Search Results - "Schnider, Jonas"

The Influence of Timing and Frequency of Adipose-Derived Mesenchymal Stem Cell Therapy on Immunomodulation Outcomes After Vascularized Composite Allotransplantation by Plock, Jan A, Schnider, Jonas T, Schweizer, Riccardo, Zhang, Wensheng, Tsuji, Wakako, Waldner, Matthias, Solari, Mario G, Marra, Kacey G, Rubin, J Peter, Gorantla, Vijay S

“…BACKGROUNDCellular therapies for immunomodulation in vascularized composite allotransplantation (VCA) have gained importance due to their potential for…”
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Adipose- and Bone Marrow-Derived Mesenchymal Stem Cells Prolong Graft Survival in Vascularized Composite Allotransplantation by Plock, Jan A, Schnider, Jonas T, Zhang, Wensheng, Schweizer, Riccardo, Tsuji, Wakako, Kostereva, Nataliya, Fanzio, Paolo M, Ravuri, Sudheer, Solari, Mario G, Cheng, Hui-Yun, Rubin, Peter J, Marra, Kacey G, Gorantla, Vijay S

“…Strategies aiming at minimization or elimination of systemic immunosuppression are key immediate goals for clinical expansion of vascularized composite…”
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Treg-inducing microparticles promote donor-specific tolerance in experimental vascularized composite allotransplantation by Fisher, James D., Balmert, Stephen C., Zhang, Wensheng, Schweizer, Riccardo, Schnider, Jonas T., Komatsu, Chiaki, Dong, Liwei, Erbas, Vasil E., Unadkat, Jignesh V., Aral, Ali Mübin, Acharya, Abhinav P., Kulahci, Yalcin, Turnquist, Heth R., Thomson, Angus W., Solari, Mario G., Gorantla, Vijay S., Little, Steven R.

“…For individuals who sustain devastating composite tissue loss, vascularized composite allotransplantation (VCA; e.g., hand and face transplantation) has the…”
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IGF-1 and Chondroitinase ABC Augment Nerve Regeneration after Vascularized Composite Limb Allotransplantation by Kostereva, Nataliya V, Wang, Yong, Fletcher, Derek R, Unadkat, Jignesh V, Schnider, Jonas T, Komatsu, Chiaki, Yang, Yang, Stolz, Donna B, Davis, Michael R, Plock, Jan A, Gorantla, Vijay S

“…Impaired nerve regeneration and inadequate recovery of motor and sensory function following peripheral nerve repair remain the most significant hurdles to…”
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Delivery of Rapamycin Using In Situ Forming Implants Promotes Immunoregulation and Vascularized Composite Allograft Survival by Sutter, Damian, Dzhonova, Dzhuliya V., Prost, Jean-Christophe, Bovet, Cedric, Banz, Yara, Rahnfeld, Lisa, Leroux, Jean-Christophe, Rieben, Robert, Vögelin, Esther, Plock, Jan A., Luciani, Paola, Taddeo, Adriano, Schnider, Jonas T.

“…Vascularized composite allotransplantation (VCA), such as hand and face transplantation, is emerging as a potential solution in patients that suffered severe…”
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Single Implantable FK506 Disk Prevents Rejection in Vascularized Composite Allotransplantation by Unadkat, Jignesh V., Schnider, Jonas T., Feturi, Firuz G., Tsuji, Wakako, Bliley, Jacqueline M., Venkataramanan, Raman, Solari, Mario G., Marra, Kacey G., Gorantla, Vijay S., Spiess, Alexander M.

“…In vascularized composite allotransplantation, medication nonadherence leads to increased acute rejections. Improving medication adherence would improve…”
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Pharmacokinetics and Biodistribution of Tacrolimus after Topical Administration: Implications for Vascularized Composite Allotransplantation by Feturi, Firuz G., Schnider, Jonas T., Fanzio, Paolo M., Erbas, Vasil E., Oksuz, Sinan, Sahin, Huseyin, Dong, Liwei, Unadkat, Jignesh M., Spiess, Alexander M., Plock, Jan A., Solari, Mario G., Gorantla, Vijay S., Venkataramanan, Raman

“…Aim The high doses of oral tacrolimus (TAC) ( 1 , 2 ) necessary to prevent acute rejection (AR) after vascularized composite allotransplantation (VCA) are…”
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Effects of immunosuppressive drugs on viability and susceptibility of adipose- and bone marrow-derived mesenchymal stem cells by Tsuji, Wakako, Schnider, Jonas T, McLaughlin, Meghan M, Schweizer, Riccardo, Zhang, Wensheng, Solari, Mario G, Rubin, J Peter, Marra, Kacey G, Plock, Jan A, Gorantla, Vijay S

“…The immunomodulatory potential of cell therapies using adipose-derived stem cells (ASCs) and bone marrow-derived mesenchymal stem cells (BM-MSCs) has been…”
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Review of the Early Diagnoses and Assessment of Rejection in Vascularized Composite Allotransplantation by Zheng, Xin Xiao, Schneeberger, Stefan, Schnider, Jonas T., Zhang, Wensheng, Carbonell, Jaime, Lee, W. P. Andrew, Brandacher, Gerald, Starzl, Ravi, Gorantla, Vijay S.

