Search Results - "Schneiderman, Jacob"

Intraarterial anti-leptin therapy via ICA protects ipsilateral CA1 neurons subjected to ischemia and reperfusion by Benbenishty, Amit, Schneiderman, Jacob

“…Brain reperfusion following an ischemic event is essential for tissue viability, however, it also involves processes that promote neuronal cell death. We have…”
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Cardiac leptin overexpression in the context of acute MI and reperfusion potentiates myocardial remodeling and left ventricular dysfunction by Kain, David, Simon, Amos J, Greenberg, Avraham, Ben Zvi, Danny, Gilburd, Boris, Schneiderman, Jacob

“…Acute MI induces leptin expression in the heart, however the role of myocardial leptin in cardiac ischemia and reperfusion (IR) remains unknown. To shed light…”
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Localized Antileptin Therapy Prevents Aortic Root Dilatation and Preserves Left Ventricular Systolic Function in a Murine Model of Marfan Syndrome by Fisch, Sudeshna, Bachner-Hinenzon, Noa, Ertracht, Offir, Guo, Liang, Arad, Yhara, Ben-Zvi, Danny, Liao, Ronglih, Schneiderman, Jacob

“…Background Marfan syndrome (MFS) is a genetically transmitted connective tissue disorder characterized by aortic root dilatation, dissection, and rupture…”
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Murine ultrasound imaging for circumferential strain analyses in the angiotensin II abdominal aortic aneurysm model by Favreau, John T., BS, Nguyen, Binh T., MD, Gao, Ian, BS, Yu, Peng, MD, Tao, Ming, MD, Schneiderman, Jacob, MD, Gaudette, Glenn R., PhD, Ozaki, C. Keith, MD

“…Objective The underlying causes of abdominal aortic aneurysms (AAAs) remain obscure, although research tools such as the angiotensin II (Ang II) apolipoprotein…”
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Local Application of Leptin Antagonist Attenuates Angiotensin II–Induced Ascending Aortic Aneurysm and Cardiac Remodeling by Ben‐Zvi, Danny, Savion, Naphtali, Kolodgie, Frank, Simon, Amos, Fisch, Sudeshna, Schäfer, Katrin, Bachner‐Hinenzon, Noa, Cao, Xin, Gertler, Arieh, Solomon, Gili, Kachel, Erez, Raanani, Ehud, Lavee, Jacob, Kotev Emeth, Shlomo, Virmani, Renu, Schoen, Frederick J., Schneiderman, Jacob

“…Background Ascending thoracic aortic aneurysm (ATAA) is driven by angiotensin II (AngII) and contributes to the development of left ventricular (LV) remodeling…”
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Long-term renin-angiotensin blocking therapy in hypertensive patients with normal aorta may attenuate the formation of abdominal aortic aneurysms by Silverberg, Daniel, Younis, Anan, Savion, Naphtali, Harari, Gil, Yakubovitch, Dmitry, Sheick Yousif, Basheer, Halak, Moshe, Grossman, Ehud, Schneiderman, Jacob

“…Renin-angiotensin system (RAS) has been implicated in the pathogenesis of abdominal aortic aneurysm (AAA). Angiotensin II type 1 receptor blocker (ARB), when…”
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Diagnosis of Thin-Cap Fibroatheromas by a Self-Contained Intravascular Magnetic Resonance Imaging Probe in Ex Vivo Human Aortas and In Situ Coronary Arteries by Schneiderman, Jacob, Wilensky, Robert L., Weiss, Assaf, Samouha, Eitzek, Muchnik, Lev, Chen-Zion, Malca, Ilovitch, Mordechay, Golan, Erez, Blank, Aharon, Flugelman, Moshe, Rozenman, Yosef, Virmani, Renu

“…We sought to correlate findings obtained from a self-contained magnetic resonance imaging (MRI) probe with plaque morphology of ex vivo human aortas and…”
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Leptin receptor is elevated in carotid plaques from neurologically symptomatic patients and positively correlated with augmented macrophage density by Schneiderman, Jacob, MD, Simon, Amos J., PhD, Schroeter, Marco R., MD, Flugelman, Moshe Y., MD, Konstantinides, Stavros, MD, Schaefer, Katrin, MD

“…Background Carotid artery lesions from symptomatic patients are characterized by inflammation and neovascularization. The adipokine leptin promotes…”
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Aging enhances abdominal aortic aneurysm formation and promotes aortic arch rupture in angiotensin II treated mice by Nguyen, Binh T., MD, Mizrahi, Boaz, PhD, Tao, Ming, MD, Yu, Peng, MD, Hao, Shawn, HS, Ozaki, C. Keith, MD, FACS, Schneiderman, Jacob, MD

