Search Results - "Schotten, U."

Current controversies in determining the main mechanisms of atrial fibrillation by Schotten, U., Dobrev, D., Platonov, P. G., Kottkamp, H., Hindricks, G.

“…Despite considerable basic research into the mechanisms of atrial fibrillation (AF), not much progress has been made in the prognosis of patients with AF. With…”
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Post-operative atrial fibrillation: a maze of mechanisms by Maesen, Bart, Nijs, Jan, Maessen, Jos, Allessie, Maurits, Schotten, Ulrich

“…Post-operative atrial fibrillation (POAF) is one of the most frequent complications of cardiac surgery and an important predictor of patient morbidity as well…”
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Pleiotropic effects of factor Xa and thrombin: what to expect from novel anticoagulants by Spronk, Henri M H, de Jong, Anne Margreet, Crijns, Harry J, Schotten, Ulrich, Van Gelder, Isabelle C, Ten Cate, Hugo

“…Factor Xa and thrombin are well-known components of the coagulation cascade and have been proven to be viable targets for effective anticoagulation treatment…”
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Alterations of atrial Ca2+ handling as cause and consequence of atrial fibrillation by Greiser, M., Lederer, W. J., Schotten, U.

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Pathophysiology of idiopathic atrial fibrillation - prognostic and treatment implications by Weijs, B, Schotten, U, Crijns, H J G M

“…The term idiopathic or lone atrial fibrillation (AF) is commonly used in the young and apparently healthy individual who suffers from AF. Although there is…”
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JavaCyte, a novel open-source tool for automated quantification of key hallmarks of cardiac structural remodeling by Winters, J., von Braunmuhl, M. Edler, Zeemering, S., Gilbers, M., Brink, T. Ten, Scaf, B., Guasch, E., Mont, L., Batlle, M., Sinner, M., Hatem, S., Mansour, M. K., Fabritz, L., Sommerfeld, L. C., Kirchhof, P., Isaacs, A., Stoll, M., Schotten, U., Verheule, S.

“…Many cardiac pathologies involve changes in tissue structure. Conventional analysis of structural features is extremely time-consuming and subject to observer…”
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Comprehensive risk reduction in patients with atrial fibrillation: emerging diagnostic and therapeutic options-a report from the 3rd Atrial Fibrillation Competence NETwork/European Heart Rhythm Association consensus conference by Kirchhof, Paulus, Lip, Gregory Y.H., Van Gelder, Isabelle C., Bax, Jeroen, Hylek, Elaine, Kaab, Stefan, Schotten, Ulrich, Wegscheider, Karl, Boriani, Giuseppe, Brandes, Axel, Ezekowitz, Michael, Diener, Hans, Haegeli, Laurent, Heidbuchel, Hein, Lane, Deirdre, Mont, Luis, Willems, Stephan, Dorian, Paul, Aunes-Jansson, Maria, Blomstrom-Lundqvist, Carina, Borentain, Maria, Breitenstein, Stefanie, Brueckmann, Martina, Cater, Nilo, Clemens, Andreas, Dobrev, Dobromir, Dubner, Sergio, Edvardsson, Nils G., Friberg, Leif, Goette, Andreas, Gulizia, Michele, Hatala, Robert, Horwood, Jenny, Szumowski, Lukas, Kappenberger, Lukas, Kautzner, Josef, Leute, Angelika, Lobban, Trudie, Meyer, Ralf, Millerhagen, Jay, Morgan, John, Muenzel, Felix, Nabauer, Michael, Baertels, Christoph, Oeff, Michael, Paar, Dieter, Polifka, Juergen, Ravens, Ursula, Rosin, Ludger, Stegink, W., Steinbeck, Gerhard, Vardas, Panos, Vincent, Alphons, Walter, Maureen, Breithardt, Günter, Camm, A. John

“…While management of atrial fibrillation (AF) patients is improved by guideline-conform application of anticoagulant therapy, rate control, rhythm control, and…”
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Mapping of atrial fibrillation - basic research and clinical applications by Schotten, U

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Smartphone and wearable detected atrial arrhythmias in Older Adults: Results of a fully digital European Case finding study by Fabritz, L, Connolly, D L, Czarnecki, E, Dudek, D, Guasch, E, Haase, D, Huebner, T, Zlahoda-Huzior, A, Jolly, K, Kirchhof, P, Obergassel, J, Schotten, U, Vettorazzi, E, Winkelmann, S J, Zapf, A, Schnabel, R B

“…Simplified detection of atrial arrhythmias via consumer-electronics would enable earlier therapy in at-risk populations. Whether this is feasible and effective…”
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Reappraisal of Atrial fibrillation: interaction between hyperCoagulability, Electrical remodelling and Vascular destabilisation in the progression of AF (RACE V) Tissue Bank Project: study design by Gilbers, M. D., Bidar, E., Maesen, B., Zeemering, S., Isaacs, A., Crijns, H., van Gelder, I., Rienstra, M., Verheule, S., Maessen, J., Stoll, M., Schotten, U.

