Search Results - "Scholz, Peter M"

Diabetes mellitus increases short-term mortality and morbidity in patients undergoing coronary artery bypass graft surgery by Carson, Jeffrey L., Scholz, Peter M., Chen, Anita Y., Peterson, Eric D., Gold, Jeffrey, Schneider, Stephen H.

“…The aim of this study was to determine the impact of diabetes mellitus (DM) on short-term mortality and morbidity in patients undergoing coronary artery bypass…”
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Role of Phospholamban in Cyclic GMP Mediated Signaling in Cardiac Myocytes by Zhang, Qihang, Scholz, Peter M., Pilzak, Anna, Su, Jun, Weiss, Harvey R.

“…We tested the hypothesis that the negative functional effects of cyclic GMP on cardiac myocytes were mediated through phospholamban (PLB) and activation of…”
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Functional effects of C-type natriuretic peptide and nitric oxide are attenuated in hypertrophic myocytes from pressure-overloaded mouse hearts by Su, Jun, Zhang, Qihang, Moalem, Jacob, Tse, James, Scholz, Peter M, Weiss, Harvey R

“…Increases in the myocardial level of cGMP usually exert negative inotropic effects in the mammalian hearts. We tested the hypothesis that the negative…”
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PROSE: Prospective Randomized Trial of the On-X Mechanical Prosthesis and the St Jude Medical Mechanical Prosthesis Evaluation: Part 1(Patient Dynamics): Preoperative demographics and preoperative and operative risk factors by Jamieson, W. R. Eric, Ely, John L., Brink, Johan, Pennel, Timothy, Bannon, Paul, Patel, Jashvant, Kumar Gupta, Rajiv, Mohan Rao, Prasanna Simha, Agrawal, Damyanti, Wiklund, Lars, Kappetein, A. Pieter, Haaverstad, Rune, Geisner, Thomas, Doenst, Torsten, Schlensak, Christian, Nair, Salgunan, Brown, Craig, Siepe, Matthias, Damiano, Ralph J., Langlois, Yves, Cherian, K. M., Azar, Hormoz, Chen, John C., Bavaria, Joseph E., Fedoruk, Lynn M., Munfakh, Nabil A., Sridhar, V., Scholz, Peter M., Pfeffer, Thomas A., Ye, Jian

“…Abstract Objectives The PROSE trial purpose is to investigate whether the incidence of thromboembolic—related complications is reduced with a current…”
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PROSE: Prospective Randomized Trial of the On-X Mechanical Prosthesis and the St Jude Medical Mechanical Prosthesis Evaluation: Part 2: Study results-prostheses, positions, and economic development by Jamieson, W R Eric, Ely, John L, Brink, Johan, Pennel, Timothy, Bannon, Paul, Patel, Jashvant, Gupta, Rajiv Kumar, Mohan Rao, Prasanna Simha, Agrawal, Damyanti, Wiklund, Lars, Kappetein, A Pieter, Haaverstad, Rune, Geisner, Thomas, Doenst, Torsten, Schlensak, Christian, Nair, Salgunan, Brown, Craig, Siepe, Matthias, Damiano, Ralph J, Langlois, Yves, Cherian, Kotturathu M, Azar, Hormoz, Chen, John C, Bavaria, Joseph E, Fedoruk, Lynn M, Munfakh, Nabil A, Sridhar, V, Scholz, Peter M, Pfeffer, Thomas A, Ye, Jian

“…The Prospective Randomized On-X Mechanical Prosthesis Versus St Jude Medical Mechanical Prosthesis Evaluation (PROSE) trial purpose was to investigate whether…”
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PROSE: Prospective Randomized Trial of the On-X Mechanical Prosthesis and the St Jude Medical Mechanical Prosthesis Evaluation by Jamieson, W. R. Eric, Ely, John L, Brink, Johan, Pennel, Timothy, Bannon, Paul, Patel, Jashvant, Kumar Gupta, Rajiv, Mohan Rao, Prasanna Simha, Agrawal, Damyanti, Wiklund, Lars, Kappetein, A. Pieter, Haaverstad, Rune, Geisner, Thomas, Doenst, Torsten, Schlensak, Christian, Nair, Salgunan, Brown, Craig, Siepe, Matthias, Damiano, Ralph J, Langlois, Yves, Cherian, K. M, Azar, Hormoz, Chen, John C, Bavaria, Joseph E, Fedoruk, Lynn M, Munfakh, Nabil A, Sridhar, V, Scholz, Peter M, Pfeffer, Thomas A, Ye, Jian

“…Objectives The PROSE trial purpose is to investigate whether the incidence of thromboembolic--related complications is reduced with a current generation…”
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Hypoxia inducible factor-1 improves the negative functional effects of natriuretic peptide and nitric oxide signaling in hypertrophic cardiac myocytes by Tan, Tao, Scholz, Peter M., Weiss, Harvey R.

