Search Results - "Schmitz, Jonathan F"
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Mechanisms of transcription factor evolution in Metazoa
Published in Nucleic acids research (27-07-2016)“…Transcriptions factors (TFs) are pivotal for the regulation of virtually all cellular processes, including growth and development. Expansions of TF families…”
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Fact or fiction: updates on how protein-coding genes might emerge de novo from previously non-coding DNA
Published in F1000 research (2017)“…Over the last few years, there has been an increasing amount of evidence for the emergence of protein-coding genes, i.e. out of non-coding DNA. Here, we review…”
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Stochastic Gain and Loss of Novel Transcribed Open Reading Frames in the Human Lineage
Published in Genome biology and evolution (03-11-2020)“…Abstract In addition to known genes, much of the human genome is transcribed into RNA. Chance formation of novel open reading frames (ORFs) can lead to the…”
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Evolution of novel genes in three-spined stickleback populations
Published in Heredity (01-08-2020)“…Eukaryotic genomes frequently acquire new protein-coding genes which may significantly impact an organism's fitness. Novel genes can be created, for example,…”
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The Goddard and Saturn Genes Are Essential for Drosophila Male Fertility and May Have Arisen De Novo
Published in Molecular biology and evolution (01-05-2017)“…New genes arise through a variety of mechanisms, including the duplication of existing genes and the de novo birth of genes from noncoding DNA sequences. While…”
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Incipient de novo genes can evolve from frozen accidents that escaped rapid transcript turnover
Published in Nature ecology & evolution (01-10-2018)“…A recent surge of studies have suggested that many novel genes arise de novo from previously noncoding DNA and not by duplication. However, most studies…”
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