“…Background The development of atrial fibrillation (AF) is a complex multifactorial process. Over the past few decades, much has been learned about the…”
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Tailored treatment strategies: a new approach for modern management of atrial fibrillation by Gelder, I. C., Hobbelt, A. H., Marcos, E. G., Schotten, U., Cappato, R., Lewalter, T., Schwieler, J., Rienstra, M., Boriani, G.

“…Atrial fibrillation (AF) is not benign. Cardiovascular diseases and risk factors differ importantly amongst patients. Careful phenotyping with the aim to start…”
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"Early" class III drugs for the treatment of atrial fibrillation: efficacy and atrial selectivity of AVE0118 in remodeled atria of the goat by Blaauw, Y, Gögelein, H, Tieleman, R G, van Hunnik, A, Schotten, U, Allessie, M A

“…Currently available antiarrhythmic drugs are only moderately effective against atrial fibrillation (AF) and may cause ventricular proarrhythmia. AVE0118 is a…”
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Cardioversion of persistent atrial fibrillation by a combination of atrial specific and non-specific class III drugs in the goat by BLAAUW, Y, SCHOTTEN, U, VAN HUNNIK, A, NEUBERGER, H. R, ALLESSIE, M. A

“…In electrically remodeled atria the effect of blockers of the delayed rectifier K+ current I(Kr) on repolarization is reduced, whereas the efficacy of 'early'…”
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Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): Standardised reporting for model reproducibility, interoperability, and data sharing by Quinn, T.A., Granite, S., Allessie, M.A., Antzelevitch, C., Bollensdorff, C., Bub, G., Burton, R.A.B., Cerbai, E., Chen, P.S., Delmar, M., DiFrancesco, D., Earm, Y.E., Efimov, I.R., Egger, M., Entcheva, E., Fink, M., Fischmeister, R., Franz, M.R., Garny, A., Giles, W.R., Hannes, T., Harding, S.E., Hunter, P.J., Iribe, G., Jalife, J., Johnson, C.R., Kass, R.S., Kodama, I., Koren, G., Lord, P., Markhasin, V.S., Matsuoka, S., McCulloch, A.D., Mirams, G.R., Morley, G.E., Nattel, S., Noble, D., Olesen, S.P., Panfilov, A.V., Trayanova, N.A., Ravens, U., Richard, S., Rosenbaum, D.S., Rudy, Y., Sachs, F., Sachse, F.B., Saint, D.A., Schotten, U., Solovyova, O., Taggart, P., Tung, L., Varró, A., Volders, P.G., Wang, K., Weiss, J.N., Wettwer, E., White, E., Wilders, R., Winslow, R.L., Kohl, P.

“…Cardiac experimental electrophysiology is in need of a well-defined Minimum Information Standard for recording, annotating, and reporting experimental data. As…”
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Opportunities and challenges of current electrophysiology research: a plea to establish 'translational electrophysiology' curricula by Lau, Dennis H, Volders, Paul G A, Kohl, Peter, Prinzen, Frits W, Zaza, Antonio, Kääb, Stefan, Oto, Ali, Schotten, Ulrich

“…Cardiac electrophysiology has evolved into an important subspecialty in cardiovascular medicine. This is in part due to the significant advances made in our…”
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Stroke risk in patients with device-detected atrial high-rate episodes by Erküner, Ö., Rienstra, M., Van Gelder, I. C., Schotten, U., Crijns, H. J. G. M., Luermans, J. G. L. M.

“…Cardiovascular implantable electronic devices (CIEDs) can detect atrial arrhythmias, i. e. atrial high-rate episodes (AHRE). The thrombo-embolic risk in…”
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Atrial fibrillation-induced atrial contractile dysfunction: a tachycardiomyopathy of a different sort by SCHOTTEN, Ulrich, GREISER, Maura, BENKE, Dirk, BUERKEL, Kai, EHRENTEIDT, Britta, STELLBRINK, Christoph, VAZQUEZ-JIMENEZ, Jaime F, SCHOENDUBE, Friedrich, HANRATH, Peter, ALLESSIE, Maurits

“…Although AF-induced atrial contractile dysfunction has significant clinical implications the underlying intracellular mechanisms are poorly understood. From…”
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Measured and simulated P waves in normal subjects reflect complex atrial anatomy by Potse, M, Lankveld, T.A.R, Zeemering, S, Kuijpers, N.H.L, Schotten, U

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HIPSC model reveals M1 macrophages cause atrial arrhythmia correlated to electrophysiological remodelling of atrial cardiomyocytes in 2D and 3D engineered heart tissue by Hutschalik, T, Schotten, U, Matsa, E

“…Abstract Atrial fibrillation (AF) is the most common sustained arrhythmia with an estimated prevalence of 1.5–2%. Current treatments lack effectiveness and do…”
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Corrigendum to: Cardioversion of persistent atrial fibrillation by a combination of atrial specific and non-specific class III drugs in the goat [Cardiovascular Research 75 (2007) 89–98] by Blaauw, Y., Schotten, U., van Hunnik, A., Neuberger, H.R., Allessie, M.A.

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