Search Results - "Schneider, Robert"

Arithmetic of partitions and the q-bracket operator by Schneider, Robert

“…We present a natural multiplicative theory of integer partitions (which are usually considered in terms of addition), and find many theorems of classical…”
Get full text

Lateral Thinking: How Histone Modifications Regulate Gene Expression by Lawrence, Moyra, Daujat, Sylvain, Schneider, Robert

“…The DNA of each cell is wrapped around histone octamers, forming so-called ‘nucleosomal core particles’. These histone proteins have tails that project from…”
Get full text

Histone post-translational modifications — cause and consequence of genome function by Millán-Zambrano, Gonzalo, Burton, Adam, Bannister, Andrew J., Schneider, Robert

“…Much has been learned since the early 1960s about histone post-translational modifications (PTMs) and how they affect DNA-templated processes at the molecular…”
Get full text

Translational Control in Cancer by Robichaud, Nathaniel, Sonenberg, Nahum, Ruggero, Davide, Schneider, Robert J

“…The translation of messenger RNAs (mRNAs) into proteins is a key event in the regulation of gene expression. This is especially true in the cancer setting, as…”
Get full text

The H1 linker histones: multifunctional proteins beyond the nucleosomal core particle by Hergeth, Sonja P, Schneider, Robert

“…The linker histone H1 family members are a key component of chromatin and bind to the nucleosomal core particle around the DNA entry and exit sites. H1 can…”
Get full text

The role of linker histone H1 modifications in the regulation of gene expression and chromatin dynamics by Izzo, Annalisa, Schneider, Robert

“…Linker histone H1 is a structural component of chromatin. It exists as a family of related proteins known as variants and/or subtypes. H1.1, H1.2, H1.3, H1.4…”
Get full text

DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity by Vanpouille-Box, Claire, Alard, Amandine, Aryankalayil, Molykutty J., Sarfraz, Yasmeen, Diamond, Julie M., Schneider, Robert J., Inghirami, Giorgio, Coleman, C. Norman, Formenti, Silvia C., Demaria, Sandra

“…Radiotherapy is under investigation for its ability to enhance responses to immunotherapy. However, the mechanisms by which radiation induces anti-tumour T…”
Get full text

Histone acylations and chromatin dynamics: concepts, challenges, and links to metabolism by Nitsch, Sandra, Zorro Shahidian, Lara, Schneider, Robert

“…In eukaryotic cells, DNA is tightly packed with the help of histone proteins into chromatin. Chromatin architecture can be modified by various…”
Get full text

Multifunctional role of the tumor associated monocytes/macrophages in the metastatic potential of inflammatory breast cancer by Mohamed, Mona Mostafa, Schneider, Robert J

“…Inflammatory breast cancer (IBC) is the most aggressive and lethal phenotype form of breast cancer, which afflicts young women at high incidence in North…”
Get full text

Dynamics and interplay of nuclear architecture, genome organization, and gene expression by Schneider, Robert, Grosschedl, Rudolf

“…The organization of the genome in the nucleus of a eukaryotic cell is fairly complex and dynamic. Various features of the nuclear architecture, including…”
Get full text

Inflammatory Breast Cancer Promotes Development of M2 Tumor-Associated Macrophages and Cancer Mesenchymal Cells through a Complex Chemokine Network by Valeta-Magara, Amanda, Gadi, Abhilash, Volta, Viviana, Walters, Beth, Arju, Rezina, Giashuddin, Shah, Zhong, Hua, Schneider, Robert J

“…Inflammatory breast cancer (IBC) is a highly aggressive form of breast cancer that displays profound cancer stem cell (CSC) and mesenchymal features that…”
Get full text

General route to design polymer molecular weight distributions through flow chemistry by Walsh, Dylan J., Schinski, Devin A., Schneider, Robert A., Guironnet, Damien

“…The properties of a polymer are known to be intrinsically related to its molecular weight distribution (MWD); however, previous methodologies of MWD control do…”
Get full text

CAD-CAM denture teeth made on cast metal removable partial denture frameworks by Muralidharan, Chandni, Schneider, Robert L., Kotowske, Sandra

“…Once the fit of the cast metal framework on a removable partial denture (RPD) has been verified, the manufacturer’s prefabricated denture teeth are typically…”
Get full text

A widespread alternate form of cap-dependent mRNA translation initiation by de la Parra, Columba, Ernlund, Amanda, Alard, Amandine, Ruggles, Kelly, Ueberheide, Beatrix, Schneider, Robert J.

“…Translation initiation of most mammalian mRNAs is mediated by a 5′ cap structure that binds eukaryotic initiation factor 4E (eIF4E). However, inactivation of…”
Get full text

Translational control in cancer by Schneider, Robert J, Silvera, Deborah, Formenti, Silvia C

“…Key Points Alterations in the expression and activity of specific translation factors, and the uncoupling of translational regulation from inhibition by tumour…”
Get full text

mRNA Decay Factor AUF1 Maintains Normal Aging, Telomere Maintenance, and Suppression of Senescence by Activation of Telomerase Transcription by Pont, Adam R., Sadri, Navid, Hsiao, Susan J., Smith, Susan, Schneider, Robert J.

“…Inflammation is associated with DNA damage, cellular senescence, and aging. Cessation of the inflammatory cytokine response is mediated in part through…”
Get full text

Elucidating binding mechanisms and dynamics of intrinsically disordered protein complexes using NMR spectroscopy by Schneider, Robert, Blackledge, Martin, Jensen, Malene Ringkjøbing

“…[Display omitted] •Intrinsically disordered proteins (IDPs) employ a variety of binding mechanisms.•They may form stable folded complex structures or remain…”
Get full text

Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer by Banh, Robert S., Biancur, Douglas E., Yamamoto, Keisuke, Sohn, Albert S.W., Walters, Beth, Kuljanin, Miljan, Gikandi, Ajami, Wang, Huamin, Mancias, Joseph D., Schneider, Robert J., Pacold, Michael E., Kimmelman, Alec C.

“…Pancreatic ductal adenocarcinoma (PDAC) tumors have a nutrient-poor, desmoplastic, and highly innervated tumor microenvironment. Although neurons can release…”
Get full text

Theory of routine mode choice decisions: An operational framework to increase sustainable transportation by Schneider, Robert J.

“…A growing number of communities in the United States are seeking to improve the sustainability of their transportation systems by shifting routine automobile…”
Get full text

Scratching the (lateral) surface of chromatin regulation by histone modifications by Tropberger, Philipp, Schneider, Robert

“…Whereas post-translational modifications (PTMs) in histone tails are well characterized, functional and mechanistic insights into PTMs in the globular…”
Get full text