Search Results - "Schonbrunn, A."

Somatostatin receptors present knowledge and future directions by SCHONBRUNN, A

“…Genes for five somatostatin receptor subtypes, designated sst1–5, have been cloned and shown to belong to the seven transmembrane domain receptor family. The…”
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Distinct phosphorylation sites in the SST2A somatostatin receptor control internalization, desensitization, and arrestin binding by Liu, Q, Dewi, D A, Liu, W, Bee, M S, Schonbrunn, A

“…The somatostatin subtype 2A (sst2A) receptor, a member of the G protein-coupled receptor superfamily, mediates many of the neuroendocrine and neuromodulatory…”
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Classification and nomenclature of somatostatin receptors by Hoyer, D., Bell, G.I., Berelowitz, M., Epelbaum, J., Feniuk, W., Humphrey, P.P.A., O'Carroll, A-M., Patel, Y.C., Schonbrunn, A., Taylor, J.E., Reisine, T.

“…There is considerable controversy about the classification and nomenclature of somatostatin receptors. To date, five distinct receptor genes have been cloned…”
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Cellular detection of sst2A receptors in human gastrointestinal tissue by Gugger, M, Waser, B, Kappeler, A, Schonbrunn, A, Reubi, J C

“…Background and aim: Many neuroendocrine gastrointestinal tumours express receptors for the regulatory peptide somatostatin. Among the five existing…”
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Immunohistochemical Detection of Somatostatin Receptor Subtypes sst1 and sst2A in Human Somatostatin Receptor Positive Tumors by Hofland, L.J, Liu, Q, van Koetsveld, P.M, Zuijderwijk, J, van der Ham, F, de Krijger, R.R, Schonbrunn, A, Lamberts, S.W.J

“…Although in situ hybridization has been used to examine the distribution of messenger RNA for somatostatin receptor subtypes (sst) in human tumors, the…”
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Immunohistochemical Localization of Somatostatin Receptors sst2A in Human Tumors by Reubi, Jean Claude, Kappeler, Andreas, Waser, Beatrice, Laissue, Jean, Hipkin, R. William, Schonbrunn, Agnes

“…Human tumors frequently express somatostatin receptors. However, none of the receptor subtype proteins have been individually visualized in normal or…”
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Potassium channel stimulation by natriuretic peptides through cGMP-dependent dephosphorylation by White, R. E, Lee, A. B, Shcherbatko, A. D, Lincoln, T. M, Schonbrunn, A, Armstrong, D. L

“…Natriuretic peptides inhibit the release and action of many hormones through cyclic guanosine monophosphate (cGMP), but the mechanism of cGMP action is…”
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Antigen-specific expansion of human regulatory T cells as a major tolerance mechanism against mucosal fungi by Bacher, P, Kniemeyer, O, Schönbrunn, A, Sawitzki, B, Assenmacher, M, Rietschel, E, Steinbach, A, Cornely, O A, Brakhage, A A, Thiel, A, Scheffold, A

“…Foxp3 + regulatory T cells (Treg) have a central role for keeping the balance between pro- and anti-inflammatory immune responses against chronically…”
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Immunohistochemical Localization of Somatostatin Receptor sst2A in Human Pancreatic Islets by Reubi, J. C, Kappeler, A, Waser, B, Schonbrunn, A, Laissue, J

“…Somatostatin and octreotide inhibit endocrine pancreatic functions in man, via specific somatostatin receptors. However, the cellular distribution of the…”
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Immunohistochemical Localization of Somatostatin Receptor sst2A in Human Gut and Lung Tissue: Possible Implications for Physiology and Carcinogenesis by Gugger, M, Waser, B, Kappeler, A, Schonbrunn, A, Reubi, JC

“…: Many neuroendocrine gastrointestinal and lung tumors express sst2A somatostatin receptors. Because the cellular location of sst2A in the corresponding…”
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Somatostatin receptor subtypes in human thymoma and inhibition of cell proliferation by octreotide in vitro by FERONE, D, VAN HAGEN, M. P, KWEKKEBOOM, D. J, VAN KOETSVELD, P. M, MOOY, D. M, LICHTENAUER-KALIGIS, E, SCHÖNBRUNN, A, COLAO, A, LAMBERTS, S. W. J, HOFLAND, L. J

“…Somatostatin (SS) and SS receptor (SSR) subtypes, code-named sst1-5, are heterogeneously expressed in the normal human thymus. This suggests their involvement…”
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Pituitary Somatostatin Receptor (sst)1–5 Expression during Rat Development: Age-Dependent Expression of sst2 by Reed, D K, Korytko, A I, Hipkin, R W, Wehrenberg, W B, Schonbrunn, A, Cuttler, L

“…The capacity of the pituitary to suppress hormone secretion in response to somatostatin (SRIF) is markedly age dependent. Immature pituitaries are relatively…”
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Affinity purification of a somatostatin receptor-G-protein complex demonstrates specificity in receptor-G-protein coupling by BROWN, P. J, SCHONBRUNN, A

“…The inhibitory neuropeptide somatostatin (SRIF) initiates many of its physiological effects by binding to membrane receptors which are coupled to pertussis…”
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The bombesin receptor is coupled to a guanine nucleotide-binding protein which is insensitive to pertussis and cholera toxins by Fischer, J B, Schonbrunn, A

“…The neuropeptide bombesin acts on a variety of target cells to stimulate the processes of secretion and cell proliferation. In this study we determined whether…”
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Receptor-mediated internalization of somatostatin in rat cortical and hippocampal neurons by Stroh, T., Jackson, A.C., Dal Farra, C., Schonbrunn, A., Vincent, J.P., Beaudet, A.

“…Binding of neuropeptides to their receptors usually results in internalization of receptor‐ligand complexes. This process serves a crucial role in receptor…”
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Somatostatin pretreatment increases the number of somatostatin receptors in GH4C1 pituitary cells and does not reduce cellular responsiveness to somatostatin by Presky, D H, Schonbrunn, A

“…The GH4C1 pituitary cell line contains specific plasma membrane receptors for the inhibitory neuropeptide somatostatin (SRIF). Unlike other peptides which bind…”
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Characterization of functional receptors for somatostatin in rat pituitary cells in culture by A Schonbrunn, H Tashjian, Jr

“…GH4C1 cells are a clonal strain of rat pituitary tumor cells which synthesize and secrete prolactin and growth hormone. Somatostatin, a hypothalamic…”
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Characterization of the cyclic AMP-independent actions of somatostatin in GH cells. II. An increase in potassium conductance initiates somatostatin-induced inhibition of prolactin secretion by Koch, B D, Schonbrunn, A

“…The neuropeptide somatostatin inhibits prolactin release from GH4C1 pituitary cells via two mechanisms, inhibition of stimulated adenylate cyclase activity and…”
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Characterization of bombesin receptors in a rat pituitary cell line by Westendorf, J M, Schonbrunn, A

“…Bombesin is a tetradecapeptide which stimulates prolactin secretion in rats and man and in cultures of GH4C1 cells, a clonal strain of rat pituitary tumor…”
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Pertussis toxin blocks both cyclic AMP-mediated and cyclic AMP-independent actions of somatostatin. Evidence for coupling of Ni to decreases in intracellular free calcium by Koch, B D, Dorflinger, L J, Schonbrunn, A

“…The neuropeptide somatostatin inhibits hormone release from GH4C1 pituitary cells via two mechanisms: inhibition of stimulated adenylate cyclase and a…”
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