Search Results - "Schnyder, Bruno"

IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice by Gasse, Pamela, Mary, Caroline, Guenon, Isabelle, Noulin, Nicolas, Charron, Sabine, Schnyder-Candrian, Silvia, Schnyder, Bruno, Akira, Shizuo, Quesniaux, Valérie F J, Lagente, Vincent, Ryffel, Bernhard, Couillin, Isabelle

“…The molecular mechanisms of acute lung injury resulting in inflammation and fibrosis are not well established. Here we investigate the roles of the IL-1…”
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Interleukin-17 is a negative regulator of established allergic asthma by Schnyder-Candrian, Silvia, Togbe, Dieudonnée, Couillin, Isabelle, Mercier, Isabelle, Brombacher, Frank, Quesniaux, Valérie, Fossiez, Francois, Ryffel, Bernhard, Schnyder, Bruno

“…T helper (Th)17 cells producing interleukin (IL)-17 play a role in autoimmune and allergic inflammation. Here, we show that IL-23 induces IL-17 in the lung and…”
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Impaired Wound Healing of Alveolar Lung Epithelial Cells in a Breathing Lung-On-A-Chip by Felder, Marcel, Trueeb, Bettina, Stucki, Andreas Oliver, Borcard, Sarah, Stucki, Janick Daniel, Schnyder, Bruno, Geiser, Thomas, Guenat, Olivier Thierry

“…The lung alveolar region experiences remodeling during several acute and chronic lung diseases, as for instance idiopathic pulmonary fibrosis (IPF), a fatal…”
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Cigarette Smoke-Induced Pulmonary Inflammation Is TLR4/MyD88 and IL-1R1/MyD88 Signaling Dependent by Doz, Emilie, Noulin, Nicolas, Boichot, Elisabeth, Guenon, Isabelle, Fick, Lizette, Le Bert, Marc, Lagente, Vincent, Ryffel, Bernhard, Schnyder, Bruno, Quesniaux, Valerie F. J, Couillin, Isabelle

“…Acute cigarette smoke exposure of the airways (two cigarettes twice daily for three days) induces acute inflammation in mice. In this study, we show that…”
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Intact Staphylococcus Enterotoxin SEB from Culture Supernatant Detected by MALDI-TOF Mass Spectrometry by Tonacini, Jenna, Stephan, Dario, Vogel, Guido, Avondet, Marc-André, Kalman, Franka, Crovadore, Julien, Lefort, François, Schnyder, Bruno

“…Routine identification of pathogens by MALDI-TOF MS (matrix-assisted laser desorption ionisation time-of-flight mass spectrometry) is based on the fingerprint…”
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Toll-like receptor pathways in the immune responses to mycobacteria by Quesniaux, Valerie, Fremond, Cecile, Jacobs, Muazzam, Parida, Shreemanta, Nicolle, Delphine, Yeremeev, Vladimir, Bihl, Franck, Erard, Francois, Botha, Tania, Drennan, Michael, Soler, Marie-Noelle, Le Bert, Marc, Schnyder, Bruno, Ryffel, Bernhard

“…The control of Mycobacterium tuberculosis infection depends on recognition of the pathogen and the activation of both the innate and adaptive immune responses…”
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Murine Cerebral Malaria Development Is Independent of Toll-Like Receptor Signaling by Togbe, Dieudonnée, Schofield, Louis, Grau, Georges E, Schnyder, Bruno, Boissay, Victorine, Charron, Sabine, Rose, Stéphanie, Beutler, Bruce, Quesniaux, Valérie F.J, Ryffel, Bernhard

“…Malaria pigment hemozoin was reported to activate the innate immunity by Toll-like receptor (TLR)-9 engagement. However, the role of TLR activation for the…”
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Both Hemopoietic and Resident Cells Are Required for MyD88-Dependent Pulmonary Inflammatory Response to Inhaled Endotoxin by Noulin, Nicolas, Quesniaux, Valerie F. J, Schnyder-Candrian, Silvia, Schnyder, Bruno, Maillet, Isabelle, Robert, Thomas, Vargaftig, B. Boris, Ryffel, Bernhard, Couillin, Isabelle

“…Inhaled endotoxin induces an inflammatory response that contributes to the development and severity of asthma and other forms of airway disease. Here, we show…”
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Dual Effects of p38 MAPK on TNF-Dependent Bronchoconstriction and TNF-Independent Neutrophil Recruitment in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome by Schnyder-Candrian, Silvia, Quesniaux, Valerie F. J, Di Padova, Franco, Maillet, Isabelle, Noulin, Nicolas, Couillin, Isabelle, Moser, Rene, Erard, Francois, Vargaftig, B. Boris, Ryffel, Bernhard, Schnyder, Bruno

“…The administration of endotoxins from Gram-negative bacteria induces manifestations reminding of acute respiratory distress syndrome. p38 MAPKs have been…”
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TLR4 gene dosage contributes to endotoxin-induced acute respiratory inflammation by Togbe, Dieudonnée, Schnyder‐Candrian, Silvia, Schnyder, Bruno, Couillin, Isabelle, Maillet, Isabelle, Bihl, Franck, Malo, Danielle, Ryffel, Bernhard, Quesniaux, Valerie F. J.

