Search Results - "Schober, Andreas"

Chemokines in Vascular Dysfunction and Remodeling by Schober, Andreas

“…Vascular remodeling stands for structural changes of the vessel wall in response to various noxious stimuli, which results in reorganization of the vessel wall…”
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MicroRNA regulation of macrophages in human pathologies by Wei, Yuanyuan, Schober, Andreas

“…Macrophages play a crucial role in the innate immune system and contribute to a broad spectrum of pathologies, like in the defence against infectious agents,…”
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Mechanisms of MicroRNAs in Atherosclerosis by Schober, Andreas, Weber, Christian

“…The maladaptation of endothelial cells to disturbed flow at arterial bifurcations increases permeability for lipoproteins. Additional injury by chemically…”
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Lysophosphatidic acid in atherosclerotic diseases by Schober, Andreas, Siess, Wolfgang

“…Lysophosphatidic acid (LPA) is a potent bioactive phospholipid. As many other biological active lipids, LPA is an autacoid: it is formed locally on demand, and…”
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Chemokines and microRNAs in atherosclerosis by Hartmann, Petra, Schober, Andreas, Weber, Christian

“…The crucial role of chemokines in the initiation and progression of atherosclerosis has been widely recognized. Through essential functions in leukocyte…”
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MicroRNA-mediated mechanisms of the cellular stress response in atherosclerosis by Schober, Andreas, Nazari-Jahantigh, Maliheh, Weber, Christian

“…Key Points Atherosclerosis develops mainly at branching points of large-sized and medium-sized arteries, where flow turbulence triggers chronic endothelial…”
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Pathogenic arterial remodeling: the good and bad of microRNAs by Wei, Yuanyuan, Schober, Andreas, Weber, Christian

“…A number of cardiovascular diseases, such as restenosis, aneurysm, and atherosclerosis, lead to vascular remodeling associated with complex adaptive reactions…”
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MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1 by Schober, Andreas, Nazari-Jahantigh, Maliheh, Wei, Yuanyuan, Bidzhekov, Kiril, Gremse, Felix, Grommes, Jochen, Megens, Remco T A, Heyll, Kathrin, Noels, Heidi, Hristov, Michael, Wang, Shusheng, Kiessling, Fabian, Olson, Eric N, Weber, Christian

“…Atherosclerotic lesions develop preferentially at sites of disturbed blood flow. As shown by Christian Weber and his coworkers, this predilection stems from…”
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MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages by Nazari-Jahantigh, Maliheh, Wei, Yuanyuan, Noels, Heidi, Akhtar, Shamima, Zhou, Zhe, Koenen, Rory R, Heyll, Kathrin, Gremse, Felix, Kiessling, Fabian, Grommes, Jochen, Weber, Christian, Schober, Andreas

“…Macrophages in atherosclerotic plaques drive inflammatory responses, degrade lipoproteins, and phagocytose dead cells. MicroRNAs (miRs) control the…”
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Dicer in Macrophages Prevents Atherosclerosis by Promoting Mitochondrial Oxidative Metabolism by Wei, Yuanyuan, Corbalán-Campos, Judit, Gurung, Rashmi, Natarelli, Lucia, Zhu, Mengyu, Exner, Nicole, Erhard, Florian, Greulich, Franziska, Geißler, Claudia, Uhlenhaut, N Henriette, Zimmer, Ralf, Schober, Andreas

“…BACKGROUND:Alternative macrophage activation, which relies on mitochondrial oxidative metabolism, plays a central role in the resolution of inflammation and…”
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Macrophage MicroRNAs as Therapeutic Targets for Atherosclerosis, Metabolic Syndrome, and Cancer by Wei, Yuanyuan, Zhu, Mengyu, Schober, Andreas

“…Macrophages play a crucial role in the innate immune system and contribute to a broad spectrum of pathologies in chronic inflammatory diseases. MicroRNAs…”
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A Selectively Permeable Membrane for Enhancing Cyclability of Organic Sodium-Ion Batteries by Wang, Chengliang, Jiang, Cheng, Xu, Yang, Liang, Liying, Zhou, Min, Jiang, Jianjun, Singh, Sukhdeep, Zhao, Huaping, Schober, Andreas, Lei, Yong

