Search Results - "Scholes, Charles P"
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Porphyrin–phospholipid liposomes permeabilized by near-infrared light
Published in Nature communications (03-04-2014)“…The delivery of therapeutic compounds to target tissues is a central challenge in treating disease. Externally controlled drug release systems hold potential…”
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2
EPR–ENDOR Characterization of (17O, 1H, 2H) Water in Manganese Catalase and Its Relevance to the Oxygen-Evolving Complex of Photosystem II
Published in Journal of the American Chemical Society (25-01-2012)“…The synthesis of efficient water-oxidation catalysts demands insight into the only known, naturally occurring water-oxidation catalyst, the oxygen-evolving…”
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3
Spectroscopic and Computational Studies of Nitrite Reductase: Proton Induced Electron Transfer and Backbonding Contributions to Reactivity
Published in Journal of the American Chemical Society (14-01-2009)“…A combination of spectroscopy and DFT calculations has been used to define the geometric and electronic structure of the nitrite bound type 2 (T2) copper site…”
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4
Thermodynamic equilibrium between blue and green copper sites and the role of the protein in controlling function
Published in Proceedings of the National Academy of Sciences - PNAS (31-03-2009)“…A combination of spectroscopies and density functional theory calculations indicate that there are large temperature-dependent absorption spectral changes…”
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5
Pulse Dipolar ESR of Doubly Labeled Mini TAR DNA and Its Annealing to Mini TAR RNA
Published in Biophysical journal (17-02-2015)“…Pulse dipolar electron-spin resonance in the form of double electron electron resonance was applied to strategically placed, site-specifically attached pairs…”
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6
X- and W-Band EPR and Q-Band ENDOR Studies of the Flavin Radical in the Na+-Translocating NADH:Quinone Oxidoreductase from Vibrio cholerae
Published in Journal of the American Chemical Society (08-01-2003)“…Na(+)-NQR is the entry point for electrons into the respiratory chain of Vibrio cholerae. It oxidizes NADH, reduces ubiquinone, and uses the free energy of…”
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Spectroscopic Studies of the Met182Thr Mutant of Nitrite Reductase: Role of the Axial Ligand in the Geometric and Electronic Structure of Blue and Green Copper Sites
Published in Journal of the American Chemical Society (03-12-2003)“…A combination of spectroscopic methods and density functional calculations has been used to describe the electronic structure of the axial mutant (Met182Thr)…”
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8
Catalytic Function and Local Proton Structure at the Type 2 Copper of Nitrite Reductase: The Correlation of Enzymatic pH Dependence, Conserved Residues, and Proton Hyperfine Structure
Published in Biochemistry (Easton) (11-06-2002)“…Electron nuclear double resonance (ENDOR) of protons at Type 2 and Type 1 cupric active sites correlates with the enzymatic pH dependence, the mutation of…”
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9
Exchangeable proton ENDOR as a probe of the redox-active iron center in activated bleomycin and ferric bleomycin
Published in Dalton transactions : an international journal of inorganic chemistry (10-10-2017)“…Activated bleomycin (ABLM) is a drug-Fe(iii)-hydroperoxide complex kinetically competent in DNA attack (via H4' abstraction). This intermediate is relatively…”
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10
Regulation and Function of Cytochrome c′ in Rhodobacter sphaeroides 2.4.3
Published in Journal of Bacteriology (01-06-2005)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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11
Effect of freezing conditions on distances and their distributions derived from Double Electron Electron Resonance (DEER): A study of doubly-spin-labeled T4 lysozyme
Published in Journal of magnetic resonance (1997) (01-03-2012)“…[Display omitted] ► DEER with very rapid freezing yielded broader distributions than regular freezing. ► Neither method of freezing altered the distance…”
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12
Spectroscopic, Kinetic, and Electrochemical Characterization of Heterologously Expressed Wild-Type and Mutant Forms of Copper-Containing Nitrite Reductase from Rhodobacter sphaeroides 2.4.3
Published in Biochemistry (Easton) (28-04-1998)“…We report the development of a high-yield heterologous expression system for the copper-containing nitrite reductase from a denitrifying variant of Rhodobacter…”
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Anisotropic Fermi couplings due to large unquenched orbital angular momentum: Q-band (1)H, (14)N, and (11)B ENDOR of bis(trispyrazolylborate) cobalt(II)
Published in Journal of the American Chemical Society (05-08-2009)“…We report Q-band ENDOR of (1)H, (14)N, and (11)B at the g( parallel) extreme of the EPR spectrum of bis(trispyrazolylborate) cobalt(II) [Co(Tp)(2)] and two…”
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14
EPR−ENDOR of the Cu(I)NO Complex of Nitrite Reductase
Published in Journal of the American Chemical Society (11-10-2006)“…With limited reductant and nitrite under anaerobic conditions, copper-containing nitrite reductase (NiR) of Rhodobacter sphaeroides yielded endogenous NO and…”
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15
The Internal Dynamics of Mini c TAR DNA Probed by Electron Paramagnetic Resonance of Nitroxide Spin-Labels at the Lower Stem, the Loop, and the Bulge
Published in Biochemistry (Easton) (30-10-2012)“…Electron paramagnetic resonance (EPR) at 236.6 and 9.5 GHz probed the tumbling of nitroxide spin probes in the lower stem, in the upper loop, and near the…”
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16
Resolution of the Spectroscopy versus Crystallography Issue for NO Intermediates of Nitrite Reductase from Rhodobacter sphaeroides
Published in Journal of the American Chemical Society (29-08-2007)“…Copper nitrite reductase contains a T1 and T2 Cu center and catalyzes the one electron reduction of nitrite to NO. This study determines that reaction of the…”
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17
Rotational dynamics of HIV-1 nucleocapsid protein NCp7 as probed by a spin label attached by peptide synthesis
Published in Biopolymers (01-12-2008)“…2,2,6,6‐Tetramethylpiperidine‐1‐oxyl‐4‐amino‐4‐carboxylic acid (TOAC) spin label was attached at the N‐terminal position to interrogate the dynamics of the…”
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HIV-1 Nucleocapsid Protein NCp7 and Its RNA Stem Loop 3 Partner: Rotational Dynamics of Spin-Labeled RNA Stem Loop 3
Published in Biochemistry (Easton) (23-09-2008)“…The tumbling dynamics of a 20-mer HIV-1 RNA stem loop 3 spin-labeled at the 5′ position were probed in the nanosecond time range. This RNA interacted with the…”
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The Role of Arginine-127 at the Proximal NO-Binding Site in Determining the Electronic Structure and Function of 5-Coordinate NO-Heme in Cytochrome c′ of Rhodobacter sphaeroides
Published in Biochemistry (Easton) (29-09-2009)“…Cytochrome c′ is a heme protein from a denitrifying variant of Rhodobacter sphaeroides which may serve to store and transport metabolic NO while protecting…”
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20
Subsecond time-resolved spin trapping followed by stopped-flow EPR of Fenton reaction products
Published in Journal of the American Chemical Society (01-06-1993)Get full text
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