Search Results - "Schottelius, D D"
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Surface characterization of activated charcoal by X-ray photoelectron spectroscopy (XPS) : correlation with phenobarbital adsorption data
Published in Pharmaceutical research (1992)“…X-ray photoelectron spectroscopy (XPS) was used to identify the functional states of carbon existing on the surfaces of various activated charcoals. The…”
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Phenytoin pharmacokinetics: before and after folic acid administration
Published in Epilepsia (Copenhagen) (01-07-1992)“…Phenytoin (PHT) exhibits linear and Michaelis-Menten pharmacokinetics. PHT decreases serum folate; the vitamin folic acid (FA) is hypothesized to be a cofactor…”
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3
Model selection for the adsorption of phenobarbital by activated charcoal
Published in Pharmaceutical research (01-02-1991)“…Activated charcoal is known to adsorb a wide variety of substances from solution, and several equations have been used to fit the resulting adsorption data…”
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Phenobarbital removal characteristics of three brands of activated charcoals : a system analysis approach
Published in Pharmaceutical research (01-02-1994)“…The in vivo phenobarbital removal characteristics of three brands of activated charcoal (Actidose, Charcoaid, Superchar) were studied in normal volunteers…”
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Effect of charcoal and sorbitol-charcoal suspension on the elimination of intravenous phenobarbital
Published in Therapeutic drug monitoring (01-03-1987)“…The effects of two different oral charcoal suspensions on the elimination of a 200 mg/70 kg, 1 h intravenous (i.v.) infusion of phenobarbital and the…”
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Decrease of serum folates in healthy male volunteers taking phenytoin
Published in Epilepsia (Copenhagen) (01-01-1988)“…The effect of phenytoin (PHT) on serum folate and the effect of additional oral folic acid (FA) on serum folate during continued treatment with PHT were…”
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Phenobarbital adsorption from simulated intestinal fluid U.S.P., and simulated gastric fluid, U.S.P., by two activated charcoals
Published in Pharmaceutical research (01-03-1988)“…Adsorption of phenobarbital from simulated intestinal and gastric fluids by two activated charcoals was studied. Adsorption isotherm data were analyzed by the…”
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Utilization of Km for phenytoin dosage after folate addition to patient regimen
Published in Therapeutic drug monitoring (01-09-1987)“…Phenytoin decreases serum and red blood cell folates in 50% of the patients on the anticonvulsant. The supplementation of folic acid changes the disposition of…”
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Phenytoin binding in healthy volunteers
Published in Therapeutic drug monitoring (01-12-1987)“…The pharmacologic effect of phenytoin is directly related to the unbound concentration in the serum, which previously has been reported in the literature to be…”
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Phenytoin-folic acid: a review
Published in Drug intelligence & clinical pharmacy (01-04-1984)“…The nutrient-drug interaction between folate and phenytoin is a two-way interaction. Folate deficiency resulting from long-term phenytoin therapy is a common…”
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Folic Acid improves Phenytoin Pharmacokinetics
Published in Journal of the American Dietetic Association (01-03-1995)“…Phenytoin (PHT) therapy to control seizures decreases serum folate levels in half of epileptic patients, thus increasing the risk of folate depletion…”
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Phenytoin and folic acid: individualized drug-drug interaction
Published in Therapeutic drug monitoring (01-01-1983)“…The effect of folic acid supplementation on the disposition of phenytoin and the resultant loss of seizure control in a male folate-deficient epileptic is…”
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Phenytoin and folic acid interaction: a preliminary report
Published in Therapeutic drug monitoring (01-01-1983)“…The effect of folic acid (1 mg/day orally) on phenytoin steady-state pharmacokinetics was studied in four male folate-deficient epileptic patients who were…”
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Decreased phenytoin levels in antineoplastic therapy
Published in Therapeutic drug monitoring (1979)“…A case history is reported illustrating the difficulties which may be encountered in maintaining seizure control in patients being treated with antineoplastic…”
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Late-onset thrombocytopenia with phenytoin therapy
Published in Annals of neurology (01-10-1979)Get more information
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Optimization of pharmacokinetic monitoring: I. Linear pharmacokinetics
Published in Therapeutic drug monitoring (1983)“…To reach and maintain therapeutic drug concentrations, reliable estimates of the parameters describing the pharmacokinetic behavior of the drug are required…”
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Linear systems approach to the analysis of an induced drug removal process. Phenobarbital removal by oral activated charcoal
Published in Journal of pharmacokinetics and biopharmaceutics (01-02-1986)“…The theory of linear systems analysis is applied to the evaluation of induced drug removal processes. The rate and extent of removal are determined by…”
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Use of phenytoin serum levels in a case of status epilepticus
Published in Neurology (01-09-1976)“…Serum anticonvulsant determinations made possible the identification of an unusual cause of status epilepticus and assisted with appropriate therapy in an…”
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Parkinsonism--drug treatment: Part I
Published in Drug intelligence & clinical pharmacy (01-01-1987)“…The purpose of this two-part review is to explain current drug treatment in part I and discuss investigational drug therapy and miscellaneous drugs in the…”
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Basal energy utilization in mammalian skeletal muscle
Published in Proceedings of the Society for Experimental Biology and Medicine (01-04-1968)Get more information
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