Search Results - "Schofield, Mandy"
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Targeting F-actin stress fibers to suppress the dedifferentiated phenotype in chondrocytes
Published in European journal of cell biology (01-06-2024)“…Actin is a central mediator of the chondrocyte phenotype. Monolayer expansion of articular chondrocytes on tissue culture polystyrene, for cell-based repair…”
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Journal Article -
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Stress deprivation of tendon explants or Tpm3.1 inhibition in tendon cells reduces F-actin to promote a tendinosis-like phenotype
Published in Molecular biology of the cell (01-12-2022)“…Actin is a central mediator between mechanical force and cellular phenotype. In tendons, it is speculated that mechanical stress deprivation regulates gene…”
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Journal Article -
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Mitochondrial genome of an Allegheny Woodrat (Neotoma magister)
Published in Mitochondrial DNA. Part B. Resources (22-02-2018)“…The Allegheny woodrat (Neotoma magister) is endemic to the eastern United States. Population numbers have decreased rapidly over the last four decades due to…”
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Journal Article -
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Targeting F-Actin to Promote the Redifferentiation of Chondrocytes
Published 01-01-2023“…Articular cartilage is incapable of self- repair and any damage to the tissue results in degradation leading to Osteoarthritis. To prevent Osteoarthritis…”
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Dissertation