Search Results - "Scholl, Suzy"

Therapeutic vaccines for cancer: an overview of clinical trials by Melero, Ignacio, Gaudernack, Gustav, Gerritsen, Winald, Huber, Christoph, Parmiani, Giorgio, Scholl, Suzy, Thatcher, Nicholas, Wagstaff, John, Zielinski, Christoph, Faulkner, Ian, Mellstedt, Håkan

“…Key Points Development of vaccines for the treatment of cancer has posed many challenges, but results from some recent studies have confirmed the potential for…”
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Human papilloma virus (HPV) integration signature in Cervical Cancer: identification of MACROD2 gene as HPV hot spot integration site by Kamal, Maud, Lameiras, Sonia, Deloger, Marc, Morel, Adeline, Vacher, Sophie, Lecerf, Charlotte, Dupain, Célia, Jeannot, Emmanuelle, Girard, Elodie, Baulande, Sylvain, Dubot, Coraline, Kenter, Gemma, Jordanova, Ekaterina S., Berns, Els M. J. J., Bataillon, Guillaume, Popovic, Marina, Rouzier, Roman, Cacheux, Wulfran, Le Tourneau, Christophe, Nicolas, Alain, Servant, Nicolas, Scholl, Suzy M., Bièche, Ivan

“…Background Cervical cancer (CC) remains a leading cause of gynaecological cancer-related mortality with infection by human papilloma virus (HPV) being the most…”
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Systematic assessment of tumor necrosis at baseline in cervical cancer - An independent factor associated with poor outcome by Chouchane-Mlik, Olfa, Oniga, Alexandra, Latouche, Aurélien, Halladjian, Maral, Kleine-Borgmann, Felix B, Gérardy, Jean-Jacques, Mittelbronn, Michel, Kamal, Maud, Scholl, Suzy M

“…Cervical cancer (CC) is a leading challenge in oncology worldwide, with high prevalence and mortality rates in young adults, most prominent in low to…”
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HPV16 E7 DNA tattooing: safety, immunogenicity, and clinical response in patients with HPV-positive vulvar intraepithelial neoplasia by Samuels, Sanne, Marijne Heeren, A., Zijlmans, Henry J. M. A. A., Welters, Marij J. P., van den Berg, Joost H., Philips, Daisy, Kvistborg, Pia, Ehsan, Ilina, Scholl, Suzy M. E., Nuijen, Bastiaan, Schumacher, Ton N. M., van Beurden, Marc, Jordanova, Ekaterina S., Haanen, John B. A. G., van der Burg, Sjoerd H., Kenter, Gemma G.

“…Background Usual type vulvar intraepithelial neoplasia (uVIN) is caused by HPV, predominantly type 16. Several forms of HPV immunotherapy have been studied,…”
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High Numbers of Differentiated Effector CD4 T Cells Are Found in Patients with Cancer and Correlate with Clinical Response after Neoadjuvant Therapy of Breast Cancer by PEGUILLET, Isabelle, MILDER, Maud, LOUIS, Delphine, VINCENT-SALOMON, Anne, DORVAL, Thierry, PIPERNO-NEUMANN, Sophie, SCHOLL, Suzy M, LANTZ, Olivier

“…CD4(+) T cells influence tumor immunity in complex ways that are not fully understood. In this study, we characterized a population of human differentiated…”
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PIK3CA Pathway Mutations Predictive of Poor Response Following Standard Radiochemotherapy ± Cetuximab in Cervical Cancer Patients by de la Rochefordiere, Anne, Kamal, Maud, Floquet, Anne, Thomas, Laurence, Petrow, Peter, Petit, Thierry, Pop, Marius, Fabbro, Michel, Kerr, Christine, Joly, Florence, Sevin, Emmanuel, Maillard, Sophie, Curé, Hervé, Weber, Béatrice, Brunaud, Claire, Minsat, Mathieu, Gonzague, Laurence, Berton-Rigaud, Dominique, Aumont, Maud, Gladieff, Laurence, Peignaux, Karine, Bernard, Virginie, Leroy, Quentin, Bieche, Ivan, Margogne, Audrey, Nadan, AnaTereza, Fourchotte, Virginie, Diallo, Alhassane, Asselain, Benard, Plancher, Corine, Armanet, Sébastien, Beuzeboc, Philippe, Scholl, Suzy M

“…EGFR is frequently overexpressed in cervical cancer, suggesting EGFR blockade as a promising treatment approach. Cetuximab, an anti EGFR antibody, used…”
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Recommendations From an International Expert Panel on the Use of Neoadjuvant (Primary) Systemic Treatment of Operable Breast Cancer: An Update by Kaufmann, Manfred, Hortobagyi, Gabriel N, Goldhirsch, Aron, Scholl, Suzy, Makris, Andreas, Valagussa, Pinuccia, Blohmer, Jens-Uwe, Eiermann, Wolfgang, Jackesz, Raimund, Jonat, Walter, Lebeau, Annette, Loibl, Sibylle, Miller, William, Seeber, Sigfried, Semiglazov, Vladimir, Smith, Roy, Souchon, Rainer, Stearns, Vered, Untch, Michael, von Minckwitz, Gunter

