Search Results - "Schober, Michelle"

Neurologic Manifestations of COVID-19 in Children: Emerging Pathophysiologic Insights by Schober, Michelle E., Pavia, Andrew T., Bohnsack, John F.

“…The COVID-19 pandemic has affected mortality and morbidity across all ages, including children. Neurologic manifestations of coronavirus disease 2019, ranging…”
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Acute central and peripheral nervous system injury associated with coronavirus disease 2019: recognition and treatment strategies by Simon, Dennis W., Schober, Michelle E.

“…Purpose of review Acute central and peripheral nervous system injury may occur in association with coronavirus disease 2019 (COVID-19) caused by infection with…”
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Prevalence and Risk Factors of Neurologic Manifestations in Hospitalized Children Diagnosed with Acute SARS-CoV-2 or MIS-C by Fink, Ericka L., Robertson, Courtney L., Wainwright, Mark S., Roa, Juan D., Lovett, Marlina E., Stulce, Casey, Yacoub, Mais, Potera, Renee M., Zivick, Elizabeth, Holloway, Adrian, Nagpal, Ashish, Wellnitz, Kari, Czech, Theresa, Even, Katelyn M., Brunow de Carvalho, Werther, Rodriguez, Isadora Souza, Schwartz, Stephanie P., Walker, Tracie C., Campos-Miño, Santiago, Dervan, Leslie A., Geneslaw, Andrew S., Sewell, Taylor B., Pryce, Patrice, Silver, Wendy G., Lin, Jieru Egeria, Vargas, Wendy S., Topjian, Alexis, Alcamo, Alicia M., McGuire, Jennifer L., Domínguez Rojas, Jesus Angel, Muñoz, Jaime Tasayco, Hong, Sue J., Muller, William J., Doerfler, Matthew, Williams, Cydni N., Drury, Kurt, Bhagat, Dhristie, Nelson, Aaron, Price, Dana, Dapul, Heda, Santos, Laura, Kahoud, Robert, Francoeur, Conall, Appavu, Brian, Guilliams, Kristin P., Agner, Shannon C., Walson, Karen H., Rasmussen, Lindsey, Janas, Anna, Ferrazzano, Peter, Farias-Moeller, Raquel, Snooks, Kellie C., Chang, Chung-Chou H., Yun, James, Schober, Michelle E.

“…Our objective was to characterize the frequency, early impact, and risk factors for neurological manifestations in hospitalized children with acute severe…”
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EPO improved neurologic outcome in rat pups late after traumatic brain injury by Schober, Michelle E., Requena, Daniela F., Rodesch, Christopher K.

“…In adult rats, erythropoietin improved outcomes early and late after traumatic brain injury, associated with increased levels of Brain Derived Neurotrophic…”
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Docosahexaenoic acid decreased neuroinflammation in rat pups after controlled cortical impact by Schober, Michelle E., Requena, Daniela F., Casper, T. Charles, Velhorst, Amy K., Lolofie, Alyssa, McFarlane, Katelyn E., Otto, Taylor E., Terry, Cynthia, Gensel, John C.

“…Traumatic brain injury (TBI) is the leading cause of acquired neurologic disability in children, yet specific therapies to treat TBI are lacking. Therapies…”
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Effects of controlled cortical impact and docosahexaenoic acid on rat pup fatty acid profiles by Schober, Michelle E., Requena, Daniela F., Maschek, J. Alan, Cox, James, Parra, Leonardo, Lolofie, Alyssa

“…•DHA decreased injury, oxidative stress and inflammation in rat pup brain after CCI.•In rat pups, CCI and craniotomy each induce a mild brain DHA…”
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Enhancing Understanding and Overcoming Barriers in Brain Death Determination Using Standardized Education: A Call to Action by Jaffa, Matthew N., Kirschen, Matthew P., Tuppeny, Misti, Reynolds, Alexandra S., Lim-Hing, Krista, Hargis, Mitch, Choi, Richard K., Schober, Michelle E., LaBuzetta, Jamie Nicole

“…Introduction The integrity of the Brain Death or Death by Neurologic Criteria (BD/DNC) evaluation is crucial, as the presence of a single reflex or breath is…”
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Global Consortium Study of Neurological Dysfunction in COVID-19 (GCS-NeuroCOVID): Study Design and Rationale by Frontera, Jennifer, Mainali, Shraddha, Fink, Ericka L., Robertson, Courtney L., Schober, Michelle, Ziai, Wendy, Menon, David, Kochanek, Patrick M., Suarez, Jose I., Helbok, Raimund, McNett, Molly, Chou, Sherry H.-Y.

