Search Results - "Scholpp, Joachim"

Neuroimaging Biomarkers for Drug Discovery and Development in Schizophrenia by Preller, Katrin H., Scholpp, Joachim, Wunder, Andreas, Rosenbrock, Holger

“…Schizophrenia is a chronic mental illness that affects up to 1% of the population. While efficacious therapies are available for positive symptoms, effective…”
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Sedation in the intensive care unit with remifentanil/propofol versus midazolam/fentanyl: a randomised, open-label, pharmacoeconomic trial by Muellejans, Bernd, Matthey, Thomas, Scholpp, Joachim, Schill, Markus

“…Remifentanil is an opioid with a unique pharmacokinetic profile. Its organ-independent elimination and short context-sensitive half time of 3 to 4 minutes lead…”
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Investigation of the predictive validity of laser‐EPs in normal, UVB‐inflamed and capsaicin‐irritated skin with four analgesic compounds in healthy volunteers by Schaffler, Klaus, Nicolas, Laurent B., Borta, Andreas, Brand, Tobias, Reitmeir, Peter, Roebling, Robert, Scholpp, Joachim

“…Aims The aim of the present study was to assess the predictivity of laser‐(radiant‐heat)‐evoked potentials (LEPs) from the vertex electroencephalogram, using…”
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P3‐282: Single oral doses of the novel bace inhibitor bi 1181181 significantly reduce concentrations of cerebrospinal fluid amyloid‐beta peptides in healthy subjects by Borta, Andreas, Nicolas, Laurent, Kleiner, Oliver, Kammerer, Klaus-Peter, Schaible, Jennifer, Pietzko, Kerstin, Podhorna, Jana, Dorner-Ciossek, Cornelia, Scholpp, Joachim

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P3‐283: Pharmacokinetics, pharmacodynamics, and safety of the novel bace inhibitor bi1181181 after oral administration of single ascending doses in healthy subjects by Nicolas, Laurent, Kammerer, Klaus-Peter, Schaible, Jennifer, Link, Jasmin, Kleiner, Oliver, Borta, Andreas, Podhorna, Jana, Scholpp, Joachim

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Pharmacokinetics, pharmacodynamics, and safety of the novel bace inhibitor bi1181181 after oral administration of single ascending doses in healthy subjects by Nicolas, Laurent, Kammerer, Klaus-Peter, Schaible, Jennifer, Link, Jasmin, Kleiner, Oliver, Borta, Andreas, Podhorna, Jana, Scholpp, Joachim

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Single oral doses of the novel bace inhibitor bi 1181181 significantly reduce concentrations of cerebrospinal fluid amyloid-beta peptides in healthy subjects by Borta, Andreas, Nicolas, Laurent, Kleiner, Oliver, Kammerer, Klaus-Peter, Schaible, Jennifer, Pietzko, Kerstin, Podhorna, Jana, Dorner-Ciossek, Cornelia, Scholpp, Joachim

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Early treatment of a migraine attack while pain is still mild increases the efficacy of sumatriptan by Scholpp, J, Schellenberg, R, Moeckesch, B, Banik, N

“…To investigate the hypothesis that early treatment of a migraine attack with sumatriptan, while pain is still mild, results in higher pain free rates in…”
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Breath markers and soluble lipid peroxidation markers in critically ill patients by Scholpp, Joachim, Schubert, Jochen K, Miekisch, Wolfram, Geiger, Klaus

“…Free radical-mediated inflammatory processes account for a great portion of morbidity and mortality in critically ill patients. The purpose of this study was…”
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A Thorough QT Study of Teduglutide in Healthy Subjects by Hartmann, Manfred, Timmer, Wolfgang, Schultz, Armin, Nave, Rüdiger, Luehmann, Reinhold, Krause, Stephan, Lahu, Gezim, Scholpp, Joachim

“…Teduglutide, an analog of the endogenous hormone glucagon‐like peptide‐2, is currently being developed for the treatment of short bowel syndrome. This study…”
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Lipid peroxidation early after brain injury by Scholpp, Joachim, Schubert, Jochen K, Miekisch, Wolfram, Noeldge-Schomburg, Gabriele F E

“…The role of lipid peroxidation after brain injury is still not completely understood, and results of different studies have been equivocal. In this study,…”
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Evaluation of markers of deep vein thrombosis in patients undergoing surgery for maxillofacial malignancies by Wendel, Hans P., Scholpp, Joachim, Schulze, Hans-Joachim, Heller, Wolfgang, Schwenzer, Norbert

“…During and following significant surgical intervention, deep venous thrombosis prophylaxis by application of anticoagulants is routinely used. However,…”
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