Search Results - "Schoenfeld, Robert A."
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Frataxin deficiency leads to defects in expression of antioxidants and Nrf2 expression in dorsal root ganglia of the Friedreich's ataxia YG8R mouse model
Published in Antioxidants & redox signaling (01-11-2013)“…Oxidative stress is thought to be involved in Friedreich's ataxia (FRDA), yet it has not been demonstrated in the target neurons that are first to degenerate…”
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Journal Article -
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Decreased Superoxide Production in Macrophages of Long-lived p66Shc Knock-out Mice
Published in The Journal of biological chemistry (08-01-2010)“…A decrease in reactive oxygen species (ROS) production has been associated with extended life span in animal models of longevity. Mice deficient in the p66Shc…”
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Journal Article -
3
Frataxin deficiency alters heme pathway transcripts and decreases mitochondrial heme metabolites in mammalian cells
Published in Human molecular genetics (15-12-2005)“…Deficiency of the frataxin mRNA alters the transcriptome, triggering neuro- and cardiodegeneration in Friedreich's ataxia. We microarrayed murine…”
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Journal Article -
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Synthesis and characterization of mitoQ and idebenone analogues as mediators of oxygen consumption in mitochondria
Published in Bioorganic & medicinal chemistry (01-09-2010)“…Analogues of mitoQ and idebenone were synthesized to define the structural elements that support oxygen consumption in the mitochondrial respiratory chain…”
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Journal Article -
5
The genomic structure of delta conotoxins and other O-superfamily conotoxins
Published 01-01-1999“…Conotoxins are short, cysteine-rich peptide toxins produced by marine gastropods of the genus Conus. The venom of each species is estimated to contain 40–200…”
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Dissertation