“…A novel strategy to enhance the cyclability of organic sodium‐ion batteries is developed by applying a selectively permeable membrane to allow the passage of…”
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miR-103 promotes endothelial maladaptation by targeting lncWDR59 by Natarelli, Lucia, Geißler, Claudia, Csaba, Gergely, Wei, Yuanyuan, Zhu, Mengyu, di Francesco, Andrea, Hartmann, Petra, Zimmer, Ralf, Schober, Andreas

“…Blood flow at arterial bifurcations and curvatures is naturally disturbed. Endothelial cells (ECs) fail to adapt to disturbed flow, which transcriptionally…”
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Chemokines in vascular remodeling by Schober, Andreas, Zernecke, Alma

“…The arterial vessel wall response to a variety of injuries consists in structural changes, which can result in luminal narrowing and aggravation of the…”
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Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection by Zernecke, Alma, Bidzhekov, Kiril, Noels, Heidi, Shagdarsuren, Erdenechimeg, Gan, Lin, Denecke, Bernd, Hristov, Mihail, Köppel, Thomas, Jahantigh, Maliheh Nazari, Lutgens, Esther, Wang, Shusheng, Olson, Eric N, Schober, Andreas, Weber, Christian

“…Apoptosis is a pivotal process in embryogenesis and postnatal cell homeostasis and involves the shedding of membranous microvesicles termed apoptotic bodies…”
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Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4 by Hartmann, Petra, Zhou, Zhe, Natarelli, Lucia, Wei, Yuanyuan, Nazari-Jahantigh, Maliheh, Zhu, Mengyu, Grommes, Jochen, Steffens, Sabine, Weber, Christian, Schober, Andreas

“…MicroRNAs regulate the maladaptation of endothelial cells (ECs) to naturally occurring disturbed blood flow at arterial bifurcations resulting in arterial…”
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Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium by Gomez, Ingrid, Ward, Ben, Souilhol, Celine, Recarti, Chiara, Ariaans, Mark, Johnston, Jessica, Burnett, Amanda, Mahmoud, Marwa, Luong, Le Anh, West, Laura, Long, Merete, Parry, Sion, Woods, Rachel, Hulston, Carl, Benedikter, Birke, Niespolo, Chiara, Bazaz, Rohit, Francis, Sheila, Kiss-Toth, Endre, van Zandvoort, Marc, Schober, Andreas, Hellewell, Paul, Evans, Paul C., Ridger, Victoria

“…Neutrophils are implicated in the pathogenesis of atherosclerosis but are seldom detected in atherosclerotic plaques. We investigated whether…”
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Causes of in-hospital cardiac arrest and influence on outcome by Wallmuller, Christian, Meron, Giora, Kurkciyan, Istepan, Schober, Andreas, Stratil, Peter, Sterz, Fritz

“…Abstract Aim of the study To evaluate the relationship between cause and outcome of in-hospital cardiac arrest. Methods Retrospective analysis of resuscitation…”
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MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment by Bernhagen, Jürgen, Weber, Christian, Krohn, Regina, Lue, Hongqi, Gregory, Julia L, Zernecke, Alma, Koenen, Rory R, Dewor, Manfred, Georgiev, Ivan, Schober, Andreas, Leng, Lin, Kooistra, Teake, Fingerle-Rowson, Günter, Ghezzi, Pietro, Kleemann, Robert, McColl, Shaun R, Bucala, Richard, Hickey, Michael J

“…The cytokine macrophage migration inhibitory factor (MIF) plays a critical role in inflammatory diseases and atherogenesis. We identify the chemokine receptors…”
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Endothelial ENPP2 (Ectonucleotide Pyrophosphatase/Phosphodiesterase 2) Increases Atherosclerosis in Female and Male Mice by Karshovska, Ela, Mohibullah, Rokia, Zhu (朱梦瑜), Mengyu, Zahedi, Farima, Thomas, Dominique, Magkrioti, Christiana, Geissler, Claudia, Megens, Remco T.A., Bianchini, Mariaelvy, Nazari-Jahantigh, Maliheh, Ferreirós, Nerea, Aidinis, Vassilis, Schober, Andreas

“…Background: Maladapted endothelial cells (ECs) secrete ENPP2 (ectonucleotide pyrophosphatase/phosphodiesterase 2; autotaxin)—a lysophospholipase D that…”
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