Search Results - "Scholey, J. M"
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Model for Anaphase B: Role of Three Mitotic Motors in a Switch from Poleward Flux to Spindle Elongation
Published in Proceedings of the National Academy of Sciences - PNAS (09-11-2004)“…It has been proposed that the suppression of poleward flux within interpolar microtubule (ipMT) bundles of Drosophila embryonic spindles couples outward forces…”
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Efficient Chromosome Capture Requires a Bias in the ‘Search-and-Capture’ Process during Mitotic-Spindle Assembly
Published in Current biology (10-05-2005)“…The mitotic spindle assembles into a bipolar, microtubule-based protein machine during prometaphase. One proposed mechanism for this process is…”
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Microtubule motors in mitosis
Published in Nature (London) (07-09-2000)“…The mitotic spindle uses microtubule-based motor proteins to assemble itself and to segregate sister chromatids. It is becoming clear that motors invoke…”
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Early spindle assembly in Drosophila embryos: role of a force balance involving cytoskeletal dynamics and nuclear mechanics
Published in Molecular biology of the cell (01-10-2005)“…Mitotic spindle morphogenesis depends upon the action of microtubules (MTs), motors and the cell cortex. Previously, we proposed that cortical- and MT-based…”
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A bipolar kinesin
Published in Nature (London) (18-01-1996)“…Chromosome segregation during mitosis depends on the action of the mitotic spindle, a self-organizing, bipolar protein machine which uses microtubules (MTs)…”
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A Force Balance Model of Early Spindle Pole Separation in Drosophila Embryos
Published in Biophysical journal (01-02-2003)“…The formation and function of the mitotic spindle depends upon force generation by multiple molecular motors and by the dynamics of microtubules, but how these…”
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The PKD protein qilin undergoes intraflagellar transport
Published in Current biology (07-06-2005)Get full text
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Movement of motor and cargo along cilia
Published in Nature (London) (22-04-1999)“…Intraflagellar transport (IFT) is important in the formation and maintenance of many cilia, such as the motile cilia that drive the swimming of cells and…”
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Model of Chromosome Motility in Drosophila Embryos: Adaptation of a General Mechanism for Rapid Mitosis
Published in Biophysical journal (01-06-2006)“…During mitosis, ensembles of dynamic MTs and motors exert forces that coordinate chromosome segregation. Typically, chromosomes align at the metaphase spindle…”
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Intraflagellar transport motors in Caenorhabditis elegans neurons
Published in Biochemical Society transactions (01-11-2004)“…IFT (intraflagellar transport) assembles and maintains sensory cilia on the dendritic endings of chemosensory neurons within the nematode Caenorhabditis…”
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The bimC family of kinesins: essential bipolar mitotic motors driving centrosome separation
Published in BBA - Molecular Cell Research (24-07-1997)Get full text
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The carboxyl-terminal domain of kinesin heavy chain is important for membrane binding
Published in The Journal of biological chemistry (14-01-1994)“…Sea urchin kinesin is a plus end-directed microtubule-based motor consisting of two heavy chains and two light chains and is proposed to be responsible (a) for…”
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Publication bias: raising awareness of a potential problem in dental research
Published in British dental journal (08-03-2003)“…With the development of evidence-based dentistry it is important to consider how accurate and representative our published pool of evidence is. In this article…”
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Inhibition of Kinesin-Driven Microtubule Motility by Monoclonal Antibodies to Kinesin Heavy Chains
Published in The Journal of cell biology (01-12-1988)“…We have prepared and characterized seven mouse monoclonal antibodies (SUK 1-7) to the 130-kD heavy chain of sea urchin egg kinesin. On immunoblots, SUK 3 and…”
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15
Cell division
Published in Nature (London) (17-04-2003)“…In creating the mitotic spindle and the contractile ring, natural selection has engineered fascinating precision machines whose movements depend upon forces…”
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A 'slow' homotetrameric kinesin-related motor protein purified from Drosophila embryos
Published in The Journal of biological chemistry (16-09-1994)“…Pan-kinesin peptide antibodies (Cole, D. G., Cande, W. Z., Baskin, R. J., Skoufias, D. A., Hogan, C. J., and Scholey, J.M. (1992) J. Cell Sci. 101, 291-301;…”
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Sequence and Submolecular Localization of the 115-kD Accessory Subunit of the Heterotrimeric Kinesin-II (KRP85/95) Complex
Published in The Journal of cell biology (01-02-1996)“…The heterotrimeric kinesin-II holoenzyme purified from sea urchin (Strongylocentrotus purpuratus) eggs is assembled from two heterodimerized kinesin-related…”
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An essential bipolar mitotic motor
Published in Nature (London) (21-11-1996)“…Separation of the mitotic spindle at the poles during cell division depends on the action of members of the bimC family of proteins. These proteins are part of…”
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Identification of kinesin in sea urchin eggs, and evidence for its localization in the mitotic spindle
Published in Nature (London) (01-12-1985)“…To understand the molecular basis of microtubule-associated motility during mitosis, the mechanochemical factors that generate the relevant motile force must…”
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Identification of a microtubule-based cytoplasmic motor in the nematode C. elegans
Published in Cell (23-10-1987)“…C. elegans contains a microtubule binding protein that resembles both dynein and kinesin. This protein has a MgATPase activity and copurifies on both sucrose…”
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