Mortality and Gram-negative rod bacteraemia in the intensive care unit

This study identified 37 intensive care unit (ICU) patients with Gram-negative rod (GNR) bacteraemia. The sources, causative organisms and mortality of Gram-negative bacteraemia were consistent with historical series. Antibiotic resistance among well-described species with a propensity for antimicro...

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Bibliographic Details
Published in:	The Journal of hospital infection Vol. 62; no. 4; pp. 453 - 457
Main Authors:	Gardiner, D.F., Scholand, S.J., Babinchak, T.
Format:	Journal Article
Language:	English
Published:	Kent Elsevier Ltd 01-04-2006 Elsevier
Subjects:	Anti-Bacterial Agents - therapeutic use APACHE Bactaeremia Bacterial diseases Bacterial sepsis Biological and medical sciences Drug Resistance, Bacterial Female Gram-Negative Bacteria - classification Gram-Negative Bacteria - isolation & purification Gram-Negative Bacteria - pathogenicity Gram-Negative Bacterial Infections - classification Gram-Negative Bacterial Infections - microbiology Gram-Negative Bacterial Infections - mortality Human bacterial diseases Humans Infectious diseases Intensive care unit Intensive Care Units Male Medical sciences Middle Aged Mortality Mortality Intensive care unit Bactaeremia Infection Prognosis Bacteriosis Bacteremia Gram negative bacteria
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Summary:	This study identified 37 intensive care unit (ICU) patients with Gram-negative rod (GNR) bacteraemia. The sources, causative organisms and mortality of Gram-negative bacteraemia were consistent with historical series. Antibiotic resistance among well-described species with a propensity for antimicrobial resistance was the most common reason for ineffective antibiotic administration. This study emphasizes the importance of antibiotic resistance in antimicrobial selection and the power of Acute Physiology and Chronic Health Evaluation criteria for predicting patient mortality.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0195-6701 1532-2939
DOI:	10.1016/j.jhin.2005.10.004