Search Results - "Schoolcraft, Kathleen"

Assessing the role of serotonergic receptors in cannabidiol's anticonvulsant efficacy by Pelz, Madeline C, Schoolcraft, Kathleen D, Larson, Chloe, Spring, Mitchell G, López, Hassan H

“…Abstract Cannabidiol (CBD) is a phytocannabinoid that has demonstrated anticonvulsant efficacy in several animal models of seizure. The current experiment…”
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The effects of adolescent cannabinoid exposure on seizure susceptibility and lethality in adult male rats by Spring, Mitchell G, Schoolcraft, Kathleen D, López, Hassan H

“…Abstract There is substantial evidence in rodent models that chronic exposure to cannabinoids during adolescence can alter the development of neurobiological…”
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PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation by Khadka, Prasidda, Reitman, Zachary J., Lu, Sophie, Buchan, Graham, Gionet, Gabrielle, Dubois, Frank, Carvalho, Diana M., Shih, Juliann, Zhang, Shu, Greenwald, Noah F., Zack, Travis, Shapira, Ofer, Pelton, Kristine, Hartley, Rachel, Bear, Heather, Georgis, Yohanna, Jarmale, Spandana, Melanson, Randy, Bonanno, Kevin, Schoolcraft, Kathleen, Miller, Peter G., Condurat, Alexandra L., Gonzalez, Elizabeth M., Qian, Kenin, Morin, Eric, Langhnoja, Jaldeep, Lupien, Leslie E., Rendo, Veronica, Digiacomo, Jeromy, Wang, Dayle, Zhou, Kevin, Kumbhani, Rushil, Guerra Garcia, Maria E., Sinai, Claire E., Becker, Sarah, Schneider, Rachel, Vogelzang, Jayne, Krug, Karsten, Goodale, Amy, Abid, Tanaz, Kalani, Zohra, Piccioni, Federica, Beroukhim, Rameen, Persky, Nicole S., Root, David E., Carcaboso, Angel M., Ebert, Benjamin L., Fuller, Christine, Babur, Ozgun, Kieran, Mark W., Jones, Chris, Keshishian, Hasmik, Ligon, Keith L., Carr, Steven A., Phoenix, Timothy N., Bandopadhayay, Pratiti

“…The role of PPM1D mutations in de novo gliomagenesis has not been systematically explored. Here we analyze whole genome sequences of 170 pediatric high-grade…”
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ALK Amplification and Rearrangements Are Recurrent Targetable Events in Congenital and Adult Glioblastoma by Blandin, Anne-Florence, Giglio, Ross, Graham, Maya Srikanth, Garcia, Guadalupe, Malinowski, Seth, Woods, Jared K, Ramkissoon, Shakti, Ramkissoon, Lori, Dubois, Frank, Schoolcraft, Kathleen, Tsai, Jessica, Wang, Dayle, Jones, Robert, Vogelzang, Jayne, Pelton, Kristine, Becker, Sarah, Watkinson, Fiona, Sinai, Claire, Cohen, Elizabeth F, Booker, Matthew A, Tolstorukov, Michael Y, Haemels, Veerle, Goumnerova, Liliana, Wright, Karen, Kieran, Mark, Fehnel, Katie, Reardon, David, Tauziede-Espariat, Arnault, Lulla, Rishi, Carcamo, Benjamin, Chaleff, Stanley, Charest, Alain, De Smet, Frederik, Ligon, Azra H, Dubuc, Adrian, Pages, Melanie, Varlet, Pascale, Wen, Patrick Y, Alexander, Brian M, Chi, Susan, Alexandrescu, Sanda, Kittler, Ralf, Bachoo, Robert, Bandopadhayay, Pratiti, Beroukhim, Rameen, Ligon, Keith L