“…Background As the COVID-19 pandemic developed, reports of neurological dysfunctions spanning the central and peripheral nervous systems have emerged. The…”
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Response to “Some Contributions on Standardized Education for Brain Death Determination” by Jaffa, Matthew N., Kirschen, Matthew P., Tuppeny, Misti, Reynolds, Alexandra S., Lim-Hing, Krista, Hargis, Mitch, Choi, Richard K., Schober, Michelle E., LaBuzetta, Jamie Nicole

“…[...]we also recognize the valid perspective that using organ procurement organization funding to drive clinical training to diagnose BD/DNC represents a…”
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Dietary Docosahexaenoic Acid Improves Cognitive Function, Tissue Sparing, and Magnetic Resonance Imaging Indices of Edema and White Matter Injury in the Immature Rat after Traumatic Brain Injury by Schober, Michelle E, Requena, Daniela F, Abdullah, Osama M, Casper, T Charles, Beachy, Joanna, Malleske, Daniel, Pauly, James R

“…Traumatic brain injury (TBI) is the leading cause of acquired neurologic disability in children. Specific therapies to treat acute TBI are lacking. Cognitive…”
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Temporal response profiles of serum ubiquitin C-terminal hydrolase-L1 and the 145-kDa alpha II-spectrin breakdown product after severe traumatic brain injury in children by Metzger, Ryan R, Sheng, Xiaoming, Niedzwecki, Christian M, Bennett, Kimberly S, Morita, Denise C, Zielinski, Brandon, Schober, Michelle E

“…Traumatic brain injury (TBI) is the leading cause of acquired disability among children. Brain injury biomarkers may serve as useful diagnostic and prognostic…”
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Corrigendum: Post-discharge outcomes of hospitalized children diagnosed with acute SARS-CoV-2 or MIS-C by Fink, Ericka L, Alcamo, Alicia M, Lovett, Marlina, Hartman, Mary, Williams, Cydni, Garcia, Angela, Rasmussen, Lindsey, Pal, Ria, Drury, Kurt, MackDiaz, Elizabeth, Ferrazzano, Peter A, Dervan, Leslie, Appavu, Brian, Snooks, Kellie, Stulce, Casey, Rubin, Pamela, Pate, Bianca, Toney, Nicole, Robertson, Courtney L, Wainwright, Mark S, Roa, Juan D, Schober, Michelle E, Slomine, Beth S

“…[This corrects the article DOI: 10.3389/fped.2024.1340385.]…”
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Post-discharge outcomes of hospitalized children diagnosed with acute SARS-CoV-2 or MIS-C by Fink, Ericka L, Alcamo, Alicia M, Lovett, Marlina, Hartman, Mary, Williams, Cydni, Garcia, Angela, Rasmussen, Lindsey, Pal, Ria, Drury, Kurt, MackDiaz, Elizabeth, Ferrazzano, Peter A, Dervan, Leslie, Appavu, Brain, Snooks, Kellie, Stulce, Casey, Rubin, Pamela, Pate, Bianca, Toney, Nicole, Robertson, Courtney L, Wainwright, Mark S, Roa, Juan D, Schober, Michelle E, Slomine, Beth S

“…Hospitalized children diagnosed with SARS-CoV-2-related conditions are at risk for new or persistent symptoms and functional impairments. Our objective was to…”
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Alpha II Spectrin breakdown products in immature Sprague Dawley rat hippocampus and cortex after traumatic brain injury by Schober, Michelle E, Requena, Daniela F, Davis, Lizeth J, Metzger, Ryan R, Bennett, Kimberly S, Morita, Denise, Niedzwecki, Christian, Yang, Zhihui, Wang, Kevin K.W

“…Abstract After traumatic brain injury (TBI), proteolysis of Alpha II Spectrin by Calpain 1 produces 145 Spectrin breakdown products (SBDPs) while proteolysis…”
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Erythropoietin improved cognitive function and decreased hippocampal caspase activity in rat pups after traumatic brain injury by Schober, Michelle E, Requena, Daniela F, Block, Benjamin, Davis, Lizeth J, Rodesch, Christopher, Casper, T Charles, Juul, Sandra E, Kesner, Raymond P, Lane, Robert H

