Search Results - "Schooten, F. J."
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The potential of volatile organic compounds for the detection of active disease in patients with ulcerative colitis
Published in Alimentary pharmacology & therapeutics (01-05-2017)“…Summary Background To optimise treatment of ulcerative colitis (UC), patients need repeated assessment of mucosal inflammation. Current non‐invasive biomarkers…”
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Editorial: volatile organic compounds in breath for monitoring IBD—longitudinal studies are essential. Authors’ reply
Published in Alimentary pharmacology & therapeutics (01-08-2017)“…Linked Content This article is linked to Williams and Orchard, and Smolinska et al papers. To view these articles visit https://doi.org/10.1111/apt.14135 and…”
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Biomarkers for visceral hypersensitivity in patients with irritable bowel syndrome
Published in Neurogastroenterology and motility (01-12-2017)“…Background Increased visceral sensitivity is observed in up to 60% of patients with Irritable Bowel Syndrome (IBS). Mucosal inflammation, altered…”
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Breath analysis as a potential diagnostic tool for tuberculosis
Published in The international journal of tuberculosis and lung disease (01-06-2012)“…SETTING: Cape Town, South Africa.OBJECTIVES: We investigated the potential of breath analysis by gas chromatography-mass spectrometry (GC-MS) to discriminate…”
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Volatile organic compounds in breath as markers for irritable bowel syndrome: a metabolomic approach
Published in Alimentary pharmacology & therapeutics (01-07-2016)“…Background The diagnosis of irritable bowel syndrome (IBS) is challenging because of its heterogeneity and multifactorial pathophysiology. No reliable…”
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Comparing patterns of volatile organic compounds exhaled in breath after consumption of two infant formulae with a different lipid structure: a randomized trial
Published in Scientific reports (24-01-2019)“…Infant formulae have been used since decades as an alternative to or a complement to human milk. Human milk, the “gold standard” of infant nutrition, has been…”
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A profile of volatile organic compounds in breath discriminates COPD patients from controls
Published in Respiratory medicine (01-04-2010)“…Summary Background Chronic obstructive pulmonary disease (COPD) is an inflammatory condition characterized by oxidative stress and the formation of volatile…”
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Differences in Treatment Response in Bronchial Epithelial Cells from Idiopathic Pulmonary Fibrosis (IPF) Patients: A First Step towards Personalized Medicine?
Published in Antioxidants (01-02-2023)“…Idiopathic pulmonary fibrosis (IPF) has a detrimental prognosis despite antifibrotic therapies to which individual responses vary. IPF pathology is associated…”
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Development of accurate classification method based on the analysis of volatile organic compounds from human exhaled air
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (2008)“…Analysis of exhaled air leads to the development of fast accurate and non-invasive diagnostics. A comprehensive analysis of the entire range of volatile…”
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The use of exhaled air analysis in discriminating interstitial lung diseases: a pilot study
Published in Respiratory research (20-01-2022)“…Fibrotic Interstitial lung diseases (ILD) are a heterogeneous group of chronic lung diseases characterized by diverse degrees of lung inflammation and…”
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In vitro evaluation of baseline and induced DNA damage in human sperm exposed to benzo[a]pyrene or its metabolite benzo[a]pyrene-7,8-diol-9,10-epoxide, using the comet assay
Published in Mutagenesis (01-07-2010)“…Exposure to genotoxins may compromise DNA integrity in male reproductive cells, putting future progeny at risk for developmental defects and diseases. To study…”
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Volatile organic compounds in exhaled breath as a diagnostic tool for asthma in children
Published in Clinical and experimental allergy (01-01-2010)“…Summary Background The correct diagnosis of asthma in young children is often hard to achieve, resulting in undertreatment of asthmatic children and…”
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Genetic variation as a predictor of smoking cessation success. A promising preventive and intervention tool for chronic respiratory diseases?
Published in The European respiratory journal (01-03-2009)“…Tobacco smoking continues to be the largest preventable cause of premature morbidity and mortality throughout the world, including chronic respiratory diseases…”
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Identification of microorganisms based on headspace analysis of volatile organic compounds by gas chromatography-mass spectrometry
Published in Journal of breath research (01-06-2014)“…The identification of specific volatile organic compounds (VOCs) produced by microorganisms may assist in developing a fast and accurate methodology for the…”
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Inflammation-associated extracellular β-glucuronidase alters cellular responses to the chemical carcinogen benzo[a]pyrene
Published in Archives of toxicology (01-09-2016)“…Neutrophils infiltrate tissues during inflammation, and when activated, they release β-glucuronidase. Since inflammation is associated with carcinogenesis, we…”
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An abbreviated protocol for multilineage neural differentiation of murine embryonic stem cells and its perturbation by methyl mercury
Published in Reproductive toxicology (Elmsford, N.Y.) (01-07-2010)“…Alternative assays are highly desirable to reduce the extensive experimental animal use in developmental toxicity testing. In the present study, we developed…”
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Body size, physical activity, genetic variants in the insulin-like growth factor pathway and colorectal cancer risk
Published in Carcinogenesis (New York) (01-09-2015)“…Insulin-like growth factors (IGFs) have been associated with growth, body size, physical activity and colorectal cancer (CRC). We hypothesized that variants in…”
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Maternal intake of quercetin during gestation alters ex vivo benzo[a]pyrene metabolism and DNA adduct formation in adult offspring
Published in Mutagenesis (01-07-2012)“…Variation in xenobiotic metabolism cannot entirely be explained by genetic diversity in metabolic enzymes. We suggest that maternal diet during gestation can…”
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Comparison of multiple DNA adduct types in tumor adjacent human lung tissue: effect of cigarette smoking
Published in Carcinogenesis (New York) (01-12-2002)“…Cigarette smokers inhale a broad range of carcinogens derived from tobacco and its pyrolysis products, including free radicals, which induce oxidative stress…”
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Inflammation and the chemical carcinogen benzo[a]pyrene: Partners in crime
Published in Mutation research (01-10-2017)“…Exposure to benzo[a]pyrene (B[a]P) is known to play a role in lung carcinogenesis and the underlying processes can be modified by the presence of inflammation…”
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