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Endovascular Management of Mycotic Aortic Aneurysms by Silverberg, Daniel, Halak, Moshe, Yakubovitch, Dmitry, Reinitz, Emanuel-Ronny, Garniek, Alex, Rimon, Uri, Schneiderman, Jacob

“…Purpose: We report a single-center experience with the endovascular management of mycotic aortic aneurysms. Case reports: Four cases of mycotic aortic…”
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Intraarterial anti-leptin therapy via ICA protects ipsilateral CA1 neurons subjected to ischemia and reperfusion by Amit Benbenishty, Jacob Schneiderman

“…BackgroundBrain reperfusion following an ischemic event is essential for tissue viability, however, it also involves processes that promote neuronal cell…”
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Intrarenal Anti-Leptin Treatment Attenuates Ischemia and Reperfusion Injury by Jonas, Michael, Simon, Amos J, Gilburd, Boris, Schneiderman, Jacob

“…Renal ischemia and reperfusion (IR) injury introduces cellular stress and is the main cause of acute kidney damage. Renal cells exposed to noxious stress…”
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Regulation of PAI-1 gene expression in vivo by Loskutoff, D J, Sawdey, M, Keeton, M, Schneiderman, J

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Abciximab in Carotid Stenting for Postsurgical Carotid Restenosis: Intermediate Results by Schneiderman, Jacob, Morag, Benyamina, Gerniak, Alexander, Rimon, Uri, Varon, David, Seligsohn, Uri, Shotan, Avraham, Adar, Raphael

“…Purpose: To report intermediate results of a pilot study in which the glycoprotein IIb/IIIa receptor antagonist abciximab was given to patients during…”
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Locally Applied Leptin Induces Regional Aortic Wall Degeneration Preceding Aneurysm Formation in Apolipoprotein E–Deficient Mice by Tao, Ming, Yu, Peng, Nguyen, Binh T, Mizrahi, Boaz, Savion, Naphtali, Kolodgie, Frank D, Virmani, Renu, Hao, Shuai, Ozaki, C Keith, Schneiderman, Jacob

“…OBJECTIVE—Leptin promotes atherosclerosis and vessel wall remodeling. As abdominal aortic aneurysm (AAA) formation involves tissue remodeling, we hypothesized…”
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Phase Ib Safety, Two-Dose Study of MultiGeneAngio in Patients with Chronic Critical Limb Ischemia by Flugelman, Moshe Y., Halak, Moshe, Yoffe, Boris, Schneiderman, Jacob, Rubinstein, Chen, Bloom, Allan-Isaac, Weinmann, Eran, Goldin, Ilya, Ginzburg, Victor, Mayzler, Olga, Hoffman, Aaron, Koren, Belly, Gershtein, Diana, Inbar, Michal, Hutoran, Marina, Tsaba, Adili

“…Critical limb ischemia (CLI) is the most severe presentation of peripheral arterial disease. We developed cell-based therapy entailing intra-arterial injection…”
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Abstract 352: Locally Deployed Perivalvular Leptin Promotes Thickening of Aortic Valve Leaflets Associated with Remodeling of the Left Ventricle in ApoE-Deficient Mice by Ben Zvi, Danny, Fisch, Sudeshna, Ozaki, Keith C, Schoen, Fredrick J, Schneiderman, Jacob

“…Abstract only Background: Locally available leptin is involved in atherogenesis and remodeling of the arterial wall. Recently, we demonstrated its contribution…”
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Disrupted mobile aortic plaques are a major risk factor for systemic embolism in the elderly by Tenenbaum, A, Fisman, E Z, Schneiderman, J, Stroh, C I, Shemesh, J, Schwammenthal, E, Vered, Z, Motro, M

“…Protruding aortic plaques--especially those with mobile properties--on transesophageal echocardiography (TEE) are a potential source of stroke and systemic…”
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Tissue factor localization in non-human primate cerebral tissue by del Zoppo, G J, Yu, J Q, Copeland, B R, Thomas, W S, Schneiderman, J, Morrissey, J H

“…Tissue factor (TF), the principal procoagulant of human brain, resides in specific regions of the non-human primate central nervous system. Immunohistochemical…”
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Modulation of the fibrinolytic system by major peripheral ischemia by Schneiderman, Jacob, Eguchi, Yutaka, Adar, Raphael, Sawdey, Michael

“…Purpose: A rat model was developed to investigate the effects of acute peripheral ischemia on the components of the fibrinolytic system. Methods: Laparotomy…”
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