“…Neoadjuvant (primary systemic) treatment is the standard treatment for locally advanced breast cancer and a standard option for primary operable disease…”
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RAIDS atlas of significant genetic and protein biomarkers in cervical cancer by Scholl, Suzy, Roufai, Diana Bello, Chérif, Linda Larbi, Kamal, Maud

“…Loss of function in epigenetic acting genes together with driver alterations in the PIK3CA pathway have been shown significantly associated with poor outcome…”
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Regression of high-grade cervical intraepithelial neoplasia with TG4001 targeted immunotherapy by Brun, Jean-Luc, MD, Dalstein, Véronique, PhD, Leveque, Jean, MD, PhD, Mathevet, Patrice, MD, PhD, Raulic, Patrick, MD, Baldauf, Jean-Jacques, MD, Scholl, Suzy, MD, Huynh, Bernard, MD, Douvier, Serge, MD, PhD, Riethmuller, Didier, MD, PhD, Clavel, Christine, PhD, Birembaut, Philippe, MD, PhD, Calenda, Valérie, PhD, Baudin, Martine, MD, PhD, Bory, Jean-Paul, MD

“…Objective We sought to evaluate the safety and efficacy of TG4001 in patients with human papillomavirus (HPV) 16–related cervical intraepithelial neoplasia…”
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Genetic markers and phosphoprotein forms of beta-catenin pβ-Cat552 and pβ-Cat675 are prognostic biomarkers of cervical cancer by Scholl, Suzy M, Beal, Jonas, de Koning, Leanne, Girard, Elodie, Popovic, Marina, de la Rochefordière, Anne, Lecuru, Fabrice, Fourchotte, Virginie, Ngo, Charlotte, Floquet, Anne, Berns, Els MJJ, Kenter, Gemma, Gestraud, Pierre, von der Leyen, Heiko, Lecerf, Charlotte, Puard, Vincent, Roman, Sergio Roman, Latouche, Aurelien, Kereszt, Attila, Balint, Balazs, Rouzier, Roman, Kamal, Maud

“…Cervical cancer (CC) remains a leading cause of gynaecological cancer-related mortality world wide and constitutes the third most common malignancy in women…”
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Advances and Concepts in Cervical Cancer Trials: A Road Map for the Future by Sagae, Satoru, Monk, Bradley J, Pujade-Lauraine, Eric, Gaffney, David K, Narayan, Kailash, Ryu, Sang Young, McCormack, Mary, Plante, Marie, Casado, Antonio, Reuss, Alexander, Chávez-Blanco, Adriana, Kitchener, Henry, Nam, Byung-Ho, Jhingran, Anuja, Temkin, Sarah, Mileshkin, Linda, Berns, Els, Scholl, Suzy, Doll, Corinne, Abu-Rustum, Nadeem R, Lecuru, Fabrice, Small, Jr, William

“…Cervical cancer is responsible for more than a quarter of a million deaths globally each year, mostly in developing countries, making therapeutic advances in…”
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Characterization of Breast Cancer Preclinical Models Reveals a Specific Pattern of Macrophage Polarization by Vallerand, David, Massonnet, Gérald, Kébir, Fatima, Gentien, David, Maciorowski, Zofia, De la Grange, Pierre, Sigal-Zafrani, Brigitte, Richardson, Marion, Humbert, Sandrine, Thuleau, Aurélie, Assayag, Franck, de Plater, Ludmilla, Nicolas, André, Scholl, Suzy, Marangoni, Elisabetta, Weigand, Stefan, Roman-Roman, Sergio, Savina, Ariel, Decaudin, Didier

“…Drug discovery efforts have focused on the tumor microenvironment in recent years. However, few studies have characterized the stroma component in…”
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Corrigendum to ‘clinical and genetic landscape of treatment naive cervical cancer: Alterations in PIK3CA and in epigenetic modulators associated with sub-optimal outcome’ by Scholl, Suzy, Popovic, Marina, Rochefordiere, Anne de la, Girard, Elodie, Dureau, Sylvain, Mandic, Aljosa, Koprivsek, Katarina, Samet, Nina, Craina, Marius, Margan, Madalin, Samuels, Sanne, Zijlmans, Henry, Kenter, Gemma, Hillemanns, Peter, Dema, Sorin, Dema, Alis, Malenkovic, Goran, Djuran, Branislav, Floquet, Anne, Garbay, Delphine, Guyon, Frédéric, Colombo, Pierre Emmanuel, Fabbro, Michel, Kerr, Christine, Ngo, Charlotte, Lecuru, Fabrice, del Campo, Eleonor Rivin, Coutant, Charles, Marchal, Frédéric, Mesgouez-Nebout, Nathalie, Fourchotte, Virginie, Feron, Jean Guillaume, Morice, Philippe, Deutsch, Eric, Wimberger, Pauline, Classe, Jean-Marc, Gleeson, Noreen, Leyen, Heiko von der, Minsat, Mathieu, Dubot, Coraline, Gestraud, Pierre, Kereszt, Attila, Nagy, Istvan, Balint, Balazs, Berns, Els, Jordanova, Ekaterina, de Saint-Jorre, Nicolas, Savignoni, Alexia, Servant, Nicolas, Hupe, Philippe, de Koning, Leanne, Fumoleau, Pierre, Rouzier, Roman, Kamal, Maud

