified chemotherapy in the GAIN randomized controlled trial by van Rossum, A. G. J., Schouten, P. C., Weber, K. E., Nekljudova, V., Denkert, C., Solbach, C., Köhne, C. H., Thomssen, C., Forstbauer, H., Hoffmann, G., Kohls, A., Schmatloch, S., Schem, C., von Minckwitz, G., Karn, T., Möbus, V. J., Linn, S. C., Loibl, S., Marmé, F.

“…Purpose The BRCA1 -like profile identifies tumors with a defect in homologous recombination due to inactivation of BRCA1. This profile has been shown to…”
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Mammary gland-specific ablation of focal adhesion kinase reduces the incidence of p53-mediated mammary tumour formation by van Miltenburg, M H A M, van Nimwegen, M J, Tijdens, I, Lalai, R, Kuiper, R, Klarenbeek, S, Schouten, P C, de Vries, A, Jonkers, J, van de Water, B

“…Background: Elevated expression of focal adhesion kinase (FAK) occurs in numerous human cancers including colon-, cervix- and breast cancer. Although several…”
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Understanding the biology of triple-negative breast cancer by Criscitiello, C, Azim, Jr, H A, Schouten, P C, Linn, S C, Sotiriou, C

“…Greater understanding of the biology of triple-negative breast cancer (TNBC) is needed to discern the roughly 60% of node-negative patients who are already…”
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Understanding the biology of triple-negative breast cancer by Criscitiello, C., Azim, H.A., Schouten, P.C., Linn, S.C., Sotiriou, C.

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Understanding the biology of triple-negative breast cancer: Triple-negative breast cancer in focus: From biology to novel therapeutics by CRISCITIELLO, C, AZIM, H. A, SCHOUTEN, P. C, LINN, S. C, SOTIRIOU, C

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Expression of XIST and 53BP1 as Predictive Markers in BRCA1 Deficient Breast Cancer by Schouten, P.C., Vollebergh, M.A., Opdam, M., Jonkers, M., Loden, M., Wesseling, J., Linn, S.C.

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Abstract OT1-03-10: A phase I followed by a r andomiz e d phase II trial of two cycles carboplatin-olaparib followed by olaparib monotherapy v ersus capec i tabine in BRCA-1 or -2 mutated Her2 negative ad v anced breast c a ncer as first l ine treatment (REVIVAL study) by Dackus, GMHE, Schouten, PC, Geenen, JJ, Marchetti, S, Sonke, GS, Linn, SC, Schellens, JHM

“…Background Preclinical studies revealed that the combination of platinum compounds and olaparib is additive and possibly even synergistic in cell models with…”
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Abstract P3-07-28: BRCA1-like profile as predictive biomarker in non myeloablative chemotherapy (GAIN study) by van Rossum, AGJ, Schouten, PC, Weber, KE, Nekljudova, V, Denkert, C, von Minckwitz, G, Karn, T, Möbus, VJ, Linn, SC, Loibl, S, Marmé, F

“…Background: The BRCA1-like copy number (CN) profile can be used as a biomarker to predict which stage III breast cancer patients benefit from myeloablative,…”
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Abstract PD3-01: CDK7: A marker of poor prognosis and tractable therapeutic target in triple-negative breast cancer by Gallagher, WM, Li, B, Ni Chonghaile, T, Fan, Y, Klinger, R, O'Connor, AE, Conroy, E, Tarrant, F, O'Hurley, G, Mallya Udupi, G, Gaber, A, Chin, S-F, Schouten, PC, Dubois, T, Linn, S, Jirstrom, K, Caldas, C, Bernards, R, O'Connor, DP

“…Triple-negative breast cancer (TNBC) is defined by absent expression of estrogen receptor (ER), progesterone receptor (PR) and non-overexpression of human…”
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EZH2 is overexpressed in breast tumors with a BRCA1-like DNA copy number profile by Puppe, J, Opdam, M, Jozwiak, K, Schouten, PC, Rodenhuis, S, Hauptmann, M, Hahnen, E, Mallmann, P, Schmutzler, R, Linn, S, Jonkers, J

“…Purpose: The polycomb group protein EZH2 is an epigenetic repressor and overexpression of EZH2 is associated with highly aggressive types of breast cancer…”
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EZH2 is overexpressed in breast tumors with a BRCA1-like DNA copy number profile by Puppe, J, Opdam, M, Jozwiak, K, Schouten, PC, Rodenhuis, S, Hauptmann, M, Hahnen, E, Mallmann, P, Schmutzler, R, Linn, S, Jonkers, J

“…Abstract only…”
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Effects of zinc contamination on a natural nematode community in outdoor soil mesocosms by SMIT, C. E, SCHOUTEN, A. J, VAN DEN BRINK, P. J, VAN ESBROEK, M. L. P, POSTHUMA, L

“…The effect of zinc on the indigenous nematode fauna of a sandy soil was determined in an experimentally contaminated outdoor field plot. The aims of the study…”
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