Search Results - "Schnütgen, F"

Single-Stranded DNA-Binding Transcriptional Regulator FUBP1 Is Essential for Fetal and Adult Hematopoietic Stem Cell Self-Renewal by Rabenhorst, Uta, Thalheimer, Frederic B., Gerlach, Katharina, Kijonka, Marek, Böhm, Stefanie, Krause, Daniela S., Vauti, Franz, Arnold, Hans-Henning, Schroeder, Timm, Schnütgen, Frank, von Melchner, Harald, Rieger, Michael A., Zörnig, Martin

“…The ability of hematopoietic stem cells (HSCs) to self-renew is a prerequisite for the establishment of definitive hematopoiesis and life-long blood…”
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A directional strategy for monitoring Cre-mediated recombination at the cellular level in the mouse by Ghyselinck, Norbert B, Schnütgen, Frank, Doerflinger, Nathalie, Wendling, Olivia, Calléja, Cécile, Chambon, Pierre

“…Functional redundancies, compensatory mechanisms, and lethal phenotypes often prevent the full analysis of gene functions through generation of germline null…”
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The expression pattern of a novel gene encoding brain-fatty acid binding protein correlates with neuronal and glial cell development by Kurtz, A, Zimmer, A, Schnütgen, F, Brüning, G, Spener, F, Müller, T

“…Fatty acid binding proteins (FABPs) are a multigene family of small intracellular proteins that bind hydrophobic ligands. In this report we describe the…”
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Genome wide conditional mouse knockout resources by Kaloff, C., Anastassiadis, K., Ayadi, A., Baldock, R., Beig, J., Birling, M.-C., Bradley, A., Brown, S.D.M., Bürger, A., Bushell, W., Chiani, F., Collins, F.S., Doe, B., Eppig, J.T., Finnell, R.H., Fletcher, C., Flicek, P., Fray, M., Friedel, R.H., Gambadoro, A., Gates, H., Hansen, J., Herault, Y., Hicks, G.G., Hörlein, A., Hrabé de Angelis, M., Iyer, V., de Jong, P.J., Koscielny, G., Kühn, R., Liu, P., Lloyd, K.C.K, Lopez, R.G., Marschall, S., Martínez, S., McKerlie, C., Meehan, T., von Melchner, H., Moore, M., Murray, S.A., Nagy, A., Nutter, L.M.J., Pavlovic, G., Pombero, A., Prosser, H., Ramirez-Solis, R., Ringwald, M., Rosen, B., Rosenthal, N., Rossant, J., Ruiz Noppinger, P., Ryder, E., Skarnes, W.C., Schick, J., Schnütgen, F., Schofield, P., Seisenberger, C., Selloum, M., Smedley, D., Simpson, E.M., Stewart, A.F., Teboul, L., Tocchini Valentini, G.P., Valenzuela, D., West, A.P., Wurst, W.

“…The International Knockout Mouse Consortium (IKMC) developed high throughput gene trapping and gene targeting pipelines that produced mostly conditional…”
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Isolation and characterization of two fatty acid binding proteins from mouse brain by Myers-Payne, S C, Hubbell, T, Pu, L, Schnütgen, F, Börchers, T, Wood, W G, Spener, F, Schroeder, F

“…Two fatty acid binding proteins (FABPs) were isolated from Swiss Webster mouse brains. Neither protein cross-reacted with antisera to recombinant liver L-FABP…”
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Stable Oxidative Cytosine Modifications Accumulate in Cardiac Mesenchymal Cells From Type2 Diabetes Patients: Rescue by α-Ketoglutarate and TET-TDG Functional Reactivation by Spallotta, Francesco, Cencioni, Chiara, Atlante, Sandra, Garella, Davide, Cocco, Mattia, Mori, Mattia, Mastrocola, Raffaella, Kuenne, Carsten, Guenther, Stefan, Nanni, Simona, Azzimato, Valerio, Zukunft, Sven, Kornberger, Angela, Sürün, Duran, Schnütgen, Frank, von Melchner, Harald, Di Stilo, Antonella, Aragno, Manuela, Braspenning, Maarten, van Criekinge, Wim, De Blasio, Miles J, Ritchie, Rebecca H, Zaccagnini, Germana, Martelli, Fabio, Farsetti, Antonella, Fleming, Ingrid, Braun, Thomas, Beiras-Fernandez, Andres, Botta, Bruno, Collino, Massimo, Bertinaria, Massimo, Zeiher, Andreas M, Gaetano, Carlo

“…RATIONALE:Human cardiac mesenchymal cells (CMSCs) are a therapeutically relevant primary cell population. Diabetes mellitus compromises CMSC function as…”
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Heterologous expression and characterisation of mouse brain fatty acid binding protein by Schnütgen, F, Börchers, T, Müller, T, Spener, F

“…A novel brain-type member of the fatty acid binding protein family (B-FABP) was heterologously expressed in Escherichia coli, either as inclusion bodies at 37…”
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Generation of multipurpose alleles for the functional analysis of the mouse genome by Schnutgen, F.

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Genomewide Production of Multipurpose Alleles for the Functional Analysis of the Mouse Genome by Schnütgen, Frank, De-Zolt, Silke, Van Sloun, Petra, Hollatz, Melanie, Floss, Thomas, Hansen, Jens, Altschmied, Joachim, Seisenberger, Claudia, Ghyselinck, Norbert B., Ruiz, Patricia, Chambon, Pierre, Wurst, Wolfgang, von Melchner, Harald

“…A type of retroviral gene trap vectors has been developed that can induce conditional mutations in most genes expressed in mouse embryonic stem (ES) cells. The…”
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A Large-Scale, Gene-Driven Mutagenesis Approach for the Functional Analysis of the Mouse Genome by Hansen, Jens, Floss, Thomas, Van Sloun, Petra, Füchtbauer, Ernst-Martin, Vauti, Franz, Arnold, Hans-Hennig, Schnütgen, Frank, Wurst, Wolfgang, von Melchner, Harald, Ruiz, Patricia

“…A major challenge of the postgenomic era is the functional characterization of every single gene within the mammalian genome. In an effort to address this…”
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Crystal structure and thermodynamic analysis of human brain fatty acid-binding protein by Balendiran, G K, Schnutgen, F, Scapin, G, Borchers, T, Xhong, N, Lim, K, Godbout, R, Spener, F, Sacchettini, J C

“…Expression of brain fatty acid-binding protein (B-FABP) is spatially and temporally correlated with neuronal differentiation during brain development…”
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The expression pattern of a novel gene encoding brain-fatty acid binding protein correlated with neuronal and glial cell development by KURTZ, A, ZIMMER, A, SCHNÜTGEN, F, BRÜNING, G, SPENER, F, MÜLLER, T

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High-throughput trapping of secretory pathway genes in mouse embryonic stem cells by De-Zolt, Silke, Schnütgen, Frank, Seisenberger, Claudia, Hansen, Jens, Hollatz, Melanie, Floss, Thomas, Ruiz, Patricia, Wurst, Wolfgang, von Melchner, Harald

“…High-throughput gene trapping is a random approach for inducing insertional mutations across the mouse genome. This approach uses gene trap vectors that…”
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Generation of multipurpose alleles for the functional analysis of the mouse genome by Schnutgen, F.

“…A novel generation of retroviral gene-trap vectors has been developed with the ability to induce conditional mutations in most genes expressed in mouse…”
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