Search Results - "Schnizler, K"

Extracellular Acidosis Increases Neuronal Cell Calcium by Activating Acid-Sensing Ion Channel 1a by Yermolaieva, Olena, Leonard, A. Soren, Schnizler, Mikael K., Abboud, Francois M., Welsh, Michael J.

“…Acid-sensing ion channel (ASIC) 1a subunit is expressed in synapses of central neurons where it contributes to synaptic plasticity. However, whether these…”
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Targeting ASIC1a Reduces Innate Fear and Alters Neuronal Activity in the Fear Circuit by Coryell, Matthew W, Ziemann, Adam E, Westmoreland, Patricia J, Haenfler, Jill M, Kurjakovic, Zlatan, Zha, Xiang-ming, Price, Margaret, Schnizler, Mikael K, Wemmie, John A

“…Background The molecular mechanisms underlying innate fear are poorly understood. Previous studies indicated that the acid sensing ion channel ASIC1a…”
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Functional tetrodotoxin-resistant Na+ channels are expressed presynaptically in rat dorsal root ganglia neurons by Medvedeva, Y.V, Kim, M.-S, Schnizler, K, Usachev, Y.M

“…Abstract The tetrodotoxin-resistant (TTX-R) voltage-gated Na+ channels Nav 1.8 and Nav 1.9 are expressed by a subset of primary sensory neurons and have been…”
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Seizure termination by acidosis depends on ASIC1a by Schnizler, Mikael K, Wemmie, John A, Howard III, Matthew A, Welsh, Michael J, Ziemann, Adam E, Albert, Gregory W, Severson, Meryl A

“…Acidosis can stop seizures, but it is unclear how it does this. This study demonstrates that the acid-sensing channel ASIC1a is required for either spontaneous…”
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The Cytoskeletal Protein α-Actinin Regulates Acid-sensing Ion Channel 1a through a C-terminal Interaction by Schnizler, Mikael K., Schnizler, Katrin, Zha, Xiang-ming, Hall, Duane D., Wemmie, John A., Hell, Johannes W., Welsh, Michael J.

“…The acid-sensing ion channel 1a (ASIC1a) is widely expressed in central and peripheral neurons where it generates transient cation currents when extracellular…”
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Short-term exposure to waterborne free silver has acute effects on membrane current of Xenopus oocytes by Schnizler, Mikael K., Bogdan, Roman, Bennert, Anke, Bury, Nicolas R., Fronius, Martin, Clauss, Wolfgang

“…Waterborne free silver can cause osmo- and ionoregulatory disturbances in freshwater organisms. The effects of a short-term exposure to extracellular Ag + ions…”
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Evaluation of exposure of regorafenib (REG) and its metabolites in pediatric patients by modeling, simulation, and clinical study by Ploeger, B., Grevel, J., Frede, M., Block, M., Schnizler, K., Gerisch, M., Hafner, F.-T., Trnkova, Z.J., Agostinho, A.C., Sturm, I., Cleton, A.

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Evaluation of exposure of regorafenib and its metabolites in cancer patients with renal impairment by modelling, simulation, and clinical study by Block, M., Ploeger, B., Grevel, J., Schnizler, K., Gerisch, M., Hafner, F.-T., Reschke, S., Huang, F., Trnkova, Z.J., Sturm, I., Cleton, A.

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The Cytoskeletal Protein α-Actinin Regulates Acid-sensing Ion Channel 1a through a C-terminal Interaction by Mikael K. Schnizler, Katrin Schnizler, Xiang-ming Zha, Duane D. Hall, John A. Wemmie, Johannes W. Hell, Michael J. Welsh

“…The acid-sensing ion channel 1a (ASIC1a) is widely expressed in central and peripheral neurons where it generates transient cation currents when extracellular…”
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A Novel Chloride Channel in Drosophila melanogaster Is Inhibited by Protons by Schnizler, Katrin, Saeger, Beate, Pfeffer, Carsten, Gerbaulet, Alexander, Ebbinghaus-Kintscher, Ulrich, Methfessel, Christoph, Franken, Eva-Maria, Raming, Klaus, Wetzel, Christian H., Saras, Arunesh, Pusch, Hermann, Hatt, Hanns, Gisselmann, Günter

“…A systematic analysis of the Drosophila genome data reveals the existence of pHCl, a novel member of ligand-gated ion channel subunits. pHCl shows nearly…”
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The roboocyte: automated cDNA/mRNA injection and subsequent TEVC recording on Xenopus oocytes in 96-well microtiter plates by Schnizler, Katrin, Küster, Mike, Methfessel, Christoph, Fejtl, Michael

“…Membrane-bound neurotransmitter receptors and ion channels are among the most numerous and important drug targets, and electrophysiological methods are the…”
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Original Article: Targeting ASIC1a Reduces Innate Fear and Alters Neuronal Activity in the Fear Circuit by Coryell, Matthew W, Ziemann, Adam E, Westmoreland, Patricia J, Haenfler, Jill M, Kurjakovic, Zlatan, Zha, Xiang-ming, Price, Margaret, Schnizler, Mikael K, Wemmie, John A

“…The molecular mechanisms underlying innate fear are poorly understood. Previous studies indicated that the acid sensing ion channel ASIC1a influences fear…”
Get full text