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Gynecological Cancers Translational, Research Implementation, and Harmonization: Gynecologic Cancer InterGroup Consensus and Still Open Questions by Bagnoli, Marina, Shi, Ting Yan, Gourley, Charlie, Speiser, Paul, Reuss, Alexander, Nijman, Hans W, Creutzberg, Carien L, Scholl, Suzy, Negrouk, Anastassia, Brady, Mark F, Hasegawa, Kosei, Oda, Katsutoshi, McNeish, Iain A, Kohn, Elise C, Oza, Amit M, MacKay, Helen, Millan, David, Bennett, Katherine, Scott, Clare, Mezzanzanica, Delia

“…In the era of personalized medicine, the introduction of translational studies in clinical trials has substantially increased their costs, but provides the…”
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Fundamental Principles of Raising an Antitumour Immune Response in Vivo: A Complex Model, a Case Report, and a Perspective by Scholl, Suzy M.

“…In preclinical model systems, the fundamental principles underlying a successful and durable anti-tumour immune response are well demonstrated. In clinical…”
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Circulating HPV DNA as a Marker for Early Detection of Relapse in Patients with Cervical Cancer by Jeannot, Emmanuelle, Latouche, Aurélien, Bonneau, Claire, Calméjane, Marie-Ange, Beaufort, Corine, Ruigrok-Ritstier, Kirsten, Bataillon, Guillaume, Larbi Chérif, Linda, Dupain, Célia, Lecerf, Charlotte, Popovic, Marina, de la Rochefordière, Anne, Lecuru, Fabrice, Fourchotte, Virginie, Jordanova, Ekaterina S, von der Leyen, Heiko, Tran-Perennou, Carine, Legrier, Marie-Emmanuelle, Dureau, Sylvain, Raizonville, Laurence, Bello Roufai, Diana, Le Tourneau, Christophe, Bièche, Ivan, Rouzier, Roman, Berns, Els M J J, Kamal, Maud, Scholl, Suzy

“…Almost all cervical cancers are caused by human papillomavirus (HPV) and patients with advanced stage are at high risk for relapse. Circulating HPV DNA (HPV…”
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Outcome in Advanced Ovarian Cancer following an Appropriate and Comprehensive Effort at Upfront Cytoreduction: A Twenty-Year Experience in a Single Cancer Institute by De Margerie, Vincent, Dorval, Thierry, De La Rochefordière, Anne, Cottu, Paul, Petrow, Peter, Sastre-Garrau, Xavier, Salmon, Rémy Jacques, Marszalek, Anne, Meyniel, Jean Philippe, Rosty, Christophe, Plancher, Corinne, Alran, Séverine, Scholl, Susy M. E., Fourchotte, Virginie

“…Objectives. The purpose of this retrospective evaluation of advanced-stage ovarian cancer patients was to compare outcome with published findings from other…”
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Methylation, Gene Expression, and Risk Genotypes at the TERT-CLPTM1L Locus in Cervical Cancer by Ramachandran, Dhanya, Mao, Qianqian, Liao, Dandan, Kamal, Maud, Schürmann, Peter, Eisenblätter, Rieke, Geffers, Robert, Balint, Balazs, Lecompte, Lolita, Servant, Nicolas, Chérif, Linda Larbi, Lamy, Constance, Baulande, Sylvain, Legoix, Patricia, Le Tourneau, Christophe, Latouche, Aurélien, Hillemanns, Peter, Scholl, Suzy, Dörk, Thilo

“…The reverse transcriptase subunit of telomerase, TERT, is frequently activated in high-grade dysplasia and invasive cancers of the uterine cervix. Telomerase…”
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Simultaneous bilateral breast carcinomas: a retrospective review of 149 cases by de la Rochefordiere, A, Asselain, B, Scholl, S, Campana, F, Ucla, L, Vilcoq, J R, Durand, J C, Pouillart, P, Fourquet, A

“…To evaluate clinical and biological characteristics as well as treatment outcome in simultaneous bilateral breast carcinomas. Between 1981 and 1990, 149…”
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Prevention of Bone Metastases in Breast Cancer Patients. Therapeutic Perspectives by Beuzeboc, Philippe, Scholl, Suzy

“…One in four breast cancer patients is at risk of developing bone metastases in her life time. The early prevention of bone metastases is a crucial challenge…”
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