“…Toll‐like receptor (TLR)4 is critical for endotoxin recognition and cellular responses. Using Tlr4 transgenic mice, we investigated the influence of Tlr4 gene…”
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Phytochemical Inhibition of Interleukin-4-Activated Stat6 and Expression of VCAM-1 by Schnyder, Bruno, Schnyder-Candrian, Silvia, Panski, Andreas, Bömmel, Heike, Heim, Markus, Duschl, Albert, Moser, René

“…Cellular functions induced by cytokine interleukin (IL)-4 and IL-4 signaling through signal transducer and activator of transcription (Stat)6 typify a Th2-type…”
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Inhibition of kinases impairs neutrophil activation and killing of Staphylococcus aureus by Schnyder, B, Meunier, P C, Car, B D

“…Intracellular phosphorylations polymorphonuclear neutrophils are mediated by kinases, including mitogen activated-protein (MAP) kinases and…”
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Interleukin-22 is a negative regulator of the allergic response by Schnyder, Bruno, Lima, Carla, Schnyder-Candrian, Silvia

“…A proinflammatory role of T helper (Th)17 cells, producing IL-22 and IL-17A, has been favored although there is evidence for negative immune regulation by…”
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Intact Staphylococcus Enterotoxin SEB from Culture Supernatant Detected by MALDI-TOF Mass Spectrometry by Tonacini, Jenna, Stephan, Dario, Vogel, Guido, Avondet, Marc-André, Kalman, Franka, Crovadore, Julien, Lefort, François, Schnyder, Bruno

“…Routine identification of pathogens by MALDI-TOF MS (matrix-assisted laser desorption ionisation time-of-flight mass spectrometry) is based on the fingerprint…”
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Distribution pattern of tenascin‐C in normal and neoplastic mesenchymal tissues by Schnyder, Bruno, Semadeni, Reto O., Fischer, René W., Vaughan, Lloyd, Car, Bruce D., Heitz, Philipp U., Winterhalter, Kaspar H., Odermatt, Bernhard F.

“…Descriptions for tenascin‐C distribution are largely restricted to epithelial tumours. The present study utilized newly developed and characterized monoclonal…”
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Toll-like receptor and tumour necrosis factor dependent endotoxin-induced acute lung injury by Togbe, Dieudonnée, Schnyder-Candrian, Silvia, Schnyder, Bruno, Doz, Emilie, Noulin, Nicolas, Janot, Laure, Secher, Thomas, Gasse, Pamela, Lima, Carla, Coelho, Fernando Rodrigues, Vasseur, Virginie, Erard, François, Ryffel, Bernhard, Couillin, Isabelle, Moser, Rene

“…Summary Recent studies on endotoxin/lipopolysaccharide (LPS)‐induced acute inflammatory response in the lung are reviewed. The acute airway inflammatory…”
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Whole-Genome Sequences of 15 Strains of Staphylococcus aureus subsp. aureus Isolated from Foodstuff and Human Clinical Samples by Crovadore, Julien, Calmin, Gautier, Tonacini, Jenna, Chablais, Romain, Baumgartner, Andreas, Schnyder, Bruno, Hodille, Elisabeth, Lefort, François

“…The whole-genome sequences of 15 strains of Staphylococcus aureus (10 strains isolated from foodstuff samples in Switzerland and five from human clinical…”
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Whole-Genome Sequences of Seven Strains of Bacillus cereus Isolated from Foodstuff or Poisoning Incidents by Crovadore, Julien, Calmin, Gautier, Tonacini, Jenna, Chablais, Romain, Schnyder, Bruno, Messelhäußer, Ute, Lefort, François

“…We present here the whole shotgun genome sequences of seven strains of Bacillus cereus isolated from foodstuff samples or food poisoning incidents…”
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Innate immunity to mycobacterial infection in mice: Critical role for toll-like receptors by Ryffel, Bernhard, Fremond, Cecile, Jacobs, Muazzam, Parida, Shreemanta, Botha, Tania, Schnyder, Bruno, Quesniaux, Valerie

“…Toll-like receptors (TLRs) play a critical role in the recognition of several pathogens, including Mycobacterium tuberculosis. Mycobacterial antigens recognize…”
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Endogenous leukemia inhibitory factor attenuates endotoxin response by Weber, Marietta A, Schnyder-Candrian, Silvia, Schnyder, Bruno, Quesniaux, Valerie, Poli, Valeria, Stewart, Colin L, Ryffel, Bernhard

“…Leukemia inhibitory factor (LIF) is induced in inflammation and likely plays a regulatory role. Using LIF-deficient mice (LIF−/−), we report here that…”
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