“…Anaplastic lymphoma kinase (ALK) aberrations have been identified in pediatric-type infant gliomas, but their occurrence across age groups, functional effects,…”
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Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma by Bandopadhayay, Pratiti, Piccioni, Federica, O’Rourke, Ryan, Ho, Patricia, Gonzalez, Elizabeth M., Buchan, Graham, Qian, Kenin, Gionet, Gabrielle, Girard, Emily, Coxon, Margo, Rees, Matthew G., Brenan, Lisa, Dubois, Frank, Shapira, Ofer, Greenwald, Noah F., Pages, Melanie, Balboni Iniguez, Amanda, Paolella, Brenton R., Meng, Alice, Sinai, Claire, Roti, Giovanni, Dharia, Neekesh V., Creech, Amanda, Tanenbaum, Benjamin, Khadka, Prasidda, Tracy, Adam, Tiv, Hong L., Hong, Andrew L., Coy, Shannon, Rashid, Rumana, Lin, Jia-Ren, Cowley, Glenn S., Lam, Fred C., Goodale, Amy, Lee, Yenarae, Schoolcraft, Kathleen, Vazquez, Francisca, Hahn, William C., Tsherniak, Aviad, Bradner, James E., Yaffe, Michael B., Milde, Till, Pfister, Stefan M., Qi, Jun, Schenone, Monica, Carr, Steven A., Ligon, Keith L., Kieran, Mark W., Santagata, Sandro, Olson, James M., Gokhale, Prafulla C., Jaffe, Jacob D., Root, David E., Stegmaier, Kimberly, Johannessen, Cory M., Beroukhim, Rameen

“…BET-bromodomain inhibition (BETi) has shown pre-clinical promise for MYC-amplified medulloblastoma. However, the mechanisms for its action, and ultimately for…”
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DIPG-53. CHARACTERIZING THE ROLE OF PPM1D MUTATIONS IN THE PATHOGENESIS OF DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPGS) by Khadka, Prasidda, Reitman, Zachary, Lu, Sophie, Buchan, Graham, Hartley, Rachel, Bear, Heather, Georgis, Yoahnna, Jarmale, Spandana, Schoolcraft, Kathleen, Miller, Peter, Gonzalez, Elizabeth, Gionet, Gabrielle, Qian, Kenin, Melanson, Randy, Keshishian, Hasmik, Carvalho, Diana, Condurat, Alexandra, Goodale, Amy, Abid, Tanaz, Piccioni, Federica, Chi, Susan, Carr, Steven, Haas-Kogan, Daphne, Ebert, Benjamin, Kieran, Mark, Jones, Chris, Ligon, Keith, Beroukhim, Rameen, Phoenix, Timothy, Bandopadhayay, Pratiti

“…Abstract INTRODUCTION We have previously found that up to 15% of all DIPGs harbor mutations in PPM1D, resulting in the expression of an activated and truncated…”
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DIPG-12. CHARACTERIZING THE ROLE OF PPM1D MUTATIONS IN THE PATHOGENESIS OF DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPGs) by Khadka, Prasidda, Reitman, Zachary J, Buchan, Graham, Hartley, Rachel, Bear, Heather, Georgis, Yohanna, Jarmale, Spandana, Schoolcraft, Kathleen, Miller, Peter, Stiles, Charles D, Chowdhury, Dipanjan, Haas-Kogan, Daphne, Johannessen, Cory, Ebert, Benjamin L, Ligon, Keith L, Phoenix, Timothy, Beroukhim, Rameen, Bandopadhayay, Pratiti

“…Abstract Diffuse Intrinsic Pontine Gliomas (DIPGs) are universally fatal. Effective treatments are desperately needed. DIPGs harbor histone K27M mutations…”
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PDTM-06. ALK AMPLIFICATION AND REARRANGEMENTS ARE RECURRENT TARGETABLE EVENTS IN GLIOBLASTOMA by Blandin, Anne-Florence, Graham, Maya, Ramkissoon, Shakti, Ramkissoon, Lori, Pelton, Kristine, Pages, Mélanie, Jones, Robert, Becker, Sarah, Watkinson, Fiona, Schoolcraft, Kathleen, Haemels, Veerle, Goumnerova, Liliana, Chi, Susan, Wright, Karen, Kieran, Mark, Tauziede-espariat, Arnault, Varlet, Pascale, Alexandrescu, Sanda, Reardon, David, Carcamo, Benjamin, Charest, Al, De Smet, Frederik, Beroukhim, Rameen, Dubuc, Adrian, Kittler, Ralf, Wen, Patrick, Alexander, Brian, Bandopadhayay, Pratiti, Bachoo, Robert, Ligon, Keith

“…Abstract Anaplastic Lymphoma Kinase (ALK) expression, rearrangements, and single nucleotide variants have been reported in several brain tumor types, but the…”
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