Search Results - "Schofield, P J"

Transdermal buprenorphine plus oral paracetamol vs an oral codeine-paracetamol combination for osteoarthritis of hip and/or knee: a randomised trial by Conaghan, P.G, O’Brien, C.M, Wilson, M, Schofield, J.P

“…Summary Objective Low-dose transdermal opioids offer a new therapeutic option for osteoarthritis (OA). This study compared symptom relief obtained with…”
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Identification and localization of alternately spliced mRNAs for vascular endothelial growth factor in human uterus and estrogen regulation in endometrial carcinoma cell lines by Charnock-Jones, D S, Sharkey, A M, Rajput-Williams, J, Burch, D, Schofield, J P, Fountain, S A, Boocock, C A, Smith, S K

“…Repair of human endometrium after menstruation and preparation of the endometrium for implantation involves profound angiogenic changes. Vascular endothelial…”
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Sputum proteomic signature of gastro-oesophageal reflux in patients with severe asthma by Tariq, K., Schofield, J.P.R., Nicholas, B.L., Burg, D., Brandsma, J., Bansal, A.T., Wilson, S.J., Lutter, R., Fowler, S.J., Bakke, Caruso, M., Dahlen, B., Horváth, I., Krug, N., Montuschi, P., Sanak, M., Sandström, T., Geiser, T., Pandis, I., Sousa, A.R., Adcock, I.M., Shaw, D.E., Auffray, C., Howarth, P.H., Sterk, P.J., Chung, K.F., Skipp, P.J., Dimitrov, B., Djukanović, R.

“…Gastro-oesophageal reflux disease (GORD) has long been associated with poor asthma control without an established cause-effect relationship. 610 asthmatics…”
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Characterization of genomic structure and polymorphisms in the human carbamyl phosphate synthetase I gene by Summar, M.L., Hall, L.D., Eeds, A.M., Hutcheson, H.B., Kuo, A.N., Willis, A.S., Rubio, V., Arvin, M.K., Schofield, J.P., Dawson, E.P.

“…Human carbamyl phosphate synthetase I (CPSI) is an essential hepatic enzyme that initiates the urea cycle. Deficiency of this enzyme usually results in lethal…”
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Non-viral approaches to gene therapy by Schofield, J P, Caskey, C T

“…There have been rapid advances in the development of non-viral techniques for gene transfer. Although viruses are highly evolved to infect mammalian cells,…”
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Salinity effects on behavioural response to hypoxia in the non-native Mayan cichlid Cichlasoma urophthalmus from Florida Everglades wetlands by Schofield, P. J., Loftus, W. F., Fontaine, J. A.

“…This study quantified the hypoxia tolerance of the Mayan cichlid Cichlasoma urophthalmus over a range of salinities. The species was very tolerant of hypoxia,…”
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Identification of C-type natriuretic peptide in heart of spiny dogfish shark (Squalus acanthias) by Schofield, J P, Jones, D S, Forrest, Jr, J N

“…An unidentified atrial natriuretic peptide (ANP)-like substance is the principal hormone regulating NaCl secretion in the shark rectal gland, an epithelial…”
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Endothelin-1 mRNA is widely expressed in porcine and human tissues by NUMEZ, D. J. R, BROWN, M. J, DAVENPORT, A. P, NEYLON, C. B, SCHOFIELD, J. P, WYSE, R. K

“…Endothelin-1 (ET-1) is a potent vasoconstrictor peptide isolated from porcine endothelial cells. We have previously demonstrated widespread binding sites for…”
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Interactions between Nile perch, Lates niloticus, and other fishes in Lake Nabugabo, Uganda by SCHOFIELD, P. J, CHAPMAN, L. J

“…The introduction of the predatory Nile perch, Lates niloticus, into the Lake Victoria basin coincided with a dramatic decline in fish species richness and…”
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Molecular studies on an ancient gene encoding for carbamoyl-phosphate synthetase by Schofield, J P

“…1. Carbamoyl-phosphate synthetase (EC 6.3.5.5.) catalyses the synthesis of carbamoyl phosphate, the immediate precursor of arginine and pyrimidine…”
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L-Arginine transport and metabolism in Giardia intestinalis support its position as a transition between the prokaryotic and eukaryotic kingdoms by Knodler, Leigh A, Schofield, Philip J, Edwards, Michael R

“…School of Biochemistry and Molecular Genetics, University of New South Wales, Sydney, NSW 2052, Australia ABSTRACT Arginine is metabolized by the arginine…”
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Mice deficient in the urea‐cycle enzyme, carbamoyl phosphate synthetase i, die during the early neonatal period from hyperammonemia by Schofield, J. Paul, Schofield, J. Paul, Cox, Timothy M., Caskey, C. Thomas, Wakamiya, Maki

“…Ammonia liberated during amino acid catabolism in mammals is highly neurotoxic and is detoxified by the five enzymes of the urea cycle that are expressed…”
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A novel and simple colorimetric method for screening Giardia intestinalis and anti-giardial activity in vitro by Kang, E W, Clinch, K, Furneaux, R H, Harvey, J E, Schofield, P J, Gero, A M

“…A new and simple colorimetric method has been developed for determining activity in vitro against Giardia intestinalis. The microtitre plate assay is based…”
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rapid method for isolating high quality plasmid DNA suitable for DNA sequencing by Stephen, D, Jones, C, Schofield, J.P

“…Images…”
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The role of alanine in the acute response of Giardia intestinalis to hypo-osmotic shock by Park, Jeong H, Schofield, Philip J, Edwards, Michael R

“…School of Biochemistry and Molecular Genetics, University of New South Wales, Sydney, NSW 2052, Australia ABSTRACT Summary: The effect of medium…”
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Habitat selection of two gobies ( Microgobius gulosus, Gobiosoma robustum): influence of structural complexity, competitive interactions, and presence of a predator by Schofield, Pamela J

“…Herein I compare the relative importance of preference for structurally complex habitat against avoidance of competitors and predators in two benthic fishes…”
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Role of K+ and amino acids in osmoregulation by the free-living microaerophilic protozoon Hexamita inflata by Biagini, Giancarlo A, Kirk, Kiaran, Schofield, Phillip J, Edwards, Michael R

“…School of Biochemistry and Molecular Biology, University of New South Wales, Sydney, NSW 2052, Australia 1 Division of Biochemistry and Molecular Biology,…”
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Regions of Human Chromosome 2 (2q32–q35) and Mouse Chromosome 1 Show Synteny with the Pufferfish Genome (Fugu rubripes) by Schofield, J.Paul, Elgar, Greg, Greystrong, John, Lye, Georgina, Deadman, Rebecca, Micklem, Gos, King, Andrew, Brenner, Sydney, Vaudin, Mark

“…We have isolated and sequenced a cosmid clone from the compact genome of the Japanese pufferfish (Fugu rubripes) containing portions of three genes that have…”
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The arginine dihydrolase pathway is present in Giardia intestinalis by Schofield, P J, Costello, M, Edwards, M R, O'Sullivan, W J

“…Growth of Giardia intestinalis in Diamond's TYI-S-33 medium is characterized by a rapid depletion of the arginine in the medium, and concurrent production of…”
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Pathologic gene expression in Gaucher disease: up-regulation of cysteine proteinases including osteoclastic cathepsin K by Moran, Mary Teresa, Schofield, J. Paul, Hayman, Alison R., Shi, Guo-Ping, Young, Elisabeth, Cox, Timothy M.

“…Deficiency of lysosomal acid β-glucosidase induces glycolipid storage in the macrophages of Gaucher disease but the pathways of multisystem tissue injury and…”
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