Search Results - "Schnabl, Bernd"

Microbiota and Fatty Liver Disease-the Known, the Unknown, and the Future by Lang, Sonja, Schnabl, Bernd

“…The liver communicates with the intestine via the portal vein, biliary system, and mediators in the circulation. Microbes in the intestine maintain liver…”
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Role of innate immunity and the microbiota in liver fibrosis: crosstalk between the liver and gut by Seki, Ekihiro, Schnabl, Bernd

“…Liver fibrosis occurs as a wound‐healing scar response following chronic liver inflammation including alcoholic liver disease, non‐alcoholic steatohepatitis,…”
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Interactions Between the Intestinal Microbiome and Liver Diseases by Schnabl, Bernd, Brenner, David A

“…The human intestine harbors a diverse community of microbes that promote metabolism and digestion in their symbiotic relationship with the host. Disturbance of…”
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Bacteriophages and their potential for treatment of gastrointestinal diseases by Duan, Yi, Young, Ry, Schnabl, Bernd

“…Although bacteriophages have been overshadowed as therapeutic agents by antibiotics for decades, the emergence of multidrug-resistant bacteria and a better…”
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Intestinal microbiota and nonalcoholic steatohepatitis by Brandl, Katharina, Schnabl, Bernd

“…PURPOSE OF REVIEWNonalcoholic fatty liver disease (NAFLD) is a liver disease with high prevalence in western countries. Progression from NAFLD to nonalcoholic…”
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Gut microbiome, liver immunology, and liver diseases by Wang, Rui, Tang, Ruqi, Li, Bo, Ma, Xiong, Schnabl, Bernd, Tilg, Herbert

“…The gut microbiota is a complex and plastic consortium of microorganisms that are intricately connected with human physiology. The liver is a central…”
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Mechanisms of decompensation and organ failure in cirrhosis: From peripheral arterial vasodilation to systemic inflammation hypothesis by Bernardi, Mauro, Moreau, Richard, Angeli, Paolo, Schnabl, Bernd, Arroyo, Vicente

“…Summary The peripheral arterial vasodilation hypothesis has been most influential in the field of cirrhosis and its complications. It has given rise to…”
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Gut mycobiome alterations and implications for liver diseases by Zeng, Suling, Schnabl, Bernd

“…Chronic liver disease and its complications are a significant global health burden. Changes in fungal communities (mycobiome), an integral component of the gut…”
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Alcoholic Liver Disease: The Gut Microbiome and Liver Cross Talk by Hartmann, Phillipp, Seebauer, Caroline T., Schnabl, Bernd

“…Alcoholic liver disease (ALD) is a leading cause of morbidity and mortality worldwide. Alcoholic fatty liver disease can progress to steatohepatitis, alcoholic…”
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Antimicrobial proteins: intestinal guards to protect against liver disease by Hendrikx, Tim, Schnabl, Bernd

“…Alterations of gut microbes play a role in the pathogenesis and progression of many disorders including liver and gastrointestinal diseases. Both qualitative…”
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Immunoglobulin A and liver diseases by Inamine, Tatsuo, Schnabl, Bernd

“…Immunoglobulin A (IgA) is a major immunoglobulin isotype in the gut and plays a role in maintenance of gut homeostasis. Secretory IgA (SIgA) has multiple…”
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The microbiota in cirrhosis and its role in hepatic decompensation by Trebicka, Jonel, Macnaughtan, Jane, Schnabl, Bernd, Shawcross, Debbie L., Bajaj, Jasmohan S.

“…Cirrhosis – the common end-stage of chronic liver disease – is associated with a cascade of events, of which intestinal bacterial overgrowth and dysbiosis are…”
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Liver cirrhosis and immune dysfunction by Hasa, Elda, Hartmann, Phillipp, Schnabl, Bernd

“…Abstract Cirrhosis is end-stage liver disease resulting from various etiologies and is a common cause of death worldwide. The progression from compensated to…”
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New mitochondrial DNA synthesis enables NLRP3 inflammasome activation by Zhong, Zhenyu, Liang, Shuang, Sanchez-Lopez, Elsa, He, Feng, Shalapour, Shabnam, Lin, Xue-jia, Wong, Jerry, Ding, Siyuan, Seki, Ekihiro, Schnabl, Bernd, Hevener, Andrea L., Greenberg, Harry B., Kisseleva, Tatiana, Karin, Michael

“…Dysregulated NLRP3 inflammasome activity results in uncontrolled inflammation, which underlies many chronic diseases. Although mitochondrial damage is needed…”
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Precision medicine in alcoholic and nonalcoholic fatty liver disease via modulating the gut microbiota by Bluemel, Sena, Williams, Brandon, Knight, Rob, Schnabl, Bernd

“…Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) represent a major health burden in industrialized countries. Although alcohol abuse…”
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Dysbiosis‐induced intestinal inflammation activates tumor necrosis factor receptor I and mediates alcoholic liver disease in mice by Chen, Peng, Stärkel, Peter, Turner, Jerrold R., Ho, Samuel B., Schnabl, Bernd

“…Intestinal barrier dysfunction is an important contributor to alcoholic liver disease (ALD). Translocated microbial products trigger an inflammatory response…”
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Role of the intestinal microbiome in liver fibrosis development and new treatment strategies by Zhou, Rongrong, Fan, Xuegong, Schnabl, Bernd

“…Liver cirrhosis is a major cause of morbidity and mortality worldwide. The most common chronic liver diseases in western countries are alcohol-associated liver…”
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Bacteria engineered to produce IL-22 in intestine induce expression of REG3G to reduce ethanol-induced liver disease in mice by Hendrikx, Tim, Duan, Yi, Wang, Yanhan, Oh, Jee-Hwan, Alexander, Laura M, Huang, Wendy, Stärkel, Peter, Ho, Samuel B, Gao, Bei, Fiehn, Oliver, Emond, Patrick, Sokol, Harry, van Pijkeren, Jan-Peter, Schnabl, Bernd

“…Antimicrobial C-type lectin regenerating islet-derived 3 gamma (REG3G) is suppressed in the small intestine during chronic ethanol feeding. Our aim was to…”
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Microbiome 101: Studying, Analyzing, and Interpreting Gut Microbiome Data for Clinicians by Allaband, Celeste, McDonald, Daniel, Vázquez-Baeza, Yoshiki, Minich, Jeremiah J., Tripathi, Anupriya, Brenner, David A., Loomba, Rohit, Smarr, Larry, Sandborn, William J., Schnabl, Bernd, Dorrestein, Pieter, Zarrinpar, Amir, Knight, Rob

“…Advances in technical capabilities for reading complex human microbiomes are leading to an explosion of microbiome research, leading in turn to intense…”
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From intestinal dysbiosis to alcohol-associated liver disease by Mendes, Beatriz Garcia, Schnabl, Bernd

“…Alcohol-associated intestinal dysbiosis and bacterial overgrowth can lead to a dysregulation of tryptophan metabolism and lower production of indoles. Several…”
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