Search Results - "Schoepflin, Anja"
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pH-Sensing G Protein-Coupled Receptor OGR1 (GPR68) Expression and Activation Increases in Intestinal Inflammation and Fibrosis
Published in International journal of molecular sciences (26-01-2022)“…Local extracellular acidification occurs at sites of inflammation. Proton-sensing ovarian cancer G-protein-coupled receptor 1 (OGR1, also known as GPR68)…”
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A novel approach for reliable microarray analysis of microdissected tumor cells from formalin-fixed and paraffin-embedded colorectal cancer resection specimens
Published in Journal of molecular medicine (Berlin, Germany) (01-02-2009)“…We present a novel approach for microarray analysis of RNA derived from microdissected cells of routinely formalin-fixed and paraffin-embedded (FFPE) cancer…”
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Frequent Detection of Merkel Cell Polyomavirus in Human Merkel Cell Carcinomas and Identification of a Unique Deletion in the VP1 Gene
Published in Cancer research (Chicago, Ill.) (01-07-2008)“…Merkel cell carcinoma (MCC) is a rare but very aggressive human malignancy of the elderly or immunosuppressed patients. Recently, the clonal integration of a…”
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EGFR, HER2 and HER3 dimerization patterns guide targeted inhibition in two histotypes of esophageal cancer
Published in International journal of cancer (01-10-2014)“…Receptor tyrosine kinases (RTKs) are in the focus of targeted therapy for epithelial tumors. Our study addressed the role of EGFR, HER2 and HER3 expression and…”
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Class I and III HDACs and loss of active chromatin features contribute to epigenetic silencing of CDX1 and EPHB tumor suppressor genes in colorectal cancer
Published in Epigenetics (01-05-2011)“…Aberrant Wnt/β-catenin signaling is a driving force during initiation and progression of colorectal cancer. Yet, the Wnt/β-catenin targets CDX1, EPHB2, EPHB3…”
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The immunohistochemical staining pattern of Gab2 correlates with distinct stages of chronic myeloid leukemia
Published in Human pathology (01-05-2011)“…Summary Grb2-associated binder 2 protein (Gab2) is a member of scaffold proteins, playing crucial roles in (receptor-) tyrosine kinase and cytokine signaling…”
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Predictive Molecular Markers for Colorectal Cancer Patients With Resected Liver Metastasis and Adjuvant Chemotherapy
Published in Gastroenterology (New York, N.Y. 1943) (01-12-2007)“…Background & Aims: The aims of the study were to evaluate the predictive value of 8 candidate molecular markers for colorectal cancer (CRC) patients receiving…”
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Occurrence of Aurora A positive multipolar mitoses in distinct molecular classes of colorectal carcinomas and effect of Aurora A inhibition
Published in Molecular carcinogenesis (01-09-2012)“…Aurora A “over‐”expression may induce supernumerary centrosomes, respective multipolar mitoses, and aneuploidy. Here, we examined Aurora A positive multipolar…”
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Cyclin D1 expression is induced by viral BARF1 and is overexpressed in EBV-associated gastric cancer
Published in Virchows Archiv : an international journal of pathology (01-06-2008)“…Approximately 10% of gastric carcinomas (GC) worldwide are associated with Epstein–Barr virus (EBV). GC is one of the most frequent human malignancies…”
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