Search Results - "Schnölzer, M."
-
1
Molecular architecture of the DED chains at the DISC: regulation of procaspase-8 activation by short DED proteins c-FLIP and procaspase-8 prodomain
Published in Cell death and differentiation (01-04-2016)“…The CD95/Fas/APO-1 death-inducing signaling complex (DISC), comprising CD95, FADD, procaspase-8, procaspase-10, and c-FLIP, has a key role in apoptosis…”
Get full text
Journal Article -
2
Combining Click Chemistry-Based Proteomics With Dox-Inducible Gene Expression
Published in Methods in enzymology (2017)“…Inactivating mutations in single genes can trigger, prevent, promote, or alleviate diseases. Identifying such disease-related genes is a main pillar of medical…”
Get more information
Journal Article -
3
Proteome analysis of lipofuscin in human retinal pigment epithelial cells
Published in FEBS letters (25-09-2002)“…Excessive accumulation of lipofuscin in postmitotic retinal pigment epithelial cells is a common pathogenetic pathway in various blinding retinal diseases…”
Get full text
Journal Article -
4
A new silver staining apparatus and procedure for matrix-assisted laser desorption/ionization-time of flight analysis of proteins after two-dimensional electrophoresis
Published in Proteomics (Weinheim) (01-07-2001)“…We report on a new silver stain especially developed for staining large gels (25 cm× 20 cm) from the Hoefer ISO‐DALT system for matrix‐assisted laser…”
Get full text
Journal Article -
5
Acetylation of the HIV-1 Tat protein by p300 is important for its transcriptional activity
Published in Current biology (16-12-1999)“…The human immunodeficiency virus 1 (HIV-1) Tat protein activates transcriptional elongation by recruiting the positive transcription elongation factor (pTEFb)…”
Get full text
Journal Article -
6
PAMAM Structure-Based Multifunctional Fluorescent Conjugates for Improved Fluorescent Labelling of Biomacromolecules
Published in Chemistry : a European journal (19-09-2008)“…Fluorescent probes are of increasing interest in medicinal and biological applications for the elucidation of the structures and functions of healthy as well…”
Get full text
Journal Article -
7
Calcium-signaling networks in olfactory receptor neurons
Published in Neuroscience (06-02-2008)“…Abstract The olfactory neuroepithelium represents a unique interface between the brain and the external environment. Olfactory function comprises a distinct…”
Get full text
Journal Article -
8
Interaction of plakophilins with desmoplakin and intermediate filament proteins: an in vitro analysis
Published in Journal of cell science (01-07-2000)“…Plakophilin 1 and 2 (PKP1, PKP2) are members of the arm-repeat protein family. They are both constitutively expressed in most vertebrate cells, in two splice…”
Get full text
Journal Article -
9
Adipocyte differentiation-related protein is secreted into milk as a constituent of milk lipid globule membrane
Published in Biochemical journal (15-12-1996)“…Milk lipid globules from humans, cows and rats contained a protein identified as adipocyte differentiation-related protein (ADRP) associated with the globule…”
Get full text
Journal Article -
10
First Isolation of Human UDP-d-Xylose: Proteoglycan Core Protein β-d-Xylosyltransferase Secreted from Cultured JAR Choriocarcinoma Cells
Published in The Journal of biological chemistry (16-02-2001)“…Human UDP-d-xylose:proteoglycan core protein β-d-xylosyltransferase (EC 2.4.2.26, XT) initiates the biosynthesis of glycosaminoglycan lateral chains in…”
Get full text
Journal Article -
11
Nuclear Particles Containing RNA Polymerase III Complexes Associated with the Junctional Plaque Protein Plakophilin 2
Published in Proceedings of the National Academy of Sciences - PNAS (03-07-2001)“…Plakophilin 2, a member of the arm-repeat protein family, is a dual location protein that occurs both in the cytoplasmic plaques of desmosomes as an…”
Get full text
Journal Article -
12
-
13
Towards a two-dimensional proteome map of Mycoplasma pneumoniae
Published in Electrophoresis (01-11-2000)“…A Proteome map of the bacterium Mycoplasma pneumoniae was constructed using two‐dimensional (2‐D) gel electrophoresis in combination with mass spectrometry…”
Get full text
Journal Article -
14
Identification of novel proteins associated with the development of chemoresistance in malignant melanoma using two-dimensional electrophoresis
Published in Electrophoresis (01-08-2000)“…A model system for studying chemoresistance in human melanoma cells (MeWo) has been established utilizing the four commonly used cytotoxic drugs vindesine,…”
Get full text
Journal Article -
15
-
16
Constructing Proteins by Dovetailing Unprotected Synthetic Peptides: Backbone-Engineered HIV Protease
Published in Science (American Association for the Advancement of Science) (10-04-1992)“…Backbone-engineered HIV-1 protease was prepared by a total chemical synthesis approach that combines the act of joining two peptides with the generation of an…”
Get full text
Journal Article -
17
Characterization of the differential protein expression associated with thermoresistance in human gastric carcinoma cell lines
Published in Electrophoresis (01-08-2001)“…Resistance to chemotherapeutic agents is one of the major problems faced during palliative therapy of tumor cells. Thus, chemotherapy is frequently combined…”
Get full text
Journal Article -
18
Proteome analysis of isolated myenteric plexus reveals significant changes in protein expression during postnatal development
Published in Autonomic neuroscience (30-10-2005)“…The enteric nervous system in vertebrates is the most complex part of the peripheral nervous system. Concerning chemical coding, ultrastructure and neuronal…”
Get full text
Journal Article -
19
Differential protein expression in the epidermis of wild-type and COX-2 transgenic mice
Published in Skin pharmacology and physiology (01-01-2006)“…Cyclooxygenases (COX) 1 and 2 are the key enzymes of prostaglandin biosynthesis. Like in many tissues, in adult skin COX-1 is a constitutive 'housekeeping'…”
Get more information
Journal Article -
20
Proteomic analysis reveals successive aberrations in protein expression from healthy mucosa to invasive head and neck cancer
Published in Oncogene (04-01-2007)“…Development of head and neck squamous cell carcinoma (HNSCC) is a multistep process and in many cases involves a phenomenon coined 'field cancerization'. In…”
Get full text
Journal Article