“…The emerging field of vascular composite allotransplantation (VCA) has become a clinical reality. Building upon cutting edge understandings of transplant…”
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Effect of Systemic Adipose-derived Stem Cell Therapy on Functional Nerve Regeneration in a Rodent Model by Schweizer, Riccardo, Schnider, Jonas T., Fanzio, Paolo M., Tsuji, Wakako, Kostereva, Nataliya, Solari, Mario G., Plock, Jan A., Gorantla, Vijay S.

“…BACKGROUND:Regardless of etiology, peripheral nerve injuries (PNI) result in disruption/loss of neuromuscular junctions, target muscle denervation, and poor…”
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Bone marrow-derived mesenchymal stromal cells improve vascular regeneration and reduce leukocyte-endothelium activation in critical ischemic murine skin in a dose-dependent manner by Schweizer, Riccardo, Kamat, Pranitha, Schweizer, Dennis, Dennler, Cyrill, Zhang, Shengye, Schnider, Jonas T, Salemi, Souzan, Giovanoli, Pietro, Eberli, Daniel, Enzmann, Volker, Erni, Dominique, Plock, Jan A

“…Abstract Background aims Stem cells participate in vascular regeneration following critical ischemia. However, their angiogenic and remodeling properties, as…”
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Perspectives on the use of mesenchymal stem cells in vascularized composite allotransplantation by Plock, Jan A, Schnider, Jonas T, Solari, Mario G, Zheng, Xin Xiao, Gorantla, Vijay S

“…Reconstructive transplantation has emerged as clinical reality over the past decade. Long-term graft acceptance has been feasible in extremity and facial…”
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Site-Specific Immunosuppression in Vascularized Composite Allotransplantation: Prospects and Potential by Gorantla, Vijay S., Venkataramanan, Raman, Solari, Mario G., Plock, Jan A., Weinstock, Matthias, Schnider, Jonas T., Zheng, Xin Xiao

“…Skin is the most immunogenic component of a vascularized composite allograft (VCA) and is the primary trigger and target of rejection. The skin is directly…”
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Are cultured mesenchymal stromal cells an option for immunomodulation in transplantation? by Plock, Jan A, Schnider, Jonas T, Schweizer, Riccardo, Gorantla, Vijay S

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Mycophenolic Acid for Topical Immunosuppression in Vascularized Composite Allotransplantation: Optimizing Formulation and Preliminary Evaluation of Bioavailability and Pharmacokinetics by Feturi, Firuz G, Weinstock, Matthias, Zhao, Wenchen, Zhang, Wei, Schnider, Jonas T, Erbas, Vasil E, Oksuz, Sinan, Plock, Jan A, Rohan, Lisa, Spiess, Alexander M, Ferreira, Lydia M, Solari, Mario G, Venkataramanan, Raman, Gorantla, Vijay S

“…Mycophenolic acid (MPA), is the active form of the ester prodrug mycophenolate mofetil (MMF). MMF is an FDA approved immunosuppressive drug that has been…”
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Hemoglobin vesicles improve wound healing and tissue survival in critically ischemic skin in mice by Plock, Jan A, Rafatmehr, Nassim, Sinovcic, Dubravko, Schnider, Jonas, Sakai, Hiromi, Tsuchida, Eishun, Banic, Andrej, Erni, Dominique

“…Local hypoxia, as due to trauma, surgery, or arterial occlusive disease, may severely jeopardize the survival of the affected tissue and its wound-healing…”
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Effect of C1-INH on ischemia/reperfusion injury in a porcine limb ex vivo perfusion model by Abdelhafez, Mai M., Shaw, Jane, Sutter, Damian, Schnider, Jonas, Banz, Yara, Jenni, Hansjörg, Voegelin, Esther, Constantinescu, Mihai A., Rieben, Robert

“…•Skeletal muscle I/R injury activates endothelial cells and plasma cascades.•Activated endothelial cells express FGL-2, leading to thrombin and fibrin…”
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Abstract P9: Non-Invasive Objective Evaluation of Peripheral Neuroregeneration Using Magnetic Resonance Diffusion Tensor Imaging by Kostereva, Nataliya, Lee, Vincent, Tobita, Kimimasa, Unadkat, Jignesh, Schnider, Jonas, Komatsu, Chiaki, Solari, Mario, Gorantla, Vijay

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Transgenic Expression of Human CD46 on Porcine Endothelium: Effect on Coagulation and Fibrinolytic Cascades During Ex Vivo Human-to-Pig Limb Xenoperfusions by Bongoni, Anjan K, Kiermeir, David, Schnider, Jonas, Jenni, Hansjörg, Garimella, Pavan, Bähr, Andrea, Klymiuk, Nikolai, Wolf, Eckhard, Ayares, David, Voegelin, Esther, Constantinescu, Mihai A, Seebach, Jörg D, Rieben, Robert

“…BACKGROUNDDysregulation of the coagulation system due to inflammatory responses and cross-species molecular incompatibilities represents a major obstacle to…”
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The protective role of C1-INH on ischemia reperfusion injury in a porcine limb amputation and reperfusion model by Abdelhafez, Mai M, Shaw, Jane, Sutter, Damian, Schnider, Jonas, Jenni, Hansjörg, Voegelin, Esther, Constantinescu, Mihai A, Rieben, Robert

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