Search Results - "Schor, Nina Felice"
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The p75 neurotrophin receptor in human development and disease
Published in Progress in neurobiology (01-10-2005)“…The functional effects of nerve growth factor (NGF) and its precursor, pro-NGF, are thought to be mediated through binding of these ligands to one or both of…”
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p75NTR-dependent modulation of cellular handling of reactive oxygen species
Published in Journal of neurochemistry (01-07-2009)“…Our previous studies demonstrated that p75NTR confers protection against oxidative stress-induced apoptosis upon PC12 cells; however, the mechanisms…”
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Neuroprotective effects of TEMPOL in central and peripheral nervous system models of Parkinson's disease
Published in Biochemical pharmacology (01-11-2005)“…TEMPOL (4-hydroxy-2,2,6,6-tetramethylpiperidine- N-oxyl) is a stable nitroxyl antioxidant. Previous studies have suggested that TEMPOL is protective in acute…”
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Toward the definition of acute disseminated encephalitis of childhood
Published in Current opinion in pediatrics (01-12-2004)“…Acute disseminated encephalomyelitis (ADEM) is a demyelinating disorder most common in childhood and adolescence and thought to have an immune pathogenesis…”
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Role of caspase 3-dependent Bcl-2 cleavage in potentiation of apoptosis by Bcl-2
Published in Molecular pharmacology (01-01-2002)“…Previous studies from our laboratory have demonstrated that Bcl-2 has a proapoptotic effect on neocarzinostatin (NCS)-treated PC12 pheochromocytoma cells. In…”
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p75-nerve growth factor as an antiapoptotic complex: independence versus cooperativity in protection from enediyne chemotherapeutic agents
Published in Molecular pharmacology (01-04-2002)“…Growth factors, including nerve growth factor (NGF), have been hypothesized to play a role in resistance to chemotherapeutic agent-induced apoptosis. Induction…”
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Bcl-2-mediated potentiation of neocarzinostatin-induced apoptosis : requirement for caspase-3, sulfhydryl groups, and cleavable Bcl-2
Published in Cancer chemotherapy and pharmacology (01-03-2006)“…Overexpression of antiapoptotic Bcl-2 family members is thought to contribute to chemotherapeutic resistance of neural crest tumors. Paradoxical potentiation…”
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Methylation of DNA and chromatin as a mechanism of oncogenesis and therapeutic target in neuroblastoma
Published in Oncotarget (24-04-2018)“…Neuroblastoma (NB), a developmental cancer, is often fatal, emphasizing the need to understand its pathogenesis and identify new therapeutic targets. The…”
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Brain imaging and prophylactic therapy in children with migraine: recommendations versus reality
Published in The Journal of pediatrics (01-12-2003)“…To determine the concordance between referring physician behavior and published criteria for performance of imaging studies and institution of prophylactic…”
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The Scholarly Project Initiative: introducing scholarship in medicine through a longitudinal, mentored curricular program
Published in Academic medicine (01-09-2005)“…Many U.S. medical schools offer students the opportunity to undertake laboratory or clinical research or another form of scholarly project over the summer…”
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TrkA as a life and death receptor: Receptor dose as a mediator of function
Published in Cancer research (Chicago, Ill.) (01-09-2002)“…Nerve growth factor (NGF) has been implicated as both an inhibitor and an inducer of apoptosis. Binding of NGF to its TrkA receptor is generally considered to…”
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Bcl-2 overexpression disrupts the morphology of PC12 cells through reduced ERK activation
Published in Brain research (27-09-2006)“…Bcl-2 has been hypothesized to regulate many cellular functions in addition to its well-characterized role in the prevention of programmed cell death. To…”
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Clinical Pediatric Neurology: A Signs and Symptoms Approach, 3rd ed
Published in Neurology (01-07-1997)Get full text
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Introduction
Published in Seminars in pediatric neurology (01-06-2000)Get full text
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Bcl-2 mediates induction of neural differentiation
Published in Oncogene (21-08-2003)“…Bcl-2 is an antiapoptotic protein expressed in a wide variety of cell types. We have found that overexpression of bcl-2 in PC12 neural crest tumor cells leads…”
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Neurology of systemic autoimmune disorders: A pediatric perspective
Published in Seminars in pediatric neurology (01-06-2000)“…Autoimmune disorders can involve patients of any age and organs of any organ system. The central and peripheral nervous systems are frequently among the…”
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Neuroblastoma as a neurobiological disease
Published in Journal of neuro-oncology (1999)“…While neuroscientists are often involved in the assessment and care of patients with central nervous system tumors, they are only rarely involved in the case…”
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Interaction between 6-Hydroxydopamine and Transferrin: “Let My Iron Go”
Published in Biochemistry (Easton) (28-03-2000)“…The dopamine analogue 6-hydroxydopamine (6-OHDA) is selectively toxic to catecholaminergic neurons. Because of its selectivity for neuroblastic cells in the…”
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