“…Traumatic brain injury (TBI) is a leading cause of acquired neurologic disability in children. Erythropoietin (EPO), an anti-apoptotic cytokine, improved…”
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A Virtual Community of Practice: An International Educational Series in Pediatric Neurocritical Care by Erklauer, Jennifer C, Thomas, Ajay X, Hong, Sue J, Appavu, Brian L, Carpenter, Jessica L, Chiriboga-Salazar, Nicolas R, Ferrazzano, Peter A, Goldstein, Zachary, Griffith, Jennifer L, Guilliams, Kristin P, Kirschen, Matthew P, Lidsky, Karen, Lovett, Marlina E, McLaughlin, Brandon, Munoz Pareja, Jennifer C, Murphy, Sarah, O?Donnell, Wendy, Riviello, James J, Schober, Michelle E, Topjian, Alexis A, Wainwright, Mark S, Simon, Dennis W

“…Pediatric neurocritical care (PNCC) is a rapidly growing field. Challenges posed by the COVID-19 pandemic on trainee exposure to educational opportunities…”
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Traumatic brain injury increased IGF-1B mRNA and altered IGF-1 exon 5 and promoter region epigenetic characteristics in the rat pup hippocampus by Schober, Michelle E, Ke, Xingrao, Xing, Bohan, Block, Benjamin P, Requena, Daniela F, McKnight, Robert, Lane, Robert H

“…Traumatic brain injury (TBI) is a major cause of acquired cognitive disability in childhood. Such disability may be blunted by enhancing the brain's endogenous…”
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Intrauterine growth retardation affects expression and epigenetic characteristics of the rat hippocampal glucocorticoid receptor gene by Ke, Xingrao, Schober, Michelle E, McKnight, Robert A, O'Grady, Shannon, Caprau, Diana, Yu, Xing, Callaway, Christopher W, Lane, Robert H

“…Studies in humans and rats suggest that intrauterine growth retardation (IUGR) permanently resets the hypothalamic-pituitary-adrenal (HPA) axis. HPA axis…”
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Severe Pediatric Neurological Manifestations With SARS-CoV-2 or MIS-C Hospitalization and New Morbidity by Francoeur, Conall, Alcamo, Alicia M, Robertson, Courtney L, Wainwright, Mark S, Roa, Juan D, Lovett, Marlina E, Stulce, Casey, Yacoub, Mais, Potera, Renee M, Zivick, Elizabeth, Holloway, Adrian, Nagpal, Ashish, Wellnitz, Kari, Even, Katelyn M, Brunow de Carvalho, Werther, Rodriguez, Isadora S, Schwartz, Stephanie P, Walker, Tracie C, Campos-Miño, Santiago, Dervan, Leslie A, Geneslaw, Andrew S, Sewell, Taylor B, Pryce, Patrice, Silver, Wendy G, Lin, Jieru E, Vargas, Wendy S, Topjian, Alexis, McGuire, Jennifer L, Domínguez Rojas, Jesus Angel, Tasayco-Muñoz, Jaime, Hong, Sue J, Muller, William J, Doerfler, Matthew, Williams, Cydni N, Drury, Kurt, Bhagat, Dhristie, Nelson, Aaron, Price, Dana, Dapul, Heda, Santos, Laura, Kahoud, Robert, Appavu, Brian, Guilliams, Kristin P, Agner, Shannon C, Walson, Karen H, Rasmussen, Lindsey, Pal, Ria, Janas, Anna, Ferrazzano, Peter, Farias-Moeller, Raquel, Snooks, Kellie C, Chang, Chung-Chou H, Iolster, Tomás, Erklauer, Jennifer C, Jorro Baron, Facundo, Wassmer, Evangeline, Yoong, Michael, Jardine, Michelle, Mohammad, Zoha, Deep, Akash, Kendirli, Tanil, Lidsky, Karen, Dallefeld, Samantha, Flockton, Helen, Agrawal, Shruti, Siruguppa, Krishna Sumanth, Waak, Michaela, Gutiérrez-Mata, Alfonso, Butt, Warwick, Bogantes-Ledezma, Sixto, Sevilla-Acosta, Fabricio, Umaña-Calderón, Andres, Ulate-Campos, Adriana, Yock-Corrales, Adriana, Talisa, Victor Brodzik, Kanthimathinathan, Hari Krishnan, Schober, Michelle E, Fink, Ericka L

“…Neurological manifestations during acute SARS-CoV-2-related multisystem inflammatory syndrome in children (MIS-C) are common in hospitalized patients younger…”
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Early and sustained increase in the expression of hippocampal IGF-1, but not EPO, in a developmental rodent model of traumatic brain injury by Schober, Michelle E, Block, Benjamin, Beachy, Joanna C, Statler, Kimberly D, Giza, Christopher C, Lane, Robert H

“…Pediatric traumatic brain injury (pTBI) is the leading cause of traumatic death and disability in children in the United States. Impaired learning and memory…”
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