“…Both natriuretic peptides and nitric oxide may be protective in cardiac hypertrophy, although their functional effects are diminished in hypertrophy. Hypoxia…”
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Differential effects of cGMP produced by soluble and particulate guanylyl cyclase on mouse ventricular myocytes by Su, Jun, Scholz, Peter M, Weiss, Harvey R

“…Particulate guanylyl cyclase (pGC) and soluble guanylyl cyclase (sGC) are cGMP-generation systems distributed in different intracellular locations. Our aim was…”
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HYPOXIA-INDUCIBLE FACTOR-1 IMPROVES THE ACTIONS OF POSITIVE INOTROPIC AGENTS IN STUNNED CARDIAC MYOCYTES by Tan, Tao, Luciano, Jason A, Scholz, Peter M, Weiss, Harvey R

“…SUMMARY 1 In the present study, we tested hypothesis that upregulation of hypoxia‐inducible factor‐1 (HIF‐1) would improve the actions of positive inotropic…”
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Effects of natriuretic peptides on ventricular myocyte contraction and role of cyclic GMP signaling by Zhang, Qihang, Moalem, Jacob, Tse, James, Scholz, Peter M., Weiss, Harvey R.

“…Natriuretic peptides, including atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP) and C-type natriuretic peptide (CNP) act through different…”
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SERCA inhibition limits the functional effects of cyclic GMP in both control and hypertrophic cardiac myocytes by Zhang, Qihang, Davidov, Tomer, Weiss, Harvey R, Scholz, Peter M

“…The negative functional effects of cyclic GMP are controlled by the sarcoplasmic reticulum calcium-ATPase (SERCA). The effects of cyclic GMP are blunted in…”
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Chronic nitric oxide synthase blockade desensitizes the heart to the negative metabolic effects of nitric oxide by Davidov, Tomer, Weiss, Harvey R., Tse, James, Scholz, Peter M.

“…The consequences of chronic nitric oxide synthase (NOS) blockade on the myocardial metabolic and guanylyl cyclase stimulatory effects of exogenous nitric oxide…”
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Negative Functional Effects of Natriuretic Peptides Are Attenuated in Hypertrophic Cardiac Myocytes by Reduced Particulate Guanylyl Cyclase Activity by Meyer, Mark, Zhang, Qihang, Khurana, Kiranpreet, Scholz, Peter M, Weiss, Harvey R

“…We tested the hypothesis that the negative functional effects of natriuretic peptides would be blunted in thyroxine (T4)-induced hypertrophic cardiac myocytes…”
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T4-induced cardiac hypertrophy disrupts cyclic GMP mediated responses to brain natriuretic peptide in rabbit myocardium by Katz, Elizabeth, Zhang, Qihang, Weiss, Harvey R., Scholz, Peter M.

“…Brain natriuretic peptide (BNP) affects the regulation of myocardial metabolism through the production of cGMP and these effects may be altered by cardiac…”
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Aging Blunts the Effect of Nitric Oxide on Myocardial O2 Consumption by Weiss, Harvey R, Lazar, Michael J, Tse, James, Scholz, Peter M

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Importance of ryanodine receptors in effects of cyclic GMP is reduced in thyroxine-induced cardiac hypertrophy by Zhang, Qihang, Goel, Nishant, Rodriguez, Roberto, Scholz, Peter M., Weiss, Harvey R.

“…We tested the hypothesis that the negative functional effects of cyclic GMP were mediated by ryanodine receptors, and that these effects would be reduced in…”
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Chronic nitrates blunt the effects of not only nitric oxide but also natriuretic peptides in cardiac myocytes by Tan, Tao, Zhang, Qihang, Anyadike, Chukwuma, Scholz, Peter M., Weiss, Harvey R.

“…Exposure to nitrates causes tachyphylaxis to nitric oxide (NO), which reduces the effects of the second messenger cyclic guanosine-3′,-5′-monophosphate (cyclic…”
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Cyclic GMP signaling and regulation of SERCA activity during cardiac myocyte contraction by Zhang, Qihang, Scholz, Peter M., He, Yiqi, Tse, James, Weiss, Harvey R.

“…We tested the hypothesis that cGMP-induced reductions in cardiac myocyte function were related to activation of the sarcoplasmic reticulum Ca 2+-ATPase (SERCA)…”
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Heart Failure Reduces Both the Effects and Interaction Between Cyclic GMP and Cyclic AMP by Moalem, Jacob, Weiss, Harvey R., Davidov, Tomer, Rodriguez, Roberto, Molino, Bruno, Lazar, Michael J., Scholz, Peter M.

“…We tested the hypothesis that the negative functional effects of cyclic GMP would be attenuated by cyclic AMP and this interaction would be reduced in…”
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Negative Inotropic Effects of C-Type Natriuretic Peptide are Attenuated in Hypertrophied Ventricular Myocytes Associated with Reduced Cyclic GMP Production by Moalem, Jacob, Davidov, Tomer, Zhang, Qihang, Grover, Gary J., Weiss, Harvey R., Scholz, Peter M.

“…We tested the hypothesis that the negative inotropic effects of C-type natriuretic peptide (CNP) would be diminished in renal hypertensive…”
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